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Biology and Biochemistry

D-Index
72
Citations
19200
World Ranking
6281
National Ranking
2949

Overview

John W. Christman is affiliated with The Ohio State University in the United States. Their research primarily focuses on fields related to Medicine, with a significant number of publications in subfields such as Pulmonary and Respiratory Medicine, Immunology, Molecular Biology, Physiology, and Epidemiology.

The scientist's work covers a variety of main topics, including:

  • Neonatal Respiratory Health Research
  • Respiratory Support and Mechanisms
  • Extracellular vesicles in disease
  • Immune cells in cancer
  • Asthma and respiratory diseases
  • Sepsis Diagnosis and Treatment
  • Immune Response and Inflammation

John W. Christman has contributed to numerous papers. Some recent publications include:

  • Nanoparticle delivery of microRNA-146a regulates mechanotransduction in lung macrophages and mitigates injury during mechanical ventilation (2021, Nature Communications)
  • A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury (2020, Nature Communications)
  • Macrophage HIF-1α mediates obesity-related adipose tissue dysfunction via interleukin-1 receptor-associated kinase M (2020, American Journal of Physiology-Endocrinology and Metabolism)
  • Workforce, Workload, and Burnout in Critical Care Organizations: Survey Results and Research Agenda (2020, Critical Care Medicine)
  • PolyADP-Ribosylation of NFATc3 and NF-κB Transcription Factors Modulate Macrophage Inflammatory Gene Expression in LPS-Induced Acute Lung Injury (2020, Journal of Innate Immunity)

The scientist collaborates frequently with other researchers. Notable frequent co-authors include:

  • Sangwoon Chung
  • Manjula Karpurapu
  • Joshua A. Englert
  • Megan N. Ballinger
  • Navjotsingh Pabla

John W. Christman's work has been published repeatedly in key scientific venues such as:

  • American Journal of Respiratory and Critical Care Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Innate Immunity
  • American Journal of Physiology-Lung Cellular and Molecular Physiology

Best Publications

  • Oxidative Stress and NF-κB Activation: Correlation in Patients Following Allogeneic Bone Marrow Transplantation

    Timothy S. Blackwell;John W. Christman;Terri Hagan;Patricia Price

  • The role of nuclear factor-kappa B in cytokine gene regulation.

    Timothy S. Blackwell;John W. Christman

  • Pathogen-host interactions in Pseudomonas aeruginosa pneumonia.

    Ruxana T. Sadikot;Timothy S. Blackwell;John W. Christman;Alice S. Prince

  • Sepsis and cytokines: current status.

    T S Blackwell;J W Christman

  • In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation.

    T S Blackwell;T R Blackwell;E P Holden;B W Christman

  • Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial.

    Michael A Matthay;Carolyn S Calfee;Hanjing Zhuo;B Taylor Thompson

  • The Role of Nuclear Factor-κ B in Pulmonary Diseases

    John W. Christman;Ruxana T. Sadikot;Timothy S. Blackwell

  • Nuclear factor kappa B: a pivotal role in the systemic inflammatory response syndrome and new target for therapy.

    J. W. Christman;L. H. Lancaster;T. S. Blackwell

  • Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway.

    Gökhan M. Mutlu;David Green;Amy Bellmeyer;Christina M. Baker

  • Duration and Intensity of NF-κB Activity Determine the Severity of Endotoxin-Induced Acute Lung Injury

    M. Brett Everhart;Wei Han;Taylor P. Sherrill;Melissa Arutiunov

  • The Role of Nuclear Factor Kappa B in the Pathogenesis of Pulmonary Diseases: Implications for Therapy

    Jeffrey G. Wright;Jeffrey G. Wright;John W. Christman;John W. Christman

  • Monocytes Are Potent Facilitators of Alveolar Neutrophil Emigration During Lung Inflammation: Role of the CCL2-CCR2 Axis

    Ulrich A. Maus;Katharina Waelsch;William A. Kuziel;Tim Delbeck

  • Resident Alveolar Macrophages Are Replaced by Recruited Monocytes in Response to Endotoxin-Induced Lung Inflammation

    Ulrich A. Maus;Simeon Janzen;Gerhard Wall;Mrigank Srivastava

  • Exaggerated Activation of Nuclear Factor- κ B and Altered I κ B- β Processing in Cystic Fibrosis Bronchial Epithelial Cells

    Annapurna Venkatakrishnan;Arlene A. Stecenko;Gayle King;Thomas R. Blackwell

  • Airway Epithelium Controls Lung Inflammation and Injury through the NF-κB Pathway

    Dong Sheng Cheng;Wei Han;Sabrina M. Chen;Taylor P. Sherrill

  • NADPH oxidase limits innate immune responses in the lungs in mice.

    Brahm H. Segal;Brahm H. Segal;Wei Han;Jennifer J. Bushey;Myungsoo Joo

  • Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases

    Gye Young Park;John W. Christman

  • Multiorgan nuclear factor kappa B activation in a transgenic mouse model of systemic inflammation.

    Timothy S. Blackwell;Fiona E. Yull;Chih-Li Chen;Annapurna Venkatakrishnan

  • Redox regulation of nuclear factor kappa B: therapeutic potential for attenuating inflammatory responses.

    John W. Christman;Timothy S. Blackwell;Bernhard H.J. Juurlink

  • Recruited alveolar macrophages, in response to airway epithelial-derived monocyte chemoattractant protein 1/CCl2, regulate airway inflammation and remodeling in allergic asthma.

    Yong Gyu Lee;Jong Jin Jeong;Sharmilee Nyenhuis;Evgeny Berdyshev

Frequent Co-Authors

Timothy S. Blackwell
Timothy S. Blackwell University of Michigan–Ann Arbor
Ruxana T. Sadikot
Ruxana T. Sadikot University of Nebraska Medical Center
Fiona E. Yull
Fiona E. Yull Vanderbilt University
Steven J. Ackerman
Steven J. Ackerman University of Illinois at Chicago
Tobias Welte
Tobias Welte University of Hannover
Asrar B. Malik
Asrar B. Malik University of Illinois at Chicago
Viswanathan Natarajan
Viswanathan Natarajan University of Illinois at Chicago
Richard D. Ye
Richard D. Ye Chinese University of Hong Kong, Shenzhen
Werner Seeger
Werner Seeger University of Giessen
James C. Paton
James C. Paton University of Adelaide

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