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Biology and Biochemistry

D-Index
51
Citations
9659
World Ranking
17147
National Ranking
7064

Overview

Martha Kirby is affiliated with the National Institutes of Health in the United States. Their research encompasses a broad range of topics primarily within biochemistry, genetics, and molecular biology, with notable contributions to medicine. The scientist's work focuses on several subfields, including molecular biology, immunology, cell biology, hematology, and neurology.

Their research interests cover key areas such as immune cell function and interaction, single-cell and spatial transcriptomics, epigenetics and DNA methylation, zebrafish biomedical research applications, acute myeloid leukemia research, inflammasome and immune disorders, and the long-term effects of COVID-19.

Frequent publication venues for this researcher include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Nature Communications
  • Blood Advances
  • BMC Bioinformatics

Selected recent papers authored or co-authored by Martha Kirby are:

  • "Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children," 2022, Nature Immunology
  • "In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells," 2022, Nature Communications
  • "Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development," 2021, Blood Advances
  • "Snapshot: a package for clustering and visualizing epigenetic history during cell differentiation," 2023, BMC Bioinformatics
  • "Optimized methods for scRNA-seq and snRNA-seq of skeletal muscle stored in nucleic acid stabilizing preservative," 2025, Communications Biology

Martha Kirby has collaborated frequently with several co-authors across multiple projects, including Stacie M. Anderson, Stephen Wincovitch, Erica Bresciani, Raman Sood, and Paul Liu.

Best Publications

  • Roles for Insulin Receptor, PI3-Kinase, and Akt in Insulin-Signaling Pathways Related to Production of Nitric Oxide in Human Vascular Endothelial Cells

    Guangyuan Zeng;Frederick H. Nystrom;Lingamanaidu V. Ravichandran;Li-Na Cong

  • The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness.

    Tuoqi Wu;Yun Ji;E. Ashley Moseman;Haifeng C. Xu

  • Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons.

    Shibeshih Belachew;Ramesh Chittajallu;Ramesh Chittajallu;Adan A. Aguirre;Xiaoqing Yuan

  • Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection.

    Chen Yao;Hong-Wei Sun;Neal E. Lacey;Yun Ji

  • Regulation of CSF1 Promoter by the SWI/SNF-like BAF Complex

    Rui Liu;Hong Liu;Xin Chen;Martha Kirby

  • Paroxysmal Nocturnal Hemoglobinuria Cells in Patients with Bone Marrow Failure Syndromes

    Daniel E. Dunn;Patcharin Tanawattanacharoen;Piernicola Boccuni;Shoichi Nagakura

  • Differential Expression of Interleukin-17A and -17F Is Coupled to T Cell Receptor Signaling via Inducible T Cell Kinase

    Julio Gomez-Rodriguez;Nisebita Sahu;Robin Handon;Todd S. Davidson

  • Maintenance of alveolitis in patients with chronic beryllium disease by beryllium-specific helper T cells.

    Cesare Saltini;Karen Winestock;Martha Kirby;Paula Pinkston

  • Cell cycle delay and apoptosis are induced by high salt and urea in renal medullary cells.

    L. Michea;D. R. Ferguson;E. M. Peters;P. M. Andrews

  • Significant Human β-Cell Turnover Is Limited to the First Three Decades of Life as Determined by in Vivo Thymidine Analog Incorporation and Radiocarbon Dating

    Shira Y. Perl;J. A. Kushner;B. A. Buchholz;A. K. Meeker

  • Bias toward use of a specific T cell receptor beta-chain variable region in a subgroup of individuals with sarcoidosis.

    D R Moller;K Konishi;M Kirby;B Balbi

  • SAP regulates T cell–mediated help for humoral immunity by a mechanism distinct from cytokine regulation

    Jennifer L. Cannons;Li J. Yu;Dragana Jankovic;Shane Crotty

  • Biased accumulation of T lymphocytes with "memory"-type CD45 leukocyte common antigen gene expression on the epithelial surface of the human lung.

    C Saltini;M Kirby;B C Trapnell;N Tamura

  • Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells

    Julio Gomez-Rodriguez;Elizabeth A. Wohlfert;Robin Handon;Françoise Meylan

  • Peripheral blood CD34+ cells differ from bone marrow CD34+ cells in Thy-1 expression and cell cycle status in nonhuman primates mobilized or not mobilized with granulocyte colony-stimulating factor and/or stem cell factor.

    R E Donahue;M R Kirby;M R Kirby;M E Metzger;M E Metzger;B A Agricola;B A Agricola

  • Increased cytotoxic T cells with effector phenotype in aplastic anemia and myelodysplasia.

    Hoon Kook;Weihua Zeng;Chen Guibin;Martha Kirby

  • Requirements for selection of conventional and innate T lymphocyte lineages.

    Reiko Horai;Kristen L. Mueller;Robin A. Handon;Jennifer L. Cannons

  • Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation

    Michael J. Nemeth;Martha R. Kirby;David M. Bodine

  • Increased numbers of T lymphocytes with gamma delta-positive antigen receptors in a subgroup of individuals with pulmonary sarcoidosis.

    Bruno Balbi;David R. Moller;Martha Kirby;Kenneth J. Holroyd

  • Similarities in Function and Gene Structure of Cytohesin-4 and Cytohesin-1, Guanine Nucleotide-exchange Proteins for ADP-ribosylation Factors

    Masahito Ogasawara;Sei-Chang Kim;Ronald Adamik;Akira Togawa

Frequent Co-Authors

Stacie M. Anderson
Stacie M. Anderson National Institutes of Health
Pamela L. Schwartzberg
Pamela L. Schwartzberg National Institutes of Health
Ronald G. Crystal
Ronald G. Crystal Cornell University
Fabio Candotti
Fabio Candotti National Institutes of Health
Robert E. Donahue
Robert E. Donahue National Institutes of Health
J. Joseph Melenhorst
J. Joseph Melenhorst University of Pennsylvania
John F. Tisdale
John F. Tisdale National Institutes of Health
Neal S. Young
Neal S. Young National Institutes of Health
David M. Bodine
David M. Bodine National Institutes of Health
Koichi Kawakami
Koichi Kawakami National Institute of Genetics

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