World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
11878
World Ranking
17020
National Ranking
7015

Overview

Brendan D. Price is affiliated with Harvard University in the United States and works primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research encompasses subfields including Molecular Biology, Oncology, Physiology, Pathology and Forensic Medicine, and Cancer Research.

Their main research topics cover areas such as DNA Repair Mechanisms, CRISPR and Genetic Engineering, Advanced biosensing and bioanalysis techniques, PARP inhibition in cancer therapy, Calcium signaling and nucleotide metabolism, Genetic factors in colorectal cancer, and Colorectal Cancer Treatments and Studies.

Scientific collaborations have been established with frequent co-authors including Jacob V. Layer, Nealia C. House, Hongyun Qi, Ramya Parasuram, and Roni H. G. Wright.

Brendan D. Price has contributed publications to several notable journals, including Cell Reports, Molecular Oncology, Proceedings of the National Academy of Sciences, Oncogene, and PLoS ONE.

  • The ADP-ribose hydrolase NUDT5 is important for DNA repair, 2022, Cell Reports
  • The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer, 2021, Molecular Oncology
  • Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair, 2020, Proceedings of the National Academy of Sciences
  • HJURP is recruited to double-strand break sites and facilitates DNA repair by promoting chromatin reorganization, 2024, Oncogene
  • Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage, 2020, PLoS ONE

Best Publications

  • A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

    Yingli Sun;Xiaofeng Jiang;Shujuan Chen;Norvin Fernandes

  • Chromatin Remodeling at DNA Double-Strand Breaks

    Brendan D. Price;Alan D. D’Andrea

  • Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

    Yingli Sun;Xiaofeng Jiang;Ye Xu;Marina K. Ayrapetov

  • Sequential Phosphorylation by Mitogen-activated Protein Kinase and Glycogen Synthase Kinase 3 Represses Transcriptional Activation by Heat Shock Factor-1

    Boyang Chu;Fabrice Soncin;Brendan D. Price;Mary Ann Stevenson

  • Constitutive activation of IκB kinase α and NF-κB in prostate cancer cells is inhibited by ibuprofen

    S T Palayoor;M Y Youmell;S K Calderwood;C N Coleman

  • DNA Damage-Induced Acetylation of Lysine 3016 of ATM Activates ATM Kinase Activity

    Yingli Sun;Ye Xu;Kanaklata Roy;Brendan D. Price

  • Caffeine inhibits the checkpoint kinase ATM

    Alessandra Blasina;Brendan D. Price;Gaetan A. Turenne;Clare H. McGowan

  • DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin.

    Marina K. Ayrapetov;Ozge Gursoy-Yuzugullu;Chang Xu;Ye Xu

  • Histone H2A.Z Controls a Critical Chromatin Remodeling Step Required for DNA Double-Strand Break Repair

    Ye Xu;Marina K. Ayrapetov;Chang Xu;Ozge Gursoy-Yuzugullu

  • Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay.

    K E Rosenzweig;M B Youmell;S T Palayoor;B D Price

  • An essential role of NFκB in tyrosine kinase signaling of p38 MAP kinase regulation of myocardial adaptation to ischemia

    Nilanjana Maulik;Motoaki Sato;Brendan D. Price;Dipak K. Das

  • Increases in Sequence Specific DNA Binding by p53 following Treatment with Chemotherapeutic and DNA Damaging Agents

    R B Tishler;S K Calderwood;C N Coleman;B D Price

  • Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation.

    Yingli Sun;Xiaofeng Jiang;Shujuan Chen;Brendan D. Price

  • Tip60: connecting chromatin to DNA damage signaling.

    Yingli Sun;Xiaofeng Jiang;Brendan D. Price

  • Gadd45 and Gadd153 messenger RNA levels are increased during hypoxia and after exposure of cells to agents which elevate the levels of the glucose-regulated proteins.

    Brendan D. Price;Stuart K. Calderwood

  • The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

    Ye Xu;Yingli Sun;Xiaofeng Jiang;Marina Ayrapetov

  • Chromatin dynamics and the repair of DNA double strand breaks.

    Ye Xu;Brendan D. Price

  • The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage.

    Brendan D. Price;Matthew B. Youmell

  • Microtubule-active Drugs Taxol, Vinblastine, and Nocodazole Increase the Levels of Transcriptionally Active p53

    Roy B. Tishler;Diana M. Lamppu;Sonia Park;Brendan D. Price

  • Ca2+ is essential for multistep activation of the heat shock factor in permeabilized cells.

    B D Price;S K Calderwood

Frequent Co-Authors

Stuart K. Calderwood
Stuart K. Calderwood Beth Israel Deaconess Medical Center
Alan Hall
Alan Hall Memorial Sloan Kettering Cancer Center
Alec C. Kimmelman
Alec C. Kimmelman New York University
Christopher J. Marshall
Christopher J. Marshall Institute of Cancer Research
Bruce Demple
Bruce Demple Stony Brook University
Alan D. D'Andrea
Alan D. D'Andrea Dana-Farber Cancer Institute
David B. Donner
David B. Donner University of California, San Francisco
Francis D. Moore
Francis D. Moore Brigham and Women's Hospital
John G. Doench
John G. Doench Broad Institute
William C. Hahn
William C. Hahn Dana-Farber Cancer Institute

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