What is he best known for?
The fields of study he is best known for:
- Organic chemistry
- Enzyme
- DNA
J. William Lown focuses on Stereochemistry, DNA, Biochemistry, Lexitropsin and Photochemistry.
His primary area of study in Stereochemistry is in the field of Moiety.
The Moiety study combines topics in areas such as Nucleic acid and Quinone.
His study in DNA is interdisciplinary in nature, drawing from both Covalent bond, Organic chemistry and Alkylation.
The Lexitropsin study which covers Molecular recognition that intersects with Base pair.
His Photochemistry research is multidisciplinary, incorporating elements of Singlet oxygen, Reactive oxygen species, Hydrogen peroxide and Hydroxyl radical.
His most cited work include:
- Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents. (239 citations)
- The mechanism of the bleomycin-induced cleavage of DNA. (217 citations)
- Synthetic DNA minor groove-binding drugs. (189 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Stereochemistry, DNA, Organic chemistry, Lexitropsin and Biochemistry.
His study in Stereochemistry focuses on Moiety in particular.
His study looks at the relationship between Moiety and topics such as Quinone, which overlap with Photochemistry.
His studies in DNA integrate themes in fields like Cleavage, Alkylation, Nucleic acid, Covalent bond and Bond cleavage.
In his study, Polyamide is strongly linked to Combinatorial chemistry, which falls under the umbrella field of Organic chemistry.
His Lexitropsin research includes elements of Crystallography, Proton NMR, Molecular recognition and DNA Minor Groove Binding.
He most often published in these fields:
- Stereochemistry (54.84%)
- DNA (27.82%)
- Organic chemistry (15.73%)
What were the highlights of his more recent work (between 1996-2016)?
- Stereochemistry (54.84%)
- Conjugate (9.27%)
- Organic chemistry (15.73%)
In recent papers he was focusing on the following fields of study:
J. William Lown mainly investigates Stereochemistry, Conjugate, Organic chemistry, Combinatorial chemistry and Polyamide.
He combines subjects such as DNA, A-DNA, Methylene, Cytotoxicity and Lexitropsin with his study of Stereochemistry.
DNA is a subfield of Biochemistry that he tackles.
His Lexitropsin research incorporates elements of Thymine, Topoisomerase and Nucleic acid.
His research in Combinatorial chemistry tackles topics such as Benzodiazepine which are related to areas like Nitro and Antitumor Antibiotics.
His Polyamide research is multidisciplinary, incorporating elements of Imidazole, Pyrrole, Distamycin, Solid-phase synthesis and Thiazole.
Between 1996 and 2016, his most popular works were:
- Synthetic DNA minor groove-binding drugs. (189 citations)
- Anticancer, Anti-inflammatory and Analgesic Activity Evaluation of Heterocyclic Compounds Synthesized by the Reaction of 4-Isothiocyanato-4-methylpentan-2-one with Substituted o-Phenylenediamines, o-Diaminopyridine and (Un)Substituted o (108 citations)
- Preclinical Assessment of Hypocrellin B and Hypocrellin B Derivatives as Sensitizers for Photodynamic Therapy of Cancer: Progress Update (92 citations)
In his most recent research, the most cited papers focused on:
- Organic chemistry
- Enzyme
- DNA
J. William Lown spends much of his time researching Stereochemistry, Biochemistry, Lexitropsin, Conjugate and DNA.
His Stereochemistry study incorporates themes from Amino acid, Biocatalysis, Base pair, Cytotoxicity and Chemical synthesis.
His study looks at the relationship between Biochemistry and fields such as Cell culture, as well as how they intersect with chemical problems.
His Lexitropsin research is multidisciplinary, relying on both Carzelesin, Thymine and Topoisomerase.
His work in the fields of DNA, such as Netropsin, Adozelesin and Anthramycin, overlaps with other areas such as DAPI.
J. William Lown has included themes like In vitro, Pyrrole and Polyamide in his Imidazole study.
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