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Biology and Biochemistry

D-Index
48
Citations
8467
World Ranking
18382
National Ranking
7506

Overview

Ruxana T. Sadikot is affiliated with the University of Nebraska Medical Center in the United States. Their research spans several domains within medicine and molecular biology, with a focus on pulmonary and respiratory medicine. The extensive publication record reflects significant engagement in fields such as epidemiology, infectious diseases, and cancer research.

Their recent publications cover topics related to chronic airway inflammation, infectious disease severity, mycobacterial infections, and mitochondrial dysfunction in bacterial infections. Notable works include:

  • "Molecular and Cellular Mechanisms Responsible for Beneficial Effects of Mesenchymal Stem Cell-Derived Product "Exo-d-MAPPS" in Attenuation of Chronic Airway Inflammation" (2020, Analytical Cellular Pathology)
  • "sTREM-1 Predicts Disease Severity and Mortality in COVID-19 Patients: Involvement of Peripheral Blood Leukocytes and MMP-8 Activity" (2021, Viruses)
  • "Macrophage Signaling Pathways in Pulmonary Nontuberculous Mycobacteria Infections" (2020, American Journal of Respiratory Cell and Molecular Biology)
  • "Efficacy and safety of azithromycin versus placebo to treat lower respiratory tract infections associated with low procalcitonin: a randomised, placebo-controlled, double-blind, non-inferiority trial" (2022, The Lancet Infectious Diseases)
  • "Mitochondrial Dysfunction in Bacterial Infections" (2023, Pathogens)

Frequent co-authors collaborating with Sadikot include:

  • Zhihong Yuan
  • Brahmchetna Bedi
  • Pedro V. da Silva-Neto
  • Jonatan C. S. de Carvalho
  • Vinícius E. Pimentel

Their publications have appeared predominantly in journals such as:

  • Pathogens
  • CHEST Journal
  • American Journal of Respiratory and Critical Care Medicine
  • Pulmonary Circulation
  • The FASEB Journal

Main fields of study are medicine and biochemistry, genetics, and molecular biology, with focused subfields in:

  • Pulmonary and Respiratory Medicine
  • Epidemiology
  • Molecular Biology
  • Infectious Diseases
  • Cancer Research

Their main research topics include:

  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cystic Fibrosis Research Advances
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Pneumocystis jirovecii pneumonia detection and treatment

Best Publications

  • Pathogen-host interactions in Pseudomonas aeruginosa pneumonia.

    Ruxana T. Sadikot;Timothy S. Blackwell;John W. Christman;Alice S. Prince

  • Early identification of patients at risk of acute lung injury: Evaluation of lung injury prediction score in a multicenter cohort study

    Ognjen Gajic;Ousama Dabbagh;Pauline K. Park;Adebola Adesanya

  • The Role of Nuclear Factor-κ B in Pulmonary Diseases

    John W. Christman;Ruxana T. Sadikot;Timothy S. Blackwell

  • Cigarette smoking and innate immunity.

    H. Mehta;K. Nazzal;R. T. Sadikot

  • Duration and Intensity of NF-κB Activity Determine the Severity of Endotoxin-Induced Acute Lung Injury

    M. Brett Everhart;Wei Han;Taylor P. Sherrill;Melissa Arutiunov

  • Pseudomonas aeruginosa Biofilms: Host Response and Clinical Implications in Lung Infections.

    Nicholas M. Maurice;Nicholas M. Maurice;Brahmchetna Bedi;Ruxana T. Sadikot;Ruxana T. Sadikot

  • Mesenchymal Stem Cell-Based Therapy of Inflammatory Lung Diseases: Current Understanding and Future Perspectives.

    C. Randall Harrell;Ruxana Sadikot;Ruxana Sadikot;Jose Pascual;Crissy Fellabaum

  • Macrophages Are Necessary for Maximal Nuclear Factor- κ B Activation in Response to Endotoxin

    M. Audrey Koay;Xiang Gao;Mary Kay Washington;Kelly S. Parman

  • Targeted Immunomodulation of the NF-κB Pathway in Airway Epithelium Impacts Host Defense against Pseudomonas aeruginosa

    Ruxana T. Sadikot;Ruxana T. Sadikot;Heng Zeng;Myungsoo Joo;M. Brett Everhart

  • Functional genomics of silencing TREM-1 on TLR4 signaling in macrophages

    M. Ornatowska;A. C. Azim;X. Wang;J. W. Christman

  • Non-tuberculous mycobacterial disease is common in patients with non-cystic fibrosis bronchiectasis.

    Mehdi Mirsaeidi;Walid Hadid;Walid Hadid;Basel Ericsoussi;Basel Ericsoussi;Daniel Rodgers

  • Selective IκB Kinase Expression in Airway Epithelium Generates Neutrophilic Lung Inflammation

    Ruxana T. Sadikot;Wei Han;M. Brett Everhart;Ornella Zoia

  • Curcumin and lung cancer—a review

    Hiren J. Mehta;Vipul Patel;Ruxana T. Sadikot

  • PGD Synthase and PGD2 in Immune Resposne

    Myungsoo Joo;Ruxana T. Sadikot;Ruxana T. Sadikot

  • Hepatitis C Virus Core Protein Suppresses NF-κB Activation and Cyclooxygenase-2 Expression by Direct Interaction with IκB Kinase β

    Myungsoo Joo;Young S. Hahn;Minjae Kwon;Ruxana T. Sadikot

  • p47phox Deficiency Impairs NF-κB Activation and Host Defense in Pseudomonas Pneumonia

    Ruxana T. Sadikot;Heng Zeng;Fiona E. Yull;Bo Li

  • Achromobacter respiratory infections.

    Colin E. Swenson;Ruxana T. Sadikot

  • High-Dose Dexamethasone Accentuates Nuclear Factor- κ B Activation in Endotoxin-Treated Mice

    Ruxana T. Sadikot;E. Duco Jansen;Thomas R. Blackwell;Ornella Zoia

  • FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa

    Yuru Liu;Ruxana T. Sadikot;Ruxana T. Sadikot;Guy R. Adami;Vladimir V. Kalinichenko

  • Bacterial clearance of Pseudomonas aeruginosa is enhanced by the inhibition of COX-2

    Ruxana T. Sadikot;Ruxana T. Sadikot;Ruxana T. Sadikot;Heng Zeng;Anser C. Azim;Myungsoo Joo

Frequent Co-Authors

John W. Christman
John W. Christman The Ohio State University
Timothy S. Blackwell
Timothy S. Blackwell University of Michigan–Ann Arbor
Fiona E. Yull
Fiona E. Yull Vanderbilt University
Joanna B. Goldberg
Joanna B. Goldberg Emory University
Michael Koval
Michael Koval Emory University
Dolly Mehta
Dolly Mehta University of Illinois at Chicago
R. Stokes Peebles
R. Stokes Peebles Vanderbilt University
Clement Kleinstreuer
Clement Kleinstreuer North Carolina State University
Richard W. Light
Richard W. Light Vanderbilt University
Yu-Kyoung Oh
Yu-Kyoung Oh Seoul National University

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