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Immunology

D-Index
72
Citations
18315
World Ranking
2218
National Ranking
42

Overview

Johan Grunewald is affiliated with Karolinska University Hospital in Sweden and has a research focus primarily in Medicine, with a strong emphasis on Physiology and Pulmonary and Respiratory Medicine. Their work spans several subfields including Epidemiology, Molecular Biology, and Public Health, Environmental and Occupational Health.

The scientist's contributions include extensive research on sarcoidosis, beryllium toxicity, interstitial lung diseases, and idiopathic pulmonary fibrosis. Their main topics of investigation cover:

  • Sarcoidosis and Beryllium Toxicity Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Drug-Induced Adverse Reactions
  • Autoimmune and Inflammatory Disorders
  • Infectious Diseases and Tuberculosis
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • S100 Proteins and Annexins

Frequent publication venues include Respiratory Medicine, Frontiers in Medicine, and the European Respiratory Journal, among others:

  • Respiratory Medicine (4 publications)
  • Frontiers in Medicine (4 publications)
  • European Respiratory Journal (3 publications)
  • ERJ Open Research (2 publications)
  • Arthritis Research & Therapy (2 publications)

Their recent papers show a focus on sarcoidosis and related immune responses, reflecting various facets of disease management and pathophysiology. Notable papers include:

  • Challenges of Sarcoidosis and Its Management, 2021, New England Journal of Medicine
  • CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope, 2021, The Journal of Experimental Medicine
  • Monocytes in sarcoidosis are potent tumour necrosis factor producers and predict disease outcome, 2021, European Respiratory Journal
  • Risk of first and recurrent serious infection in sarcoidosis: a Swedish register-based cohort study, 2020, European Respiratory Journal
  • Infection risk in sarcoidosis patients treated with methotrexate compared to azathioprine: A retrospective 'target trial' emulated with Swedish real-world data, 2021, Respirology

Johan Grunewald has collaborated frequently with various researchers, with the most frequent coauthors being:

  • Susanna Kullberg
  • Anders Eklúnd
  • Elizabeth V. Arkema
  • Natalia V. Rivera
  • Marios Rossides

Best Publications

  • A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination.

    Lars Klareskog;Patrik Stolt;Karin Lundberg;Henrik Källberg

  • Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

    D Makrygiannakis;M Hermansson;A-K Ulfgren;A P Nicholas

  • Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid.

    C. Admyre;J. Grunewald;J. Thyberg;S. Gripenbäck

  • Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients

    Bettina Levänen;Nirav R. Bhakta;Patricia Torregrosa Paredes;Rebecca Barbeau

  • Increased Risk for Cancer Following Sarcoidosis

    Johan Askling;Johan Grunewald;Anders Eklund;Gunnar Hillerdal

  • Sarcoidosis incidence and prevalence: a nationwide register-based assessment in Sweden

    Elizabeth V. Arkema;Johan Grunewald;Susanna Kullberg;Anders Eklund

  • HLA-DR Predicts the Prognosis in Scandinavian Patients with Pulmonary Sarcoidosis

    Mary Berlin;Anna Fogdell-Hahn;Olle Olerup;Anders Eklund

  • Structural changes and antibody enrichment in the lungs are early features of anti-citrullinated protein antibody-positive rheumatoid arthritis.

    Gudrun Reynisdottir;Reza Karimi;Vijay Joshua;Helga Olsen

  • Löfgren's syndrome: human leukocyte antigen strongly influences the disease course.

    Johan Grunewald;Anders Eklund

  • Smoking, Use of Moist Snuff, and Risk of Chronic Inflammatory Diseases

    Cecilia Carlens;Maria-Pia Hergens;Johan Grunewald;Anders Ekbom

  • Bronchoalveolar lavage fluid exosomes contribute to cytokine and leukotriene production in allergic asthma

    P. Torregrosa Paredes;J. Esser;C. Admyre;M. Nord

  • Analysis of Intracellular Cytokines in CD4+ and CD8+ Lung and Blood T Cells in Sarcoidosis

    Jan Wahlström;Kianoosh Katchar;Hans Wigzell;Olle Olerup

  • The lung microbiota in early rheumatoid arthritis and autoimmunity

    Jose U. Scher;Vijay Joshua;Alejandro Artacho;Shahla Abdollahi-Roodsaz

  • Antibacterial components in bronchoalveolar lavage fluid from healthy individuals and sarcoidosis patients.

    Birgitta Agerberth;Johan Grunewald;Esmeralda Castaños-Velez;Berit Olsson

  • T Cell Responses to Mycobacterial Catalase-Peroxidase Profile a Pathogenic Antigen in Systemic Sarcoidosis

    Edward S. Chen;Jan Wahlström;Zhimin Song;Matthew H. Willett

  • Human Leukocyte Antigen Class I Alleles and the Disease Course in Sarcoidosis Patients

    Johan Grunewald;Anders Eklund;Olle Olerup

  • Restricted Vα2.3 gene usage by CD4+ T lymphocytes in bronchoalveolar lavage fluid from sarcoidosis patients correlates with HLA-DR3

    Johan Grunewald;Carl Harald Janson;Anders Eklund;Mary Öhrn

  • Sex-specific manifestations of Löfgren's syndrome.

    Johan Grunewald;Anders Eklund

  • Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis

    Khaleda R Qazi;Patricia Torregrosa Paredes;Benita Dahlberg;Johan Grunewald

  • T cell receptor V-segment frequencies in peripheral blood T cells correlate with human leukocyte antigen type.

    Beena Gulwani-Akolkar;David N. Posnett;Carl Harald Janson;Johan Grunewald

Frequent Co-Authors

Anders Eklund
Anders Eklund Karolinska Institute
Anca I. Catrina
Anca I. Catrina Karolinska University Hospital
Mahmood Jeddi-Tehrani
Mahmood Jeddi-Tehrani Avicenna Research Institute
Johan Askling
Johan Askling Karolinska Institute
Lars Klareskog
Lars Klareskog Karolinska Institute
Leonid Padyukov
Leonid Padyukov Karolinska Institute
Susanne Gabrielsson
Susanne Gabrielsson Karolinska Institute
Håkan Mellstedt
Håkan Mellstedt Karolinska Institute
Olle Olerup
Olle Olerup Karolinska Institute
Johan Rönnelid
Johan Rönnelid Uppsala University

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