His primary areas of investigation include GSK-3, Glycogen synthase, Biochemistry, Phosphorylation and Lithium. His GSK-3 research is within the category of Cell biology. Richard S. Jope is researching Glycogen synthase as part of the investigation of Endocrinology and Internal medicine.
His Biochemistry research includes themes of Choline acetyltransferase and Acetylcholine. As a part of the same scientific family, Richard S. Jope mostly works in the field of Phosphorylation, focusing on Hippocampus and, on occasion, Ketamine, Psychopharmacology, Hyperphosphorylation, Insulin and Streptozotocin. His Lithium research is multidisciplinary, relying on both Mood stabilizer, Status epilepticus and Neuroprotection, Drug, Pharmacology.
Richard S. Jope spends much of his time researching Internal medicine, Endocrinology, GSK-3, Glycogen synthase and Cell biology. His work focuses on many connections between Endocrinology and other disciplines, such as Inositol, that overlap with his field of interest in Phospholipid. In his study, Status epilepticus is strongly linked to Pharmacology, which falls under the umbrella field of GSK-3.
His Glycogen synthase study which covers Fragile X syndrome that intersects with Knockout mouse. His research in Cell biology intersects with topics in Apoptosis and Molecular biology. Richard S. Jope focuses mostly in the field of Lithium, narrowing it down to matters related to Mood stabilizer and, in some cases, Mood disorders.
The scientist’s investigation covers issues in GSK-3, Glycogen synthase, Endocrinology, Internal medicine and Neuroscience. His study in GSK-3 focuses on GSK3B in particular. His Glycogen synthase research integrates issues from Long-term potentiation, Receptor, Fragile X syndrome and Pharmacology.
His studies in Endocrinology integrate themes in fields like Protein kinase B, Methylphenidate and Learned helplessness. His Internal medicine research is multidisciplinary, incorporating elements of Transgene and Premovement neuronal activity. His Neuroscience research incorporates elements of Multiple sclerosis, Lithium and Biochemistry.
Richard S. Jope mainly focuses on GSK-3, Signal transduction, Glycogen synthase, Phosphorylation and Learned helplessness. His study in the fields of GSK3B under the domain of GSK-3 overlaps with other disciplines such as XBP1. His studies deal with areas such as Cancer research, Unfolded protein response, Transcription Factor CHOP, ATF4 and Kinase as well as Signal transduction.
His research investigates the connection between Glycogen synthase and topics such as Neuroscience that intersect with issues in G protein-coupled receptor. The various areas that Richard S. Jope examines in his Phosphorylation study include Receptor, Serotonin reuptake inhibitor, Serotonin and Serotonin Uptake Inhibitors. His research on Learned helplessness also deals with topics like
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The glamour and gloom of glycogen synthase kinase-3.
Richard S Jope;Gail V.W Johnson.
Trends in Biochemical Sciences (2004)
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling.
Carol A Grimes;Richard S Jope.
Progress in Neurobiology (2001)
Toll-like receptor—mediated cytokine production is differentially regulated by glycogen synthase kinase 3
Michael Martin;Kunal Rehani;Richard S Jope;Suzanne M Michalek.
Nature Immunology (2005)
Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
Eleonore Beurel;Steven F. Grieco;Richard S. Jope.
Pharmacology & Therapeutics (2015)
Glycogen Synthase Kinase-3 (GSK3): Inflammation, Diseases, and Therapeutics
Richard S. Jope;Christopher J. Yuskaitis;Eléonore Beurel.
Neurochemical Research (2007)
The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways
Eléonore Beurel;Richard S. Jope.
Progress in Neurobiology (2006)
Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes
Richard S Jope.
Trends in Pharmacological Sciences (2003)
Regulation of Akt and glycogen synthase kinase-3β phosphorylation by sodium valproate and lithium
Patrizia De Sarno;Xiaohua Li;Richard S. Jope.
CREB DNA binding activity is inhibited by glycogen synthase kinase-3β and facilitated by lithium
Carol A. Grimes;Richard S. Jope.
Journal of Neurochemistry (2001)
Anti-bipolar therapy: mechanism of action of lithium.
R S Jope.
Molecular Psychiatry (1999)
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