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Chemistry

D-Index
44
Citations
7029
World Ranking
16866
National Ranking
1221

Overview

Manfred Wiessler is affiliated with the German Cancer Research Center in Germany. Their academic profile reflects involvement within a prominent institution dedicated to cancer research.

While specific details on publications, including recent papers, co-authors, and frequent publication venues, are not available, the affiliation suggests a career centered around biomedical research within oncology and related fields.

No listed main fields of study, subfields, or detailed topics of work are provided. There is also no information on book publications or awards conferred. This absence of specific data limits further elaboration on research focus areas or scholarly contributions.

No records indicate whether the scientist has won any awards, published notable works, or collaborated frequently with other researchers. The lack of citation data and publication metrics suggests a profile not currently supplemented by a detailed bibliometric footprint accessible here.

Manfred Wiessler is not deceased and may still be active in their research capacity or related academic activities at the German Cancer Research Center.

Best Publications

  • Amino Acids for Diels–Alder Reactions in Living Cells

    Tilman Plass;Sigrid Milles;Christine Koehler;Jędrzej Szymański

  • 32P-post labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy

    C A Bieler;M Stiborova;M Wiessler;J P Cosyns

  • Post-synthetic modification of DNA by inverse-electron-demand Diels-Alder reaction.

    Juliane Schoch;Manfred Wiessler;Andres Jäschke

  • The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts.

    Marie Stiborová;Christian A. Bieler;Manfred Wiessler;Eva Frei

  • Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation

    Annika Borrmann;Sigrid Milles;Tilman Plass;Jan Dommerholt

  • The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide.

    Marie Stiborová;Jan Sejbal;Lucie Borek-Dohalská;Dagmar Aimová

  • Aristolochic acid binds covalently to the exocyclic amino group of purine nucleotides in DNA

    Wolfgang Pfau;Heinz H. Schmeiser;Manfred Wiessler

  • Human Enzymes Involved in the Metabolic Activation of Carcinogenic Aristolochic Acids: Evidence for Reductive Activation by Cytochromes P450 1A1 and 1A2

    Marie Stiborová;Eva Frei;Manfred Wiessler;Heinz H. Schmeiser

  • D-19575--a sugar-linked isophosphoramide mustard derivative exploiting transmembrane glucose transport.

    J Pohl;B Bertram;P Hilgard;M R Nowrousian

  • Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.

    Marie Stiborová;Eva Frei;Bruno Sopko;Klára Sopková

  • Biodegradability of antineoplastic compounds in screening tests: influence of glucosidation and of stereochemistry.

    K Kümmerer;A Al-Ahmad;B Bertram;M Wießler

  • Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

    Marie Stiborová;Eva Frei;Petr Hodek;Manfred Wiessler

  • Site-Specific One-Pot Dual Labeling of DNA by Orthogonal Cycloaddition Chemistry

    Juliane Schoch;Markus Staudt;Ayan Samanta;Manfred Wiessler

  • Characterization of DNA adducts formed by aristolochic acids in the target organ (forestomach) of rats by 32P-postlabelling analysis using different chromatographic procedures

    Stiborová M;Fernando Rc;Schmeiser Hh;Frei E

  • Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy

    Marie Stiborová;Eva Frei;Bruno Sopko;Manfred Wiessler

  • Identification and mutagenicity of metabolites of aristolochic acid formed by rat liver

    H.H. Schmeiser;B.L. Pool;M. Wiessler

  • 32P-postlabelling analysis of the DNA adducts formed by aristolochic acid I and II

    Wolfgang Pfau;Heinz H. Schmeiser;Manfred Wiessler

  • Inverse-electron-demand Diels-Alder reaction as a highly efficient chemoselective ligation procedure: synthesis and function of a BioShuttle for temozolomide transport into prostate cancer cells.

    Rüdiger Pipkorn;Waldemar Waldeck;Bernd Didinger;Mario Koch

  • Comparison of DNA adduct formation by aristolochic acids in various in vitro activation systems by 32P-post-labelling : evidence for reductive activation by peroxidases

    H H Schmeiser;E Frei;M Wiessler;M Stiborova

  • Transport of the new chemotherapeutic agent β-d-glucosylisophosphoramide mustard (D-19575) into tumor cells is mediated by the Na+-d-glucose cotransporter SAAT1

    Maike Veyhl;Katharina Wagner;Christopher Volk;Valentin Gorboulev

  • DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by (32)P-postlabeling.

    Volker M. Arlt;Christian A. Bieler;Walter Mier;Manfred Wiessler

  • Subacute NO generation induced by Alzheimer’s β-amyloid in the living brain: reversal by inhibition of the inducible NO synthase

    K. Ishii;F. Muelhauser;U. Liebl;M. Picard

  • DNA adduct formation by the anticancer drug ellipticine in rats determined by 32P postlabeling.

    Marie Stiborová;Andrea Breuer;Dagmar Aimová;Martina Stiborová-Rupertová

  • Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans.

    Marie Stiborova;Martina Stiborova-Rupertova;Lucie Borek-Dohalska;Manfred Wiessler

Frequent Co-Authors

Eva Frei
Eva Frei Charles University
Heinz H. Schmeiser
Heinz H. Schmeiser German Cancer Research Center
Marie Stiborová
Marie Stiborová Charles University
Walter Mier
Walter Mier University Hospital Heidelberg
Marek Los
Marek Los Silesian University of Technology
Konrad Beyreuther
Konrad Beyreuther Heidelberg University
Volker M. Arlt
Volker M. Arlt King's College London
Simone Fulda
Simone Fulda Goethe University Frankfurt
Klaus-Michael Debatin
Klaus-Michael Debatin University of Ulm
Peter Schmezer
Peter Schmezer German Cancer Research Center

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