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Darren P. Baker

Darren P. Baker

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
10557
World Ranking
17940
National Ranking
7341

Overview

Darren P. Baker is affiliated with Sanofi in the United States and primarily conducts research in the field of Medicine. Their work spans several subfields, notably Pathology and Forensic Medicine, Rheumatology, Immunology, Neurology, and Molecular Biology. The scientist's research focuses on topics including Multiple Sclerosis Research Studies, Systemic Lupus Erythematosus Research, T-cell and B-cell Immunology, Systemic Sclerosis and Related Diseases, Rheumatoid Arthritis Research and Therapies, Peripheral Neuropathies and Disorders, and Single-cell and spatial transcriptomics.

Their recent publications highlight ongoing investigation into multiple sclerosis and autoimmune conditions. Key papers by Darren P. Baker include:

  • "Alemtuzumab outcomes by age: Post hoc analysis from the randomized CARE-MS studies over 8 years" (2020), published in Multiple Sclerosis and Related Disorders
  • "Proportion of alemtuzumab-treated patients converting from relapsing-remitting multiple sclerosis to secondary progressive multiple sclerosis over 6 years" (2020), published in Multiple Sclerosis Journal - Experimental Translational and Clinical
  • "Efficacy and Safety of Teriflunomide in Multiple Sclerosis across Age Groups: Analysis from Pooled Pivotal and Real-world Studies" (2021), published in Journal of Central Nervous System Disease
  • "Endocrine and multiple sclerosis outcomes in patients with autoimmune thyroid events in the alemtuzumab CARE-MS studies" (2023), published in Multiple Sclerosis Journal - Experimental Translational and Clinical
  • "The contribution of anthropology to the study of Open Dialogue: ethnographic research methods and opportunities" (2023), published in Frontiers in Psychology

Darren P. Baker frequently publishes in venues such as Multiple Sclerosis Journal - Experimental Translational and Clinical, Neurology, Research Square (Research Square), Multiple Sclerosis and Related Disorders, and Frontiers in Psychology.

The scientist collaborates regularly with colleagues including Nadia Daizadeh, Elizabeth M. Poole, David Margolin, Tjalf Ziemssen, and Samuel F. Hunter, with multiple joint publications reflecting ongoing partnerships in their research areas.

Best Publications

  • Function of Mitochondrial Stat3 in Cellular Respiration

    Joanna Wegrzyn;Ramesh Potla;Yong Joon Chwae;Naresh B.V. Sepuri

  • Identification of a palmitic acid-modified form of human Sonic hedgehog.

    R. B. Pepinsky;Chenhui Zeng;Dingyi Wen;P. Rayhorn

  • Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation

    G Bhardwaj;B Murdoch;D Wu;D P Baker

  • The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors

    Roberto Pola;Leona E. Ling;Marcy Silver;Michael J. Corbley

  • Improved pharmacokinetic properties of a polyethylene glycol-modified form of interferon-beta-1a with preserved in vitro bioactivity.

    R B Pepinsky;D J LePage;A Gill;A Chakraborty

  • Comparative biological responses to human Sonic, Indian, and Desert hedgehog.

    Suji Pathi;Sylvia Pagan-Westphal;Darren P Baker;Ellen A Garber

  • Role of the Akt pathway in mRNA translation of interferon-stimulated genes.

    Surinder Kaur;Antonella Sassano;Blazej Dolniak;Sonali Joshi

  • Regionalization within the mammalian telencephalon is mediated by changes in responsiveness to Sonic Hedgehog.

    Jhumku D. Kohtz;Darren P. Baker;Giorgio Corte;Gord Fishell

  • IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity.

    Stephen G. Maher;Faruk Sheikh;Anthony J. Scarzello;Ana L. Romero-Weaver

  • Enhanced potency of human Sonic hedgehog by hydrophobic modification.

    Frederick R. Taylor;Dingyi Wen;Ellen A. Garber;Amie N. Carmillo

  • Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling.

    Danlin Jia;Ramtin Rahbar;Renee W. Y. Chan;Suki M. Y. Lee

  • Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases.

    Douglas J. Marcotte;Yu-Ting Liu;Robert M. Arduini;Catherine A. Hession

  • Cutting Edge: Role of STAT1, STAT3, and STAT5 in IFN-αβ Responses in T Lymphocytes

    Yoshinari Tanabe;Takeaki Nishibori;Leon Su;Robert M. Arduini

  • N-Terminally PEGylated Human Interferon-β-1a with Improved Pharmacokinetic Properties and in Vivo Efficacy in a Melanoma Angiogenesis Model§

    Darren P. Baker;Edward Y. Lin;KoChung Lin;Maria Pellegrini

  • Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment.

    Thomas Blank;Claudia N. Detje;Alena Spieß;Nora Hagemeyer

  • Regulatory Effects of Mammalian Target of Rapamycin-activated Pathways in Type I and II Interferon Signaling

    Surinder Kaur;Lakhvir Lal;Antonella Sassano;Beata Majchrzak-Kita

  • Site-specific ubiquitination exposes a linear motif to promote interferon-α receptor endocytosis

    K.G. Suresh Kumar;Hervé Barriere;Christopher J. Carbone;Jianghuai Liu

  • Viral Infection Augments Nod1/2 Signaling to Potentiate Lethality Associated with Secondary Bacterial Infections

    Yun Gi Kim;Jong Hwan Park;Thornik Reimer;Darren P. Baker

  • N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons.

    Jhumku D. Kohtz;Hae Young Lee;Nicholas Gaiano;Joshua Segal

  • LDL, scavenger, and beta-VLDL receptors on aortic endothelial cells.

    D P Baker;B J Van Lenten;A M Fogelman;P A Edwards

Frequent Co-Authors

Serge Y. Fuchs
Serge Y. Fuchs University of Pennsylvania
R. Blake Pepinsky
R. Blake Pepinsky Biogen (United States)
Eleanor N. Fish
Eleanor N. Fish University of Toronto
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University
Andrew C. Larner
Andrew C. Larner Virginia Commonwealth University
Michael David
Michael David University of Pennsylvania
Dennis J. Stuehr
Dennis J. Stuehr Cleveland Clinic Lerner College of Medicine
Jozef Dulak
Jozef Dulak Jagiellonian University
Constantinos Koumenis
Constantinos Koumenis University of Pennsylvania
Hallgeir Rui
Hallgeir Rui Medical College of Wisconsin

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