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Šárka Pospíšilová

Šárka Pospíšilová

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
12108
World Ranking
14370
National Ranking
18

Overview

Šárka Pospíšilová is affiliated with Masaryk University in the Czech Republic. Their research focuses on medicine, with significant contributions in biochemistry, genetics, and molecular biology. The scientist has an extensive record in genetics, pathology and forensic medicine, molecular biology, immunology, and oncology.

The primary topics covered in their research include chronic lymphocytic leukemia, lymphoma diagnosis and treatment, immunodeficiency and autoimmune disorders, cancer genomics and diagnostics, CAR-T cell therapy research, advanced breast cancer therapies, and chronic myeloid leukemia treatments.

Šárka Pospíšilová has published prominently in several scientific journals. The most frequent publication venues are Blood with 16 papers, Leukemia with 11 papers, HemaSphere with 10 papers, bioRxiv (Cold Spring Harbor Laboratory) with 5 papers, and Haematologica with 4 papers.

Recent publications by Šárka Pospíšilová include:

  • International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia, 2020, Blood
  • Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL, 2020, Blood
  • Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multi-center study, 2020, Haematologica
  • Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target, 2020, Haematologica
  • miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors, 2021, Blood

Frequent co-authors of Šárka Pospíšilová include:

  • Michael Doubek
  • Karla Plevová
  • Paolo Ghia
  • Richard Rosenquist
  • Šárka Pavlová

Best Publications

  • Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies

    Andreas Agathangelidis;Nikos Darzentas;Anastasia Hadzidimitriou;Xavier Brochet

  • Towards error-free profiling of immune repertoires

    Mikhail Shugay;Olga V Britanova;Ekaterina M Merzlyak;Maria A Turchaninova

  • Recurrent mutations refine prognosis in chronic lymphocytic leukemia.

    P Baliakas;A Hadzidimitriou;L-A Sutton;D Rossi

  • ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia.

    S Pospisilova;D Gonzalez;J Malcikova;M Trbusek

  • MicroRNA isolation and stability in stored RNA samples.

    Marek Mráz;Karla Malinová;Jiří Mayer;Šárka Pospíšilová

  • A Complex Role for FGF‐2 in Self‐Renewal, Survival, and Adhesion of Human Embryonic Stem Cells

    Livia Eiselleova;Kamil Matulka;Vitezslav Kriz;Michaela Kunova

  • miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities

    Marek Mraz;K Malinova;J Kotaskova;Sarka Pavlova

  • Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact

    Panagiotis Baliakas;Sabine Jeromin;Michalis Iskas;Anna Puiggros

  • Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival, and response to DNA damage.

    Jitka Malcikova;Jana Smardova;Ludmila Rocnova;Boris Tichy

  • A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study

    A. C. Rawstron;C. Fazi;A. Agathangelidis;N. Villamor

  • TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations

    T. Zenz;D. Vollmer;Martin Trbušek;Jana Šmardová

  • MicroRNA biogenesis, functionality and cancer relevance.

    Branislav Kusenda;Marek Mraz;Jiri Mayer;Sarka Pospisilova

  • ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation

    J. Malcikova;J. Malcikova;E. Tausch;D. Rossi;Lesley Ann Sutton;Lesley Ann Sutton

  • High-quality full-length immunoglobulin profiling with unique molecular barcoding.

    M. A. Turchaninova;M. A. Turchaninova;M. A. Turchaninova;Alexey Nikolayevich Davydov;O. V. Britanova;O. V. Britanova;Mikhail Shugay;Mikhail Shugay

  • MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia

    Karin Vargova;Nikola Curik;Pavel Burda;Petra Basova

  • Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia.

    J Malcikova;K Stano-Kozubik;B Tichy;B Kantorova

  • Reproducible diagnosis of Chronic Lymphocytic Leukemia by flow cytometry: an European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) harmonisation project

    Andy C Rawstron;Karl-Anton Kreuzer;Asha Soosapilla;Martin Spacek

  • Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations.

    Viktor Ljungström;Diego Cortese;Emma Young;Tatjana Pandzic

  • Chromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic data.

    Panagiotis Baliakas;Michalis Iskas;Anne Gardiner;Zadie Davis

  • MicroRNAs in chronic lymphocytic leukemia pathogenesis and disease subtypes.

    Marek Mraz;Sarka Pospisilova;Karla Malinova;Ivo Slapak

Frequent Co-Authors

Richard Rosenquist
Richard Rosenquist Karolinska Institute
Paolo Ghia
Paolo Ghia Vita-Salute San Raffaele University
Kostas Stamatopoulos
Kostas Stamatopoulos Centre for Research and Technology Hellas
David Oscier
David Oscier Royal Bournemouth Hospital
Frederic Davi
Frederic Davi Assistance Publique – Hôpitaux de Paris
Davide Rossi
Davide Rossi European Society for Medical Oncology
Gianluca Gaidano
Gianluca Gaidano University of Eastern Piedmont Amadeo Avogadro
Gunnar Juliusson
Gunnar Juliusson Lund University
Anton W. Langerak
Anton W. Langerak Erasmus University Rotterdam
Nicholas Chiorazzi
Nicholas Chiorazzi Feinstein Institute for Medical Research

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