Elizabeth Sinclair

Overview

Best Publications

• T Cell Activation Is Associated with Lower CD4+ T Cell Gains in Human Immunodeficiency Virus-Infected Patients with Sustained Viral Suppression during Antiretroviral Therapy

  Peter W Hunt;Jeffrey N Martin;Elizabeth Sinclair;Barry Bredt

  835
  Citations

• Relationship between T Cell Activation and CD4+ T Cell Count in HIV-Seropositive Individuals with Undetectable Plasma HIV RNA Levels in the Absence of Therapy

  Peter W. Hunt;Jason Brenchley;Elizabeth Sinclair;Joseph M. McCune

  809
  Citations

• Plasma Levels of Bacterial DNA Correlate with Immune Activation and the Magnitude of Immune Restoration in Persons with Antiretroviral-Treated HIV Infection

  Wei Jiang;Michael M. Lederman;Peter Hunt;Scott F. Sieg

  738
  Citations

• HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.

  Sergio Serrano-Villar;Talia Sainz;Sulggi A. Lee;Peter W. Hunt

  736
  Citations

• Gut Epithelial Barrier Dysfunction and Innate Immune Activation Predict Mortality in Treated HIV Infection

  Peter W. Hunt;Elizabeth Sinclair;Benigno Rodriguez;Carey Shive

  574
  Citations

• Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.

  Julian H. Elliott;Fiona Wightman;Ajantha Solomon;Khader Ghneim

  565
  Citations

• Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance.

  Jue Lin;Elissa Epel;Joshua Cheon;Candyce Kroenke

  481
  Citations

• Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells.

  Dennis J. Hartigan-O'Connor;Chungkee Poon;Elizabeth Sinclair;Joseph M. McCune

  480
  Citations

• CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART

  Rémi Fromentin;Wendy Bakeman;Mariam B. Lawani;Gabriela Khoury;Gabriela Khoury

  441
  Citations

• Use of overlapping peptide mixtures as antigens for cytokine flow cytometry

  Holden T Maecker;Holli S Dunn;Maria A Suni;Elham Khatamzas;Elham Khatamzas

  437
  Citations

• Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants

  Bonnie Hiener;Bethany A. Horsburgh;John-Sebastian Eden;Kirston Barton

  391
  Citations

• Valganciclovir Reduces T Cell Activation in HIV-Infected Individuals With Incomplete CD4+ T Cell Recovery on Antiretroviral Therapy

  Peter W. Hunt;Jeffrey N. Martin;Elizabeth Sinclair;Lorrie Epling

  387
  Citations

• Antiretroviral Therapy Initiated Within 6 Months of HIV Infection Is Associated With Lower T-Cell Activation and Smaller HIV Reservoir Size

  Vivek Jain;Wendy Hartogensis;Peter Bacchetti;Peter W. Hunt

  383
  Citations

• T Cell Activation and Senescence Predict Subclinical Carotid Artery Disease in HIV-Infected Women

  Robert C. Kaplan;Elizabeth Sinclair;Alan L. Landay;Nell Lurain

  349
  Citations

• Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient

  Steven A. Yukl;Eli Boritz;Michael Busch;Christopher Bentsen

  344
  Citations

• Differences in HIV Burden and Immune Activation within the Gut of HIV-Positive Patients Receiving Suppressive Antiretroviral Therapy

  Steven A. Yukl;Steven A. Yukl;Sara Gianella;Sara Gianella;Elizabeth Sinclair;Lorrie Epling

  334
  Citations

• Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses.

  Priscilla Y Hsue;Peter W Hunt;Elizabeth Sinclair;Barry Bredt

  329
  Citations

• The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time.

  Lina Josefsson;Susanne von Stockenstrom;Nuno R. Faria;Elizabeth Sinclair

  318
  Citations

• HLA Class I-Restricted T-Cell Responses May Contribute to the Control of Human Immunodeficiency Virus Infection, but Such Responses Are Not Always Necessary for Long-Term Virus Control

  Brinda Emu;Elizabeth Sinclair;Hiroyu Hatano;April Ferre

  311
  Citations

• Phenotypic, Functional, and Kinetic Parameters Associated with Apparent T-Cell Control of Human Immunodeficiency Virus Replication in Individuals with and without Antiretroviral Treatment

  Brinda Emu;Elizabeth Sinclair;David Favre;Walter J. Moretto

  306
  Citations