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Leonid Padyukov

Leonid Padyukov

D-Index & Metrics

Immunology

D-Index
95
Citations
42481
World Ranking
880
National Ranking
15

Medicine

D-Index
95
Citations
44033
World Ranking
9907
National Ranking
193

Overview

Leonid Padyukov is a researcher affiliated with the Karolinska Institute in Sweden, focusing extensively on medicine with particular expertise in rheumatology, immunology, and genetics. Their work intersects multiple subfields including molecular biology and pathology and forensic medicine.

The main areas of study for Leonid include systemic lupus erythematosus research, rheumatoid arthritis research and therapies, and T-cell and B-cell immunology. Other significant research topics cover chronic lymphocytic leukemia research, genetic associations and epidemiology, inflammatory myopathies and dermatomyositis, and monoclonal and polyclonal antibodies research.

They have published extensively in venues such as:

  • Annals of the Rheumatic Diseases
  • Arthritis & Rheumatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Lara D. Veeken

Frequent collaborators include Lars Klareskog, Lars Alfredsson, Ingrid E. Lundberg, Saedís Saevarsdóttir, and Johan Askling, indicating a strong network within the rheumatology and immunology research communities.

Among their recent publications are:

  • "Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets," 2023, Nature Immunology
  • "Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis," 2022, Nature Genetics
  • "Genetics of rheumatoid arthritis," 2022, Seminars in Immunopathology
  • "FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease," 2020, Nature
  • "Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction," 2020, Nature Communications

Best Publications

  • Genetics of rheumatoid arthritis contributes to biology and drug discovery

    Yukinori Okada;Yukinori Okada;Di Wu;Di Wu;Di Wu;Gosia Trynka;Gosia Trynka;Towfique Raj;Towfique Raj

  • A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination.

    Lars Klareskog;Patrik Stolt;Karin Lundberg;Henrik Källberg

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

    Eli A Stahl;Soumya Raychaudhuri;Soumya Raychaudhuri;Elaine F Remmers;Gang Xie

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus

    Elaine F. Remmers;Robert M. Plenge;Annette T. Lee;Robert R. Graham;Robert R. Graham

  • Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

    Hunna J. Watson;Hunna J. Watson;Hunna J. Watson;Zeynep Yilmaz;Laura M. Thornton;Christopher Hübel;Christopher Hübel

  • Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

    Soumya Raychaudhuri;Cynthia Sandor;Eli A. Stahl;Eli A. Stahl;Jan Freudenberg

  • Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

    Yun Liu;Martin J Aryee;Leonid Padyukov;M Daniele Fallin;M Daniele Fallin

  • TRAF1–C5 as a Risk Locus for Rheumatoid Arthritis — A Genomewide Study

    Robert M. Plenge;Mark Seielstad;Leonid Padyukov;Annette T. Lee

  • A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

    Vesela Gateva;Johanna K. Sandling;Geoff Hom;Kimberly E. Taylor

  • A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis

    Leonid Padyukov;Camilla Silva;Patrik Stolt;Lars Alfredsson

  • High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

    Steve Eyre;John Bowes;John Bowes;Dorothée Diogo;Dorothée Diogo;Annette Lee

  • Genome-wide association identifies multiple ulcerative colitis susceptibility loci

    Dermot P.B. McGovern;Agnès Gardet;Leif Törkvist;Philippe Goyette

  • Two independent alleles at 6q23 associated with risk of rheumatoid arthritis

    Robert M Plenge;Robert M Plenge;Robert M Plenge;Chris Cotsapas;Chris Cotsapas;Leela Davies;Alkes L Price;Alkes L Price

  • Common variants at CD40 and other loci confer risk of rheumatoid arthritis

    Soumya Raychaudhuri;Soumya Raychaudhuri;Soumya Raychaudhuri;Elaine F Remmers;Annette T Lee;Rachel Hackett

  • Immunity to Citrullinated Proteins in Rheumatoid Arthritis

    Lars Klareskog;Johan Rönnelid;Karin Lundberg;Leonid Padyukov

  • Gene-Gene and Gene-Environment Interactions Involving HLA-DRB1, PTPN22, and Smoking in Two Subsets of Rheumatoid Arthritis

    Henrik Källberg;Leonid Padyukov;Robert M. Plenge;Robert M. Plenge;Johan Rönnelid

  • Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4.

    Robert M. Plenge;Leonid Padyukov;Elaine F. Remmers;Shaun Purcell

  • Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke.

    Henrik Källberg;Bo Ding;Leonid Padyukov;Camilla Bengtsson

  • Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

    Lee Ph;Anttila;Won H

Frequent Co-Authors

Lars Klareskog
Lars Klareskog Karolinska Institute
Lars Alfredsson
Lars Alfredsson Karolinska Institute
Robert M. Plenge
Robert M. Plenge Bristol Myers Squibb
Peter K. Gregersen
Peter K. Gregersen Feinstein Institute for Medical Research
Jane Worthington
Jane Worthington University of Manchester
Eli A. Stahl
Eli A. Stahl Icahn School of Medicine at Mount Sinai
Soumya Raychaudhuri
Soumya Raychaudhuri Brigham and Women's Hospital
Ingrid E. Lundberg
Ingrid E. Lundberg Karolinska University Hospital
Iva Gunnarsson
Iva Gunnarsson Karolinska University Hospital

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