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Biology and Biochemistry

D-Index
65
Citations
11824
World Ranking
9380
National Ranking
4134

Overview

Hallgeir Rui is affiliated with the Medical College of Wisconsin in the United States and has contributed extensively to research in medicine, with a particular focus on oncology and molecular biology. Their work encompasses a significant number of publications that span various subfields such as oncology, pulmonary and respiratory medicine, cancer research, and infectious diseases.

The scientist's research topics include:

  • Advanced Breast Cancer Therapies
  • HER2/EGFR in Cancer Research
  • COVID-19 Clinical Research Studies
  • Breast Cancer Treatment Studies
  • Cancer Immunotherapy and Biomarkers
  • Cancer Treatment and Pharmacology
  • Long-Term Effects of COVID-19

Hallgeir Rui has coauthored numerous papers with frequent collaborators, including Yunguang Sun, Inna Chervoneva, Amy R. Peck, Julie M. Jorns, and Lubna N. Chaudhary. These collaborations reflect ongoing partnerships within the biomedical research community.

Their research has been published in several key scientific venues, with multiple papers appearing in:

  • Cancer Research
  • Cell Reports
  • Oncogene
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Endocrinology

Representative recent publications include:

  • RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site (2021), published in Cell Reports
  • Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth (2021), published in Cancer Research
  • Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells (2021), published in Nature Communications
  • Breast Cancer and Prolactin - New Mechanisms and Models (2022), published in Endocrinology
  • Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis (2020), published in Oncogene

The bulk of Hallgeir Rui's publication record covers 127 papers in medicine and 75 in biochemistry, genetics, and molecular biology, reflecting interdisciplinary expertise. Among subfields, oncology and molecular biology dominate with 48 and 42 publications respectively, alongside works in pulmonary and respiratory medicine, cancer research, and infectious diseases.

Best Publications

  • Activation of receptor-associated tyrosine kinase JAK2 by prolactin

    Hallgeir Rui;Robert A. Kirken;William L. Farrar

  • Analysis of miR-195 and miR-497 expression, regulation and role in breast cancer

    Dan Li;Yulan Zhao;Changxing Liu;Xiaona Chen

  • Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation.

    Philip M. Grimley;Fan Dong;Hallgeir Rui

  • Signal Transducer and Activator of Transcription-5 Activation and Breast Cancer Prognosis

    Marja T. Nevalainen;Jianwu Xie;Joachim Torhorst;Lukas Bubendorf

  • Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells

    Ahmed S Sultan;Jianwu Xie;Matthew J LeBaron;Erica L Ealley

  • Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment

    Kanstantsin V. Katlinski;Jun Gui;Yuliya V. Katlinskaya;Angelíca Ortiz

  • Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580

    Luis DaSilva;Hallgeir Rui;Rebecca A. Erwin;O.M. Zack Howard

  • RB-pathway disruption in breast cancer: Differential association with disease subtypes, disease-specific prognosis and therapeutic response

    Adam Ertel;Jeffry L. Dean;Hallgeir Rui;Chengbao Liu

  • Impaired Alveologenesis and Maintenance of Secretory Mammary Epithelial Cells in Jak2 Conditional Knockout Mice

    Kay Uwe Wagner;Andrea Krempler;Aleata A. Triplett;Yongyue Qi

  • Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors

    L. Dasilva;O. M. Z. Howard;H. Rui;R. A. Kirken

  • Differential Control of the Phosphorylation State of Proline-juxtaposed Serine Residues Ser725 of Stat5a and Ser730 of Stat5b in Prolactin-sensitive Cells

    Hiroko Yamashita;Jun Xu;Rebecca A. Erwin;Rebecca A. Erwin;William L. Farrar

  • Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression.

    Kay Uwe Wagner;Hallgeir Rui

  • Inhibition of Transcription Factor Stat5 Induces Cell Death of Human Prostate Cancer Cells

    Tommi J. Ahonen;Tommi J. Ahonen;Jianwu Xie;Matthew J. LeBaron;Jianqiong Zhu

  • JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization

    Hallgeir Rui;Jean Jacques Lebrun;Robert A. Kirken;Paul A. Kelly

  • Prolactin receptor triggering. Evidence for rapid tyrosine kinase activation.

    H Rui;J Y Djeu;G A Evans;P A Kelly

  • Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer

    Agnieszka K. Witkiewicz;Abhijit Dasgupta;Katherine H. Nguyen;Chengbao Liu

  • Effects of growth hormone and prolactin immune development and function

    William J. Murphy;Hallgeir Rui;Dan L. Longo

  • Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless.

    R A Erwin;R A Kirken;M G Malabarba;W L Farrar

  • An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles.

    Angelica Ortiz;Jun Gui;Farima Zahedi;Pengfei Yu

  • Function associated with IL-2 receptor-beta on human neutrophils. Mechanism of activation of antifungal activity against Candida albicans by IL-2.

    J. Y. Djeu;Jin Hong Liu;Sheng Wei;Hallgeir Rui

Frequent Co-Authors

William L. Farrar
William L. Farrar National Institutes of Health
Richard G. Pestell
Richard G. Pestell The Wistar Institute
Serge Y. Fuchs
Serge Y. Fuchs University of Pennsylvania
Michael P. Lisanti
Michael P. Lisanti University of Salford
Agnieszka K. Witkiewicz
Agnieszka K. Witkiewicz Roswell Park Cancer Institute
Chenguang Wang
Chenguang Wang Johns Hopkins University
David G. Gorenstein
David G. Gorenstein The University of Texas Health Science Center at Houston
Federica Sotgia
Federica Sotgia University of Salford
Kongming Wu
Kongming Wu Zhengzhou University
Paul L. Auer
Paul L. Auer Medical College of Wisconsin

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