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Andres Jäschke

Andres Jäschke

D-Index & Metrics

Chemistry

D-Index
45
Citations
7066
World Ranking
16489
National Ranking
1194

Overview

Andres Jäschke is affiliated with Heidelberg University in Germany and has contributed extensively to research in biochemistry, genetics, and molecular biology. Their work primarily focuses on molecular biology, materials chemistry, cellular and molecular neuroscience, organic chemistry, and biophysics.

The main topics addressed in their research include:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Advanced biosensing and bioanalysis techniques
  • Photochromic and fluorescence chemistry
  • Photoreceptor and optogenetics research
  • RNA interference and gene delivery
  • RNA research and splicing

Jäschke has published papers in several scientific journals, with frequent appearances in bioRxiv (Cold Spring Harbor Laboratory), Angewandte Chemie International Edition, Angewandte Chemie, Chemical Communications, and Nature Communications.

Several prominent co-authors have collaborated with Jäschke, including Murat Sünbül, Theresa Kolmar, G. Ulrich Nienhaus, Katharina Höfer, and Simon M. Büllmann.

Notable recent publications include:

  • Super-resolution RNA imaging using a rhodamine-binding aptamer with fast exchange kinetics, 2021, Nature Biotechnology
  • Fast-exchanging spirocyclic rhodamine probes for aptamer-based super-resolution RNA imaging, 2023, Nature Communications
  • Avidity-based bright and photostable light-up aptamers for single-molecule mRNA imaging, 2023, Nature Chemical Biology
  • A Color-Shifting Near-Infrared Fluorescent Aptamer-Fluorophore Module for Live-Cell RNA Imaging, 2021, Angewandte Chemie International Edition
  • A viral ADP-ribosyltransferase attaches RNA chains to host proteins, 2023, Nature

Best Publications

  • A small catalytic RNA motif with Diels-Alderase activity.

    Burckhard Seelig;Andres Jäschke

  • NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs

    Hana Cahová;Marie-Luise Winz;Katharina Höfer;Gabriele Nübel

  • Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation

    Alexander Serganov;Sonja Keiper;Lucy Malinina;Valentina Tereshko

  • Post-synthetic modification of DNA by inverse-electron-demand Diels-Alder reaction.

    Juliane Schoch;Manfred Wiessler;Andres Jäschke

  • The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent.

    Ralf Hauenschild;Lyudmil Tserovski;Katharina Schmid;Kathrin Thuring

  • Enantioselective Ribozyme Catalysis of a Bimolecular Cycloaddition Reaction

    Burckhard Seelig;Sonja Keiper;Friedrich Stuhlmann;Andres Jäschke

  • Site-specific terminal and internal labeling of RNA by poly(A) polymerase tailing and copper-catalyzed or copper-free strain-promoted click chemistry

    Marie-Luise Winz;Ayan Samanta;Dirk Benzinger;Andres Jäschke

  • SiRA: A Silicon Rhodamine-Binding Aptamer for Live-Cell Super-Resolution RNA Imaging

    Regina Wirth;Peng Gao;G. Ulrich Nienhaus;Murat Sunbul

  • Selection of ribozymes that catalyse multiple-turnover Diels-Alder cycloadditions by using in vitro compartmentalization.

    Jeremy J. Agresti;Bernard T. Kelly;Andres Jäschke;Andrew D. Griffiths

  • Contact-Mediated Quenching for RNA Imaging in Bacteria with a Fluorophore-Binding Aptamer

    Murat Sunbul;Andres Jäschke

  • Site-Specific One-Pot Dual Labeling of DNA by Orthogonal Cycloaddition Chemistry

    Juliane Schoch;Markus Staudt;Ayan Samanta;Manfred Wiessler

  • Allylic Amination by a DNA–Diene–Iridium(I) Hybrid Catalyst

    Pierre Fournier;Roberto Fiammengo;Andres Jäschke

  • Time-resolved NMR studies of RNA folding.

    Boris Fürtig;Janina Buck;Vijayalaxmi Manoharan;Wolfgang Bermel

  • Characterization of an RNA active site: interactions between a Diels-Alderase ribozyme and its substrates and products.

    Friedrich Stuhlmann;Andres Jäschke

  • Nucleoside‐Based Diarylethene Photoswitches and Their Facile Incorporation into Photoswitchable DNA

    Hana Cahová;Andres Jäschke

  • Reversibly Photoswitchable Nucleosides: Synthesis and Photochromic Properties of Diarylethene-Functionalized 7-Deazaadenosine Derivatives

    Marco Singer;Andres Jäschke

  • Super-resolution RNA imaging using a rhodamine-binding aptamer with fast exchange kinetics

    Murat Sunbul;Jens Lackner;Annabell Martin;Daniel Englert

  • Synthesis and properties of oligodeoxyribonucleotide—polyethylene glycol conjugates

    Andres Jäschke;Jens P. Fürste;Eckhard Nordhoff;Franz Hillenkamp

  • Detection of small organic analytes by fluorescing molecular switches.

    Christian Frauendorf;Andres Jäschke

  • Artificial ribozymes and deoxyribozymes.

    Andres Jäschke

  • Structural basis for Diels-Alder ribozyme catalyzed carbon-carbon bond formation

    A. Jaschke;A. Serganov;S. Keiper;L. Malinina

Frequent Co-Authors

G. Ulrich Nienhaus
G. Ulrich Nienhaus Karlsruhe Institute of Technology
Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Mark Helm
Mark Helm Johannes Gutenberg University of Mainz
Zbigniew Dauter
Zbigniew Dauter Brookhaven National Laboratory
Michael Müller
Michael Müller Forschungszentrum Jülich
Martin Oestreich
Martin Oestreich Technical University of Berlin
Markus Albrecht
Markus Albrecht RWTH Aachen University
Volker A. Erdmann
Volker A. Erdmann Freie Universität Berlin
Anh Tuân Phan
Anh Tuân Phan Nanyang Technological University
Manfred Wiessler
Manfred Wiessler German Cancer Research Center

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