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D-Index & Metrics

Chemistry

D-Index
86
Citations
23472
World Ranking
2586
National Ranking
902

Overview

W. David Wilson is affiliated with Georgia State University in the United States. Their research primarily falls within the broad field of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Molecular Biology. Other subfields of study include Spectroscopy, Organic Chemistry, Plant Science, and Public Health, Environmental and Occupational Health.

The scientist's main research topics cover areas such as DNA and Nucleic Acid Chemistry, RNA and protein synthesis mechanisms, and advanced biosensing and bioanalysis techniques. Additional topics include RNA Interference and Gene Delivery, Genomics and Chromatin Dynamics, Cancer therapeutics and mechanisms, and Molecular Sensors and Ion Detection.

W. David Wilson has published multiple papers in a variety of venues. Frequent publication venues include UNC Libraries, ACS Medicinal Chemistry Letters, European Journal of Medicinal Chemistry, OPAL (Open@LaTrobe) at La Trobe University, and Nature Communications.

Notable recent papers include:

  • Structure of an RNA G-quadruplex from the West Nile virus genome (2024, Nature Communications)
  • DNA selection by the master transcription factor PU.1 (2023, Cell Reports)
  • Engineered modular heterocyclic-diamidines for sequence-specific recognition of mixed AT/GC base pairs at the DNA minor groove (2021, Chemical Science)
  • Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models (2020, ACS Medicinal Chemistry Letters)
  • Substituted Naphthalenediimide Compounds Bind Selectively to Two Human Quadruplex Structures with Parallel Topology (2020, ACS Medicinal Chemistry Letters)

Frequent co-authors in their research include Ananya Paul, Abdelbasset A. Farahat, Gregory M.K. Poon, J. Ross Terrell, and David W. Boykin. Collaborative efforts with these researchers have resulted in numerous publications.

Best Publications

  • A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

    Sung-Wuk Jang;Xia Liu;Manuel Yepes;Kennie R. Shepherd

  • The search for structure-specific nucleic acid-interactive drugs: effects of compound structure on RNA versus DNA interaction strength.

    W. D. Wilson;L. Ratmeyer;Min Zhao;L. Strekowski

  • Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure.

    Evonne M. Rezler;Jeyaprakashnarayanan Seenisamy;Sridevi Bashyam;Mu Yong Kim

  • Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure.

    Jeyaprakashnarayanan Seenisamy;Sridevi Bashyam;Vijay Gokhale;Hariprasad Vankayalapati

  • DAPI (4',6-diamidino-2-phenylindole) binds differently to DNA and RNA: minor-groove binding at AT sites and intercalation at AU sites.

    Tanious Fa;Veal Jm;Buczak H;Ratmeyer Ls

  • DNA sequence dependent binding modes of 4',6-diamidino-2-phenylindole (DAPI).

    W D Wilson;F A Tanious;H J Barton;R L Jones

  • Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.

    Michael J B Moore;Christoph M Schultes;Javier Cuesta;Francisco Cuenca

  • Antiparasitic compounds that target DNA.

    W. David Wilson;Farial A. Tanious;Amanda Mathis;Denise Tevis

  • Biosensor-surface plasmon resonance: quantitative analysis of small molecule-nucleic acid interactions.

    Binh Nguyen;Farial A. Tanious;W. David Wilson

  • Analyzing Biomolecular Interactions

    W. David Wilson

  • Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.

    R John Harrison;Javier Cuesta;Gianni Chessari;Martin A Read

  • Extended aromatic furan amidino derivatives as anti-Pneumocystis carinii agents.

    Hopkins Kt;Wilson Wd;Bender Bc;McCurdy Dr

  • Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge.

    Elizabeth W. White;Farial Tanious;Mohamed A. Ismail;Anthony P. Reszka

  • Selective recognition of g-quadruplex telomeric DNA by a bis(quinacridine) macrocycle

    Marie-Paule Teulade-Fichou;Carolina Carrasco;Lionel Guittat;Christian Bailly

  • Dicationic diarylfurans as anti-Pneumocystis carinii agents.

    Boykin Dw;Kumar A;Spychala J;Zhou M

  • Dications That Target the DNA Minor Groove: Compound Design and Preparation, DNA Interactions, Cellular Distribution and Biological Activity

    W. David Wilson;Binh Nguyen;Farial A. Tanious;Amanda Mathis

  • G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

    Roberto Simone;Rubika Balendra;Rubika Balendra;Thomas G. Moens;Thomas G. Moens;Elisavet Preza

  • A thermodynamic and structural analysis of DNA minor-groove complex formation.

    Mazur S;Tanious Fa;Ding D;Kumar A

  • Phosphorothioate-modified oligodeoxyribonucleotides. III. NMR and UV spectroscopic studies of the Rp-Rp, Sp-Sp, and Rp-Sp duplexes, [d(GGSAATTCC)]2, derived from diastereomeric O-ethyl phosphorothioates.

    L A LaPlanche;T L James;C Powell;W D Wilson

  • Analysis of cooperativity and ion effects in the interaction of quinacrine with DNA.

    W. David Wilson;Irene G. Lopp

Frequent Co-Authors

David W. Boykin
David W. Boykin Georgia State University
Farial A. Tanious
Farial A. Tanious Georgia State University
Reto Brun
Reto Brun University of Basel
Richard R. Tidwell
Richard R. Tidwell University of North Carolina at Chapel Hill
John A. Hartley
John A. Hartley University College London
Stephen Neidle
Stephen Neidle University College London
Lucjan Strekowski
Lucjan Strekowski Georgia State University
Luigi G. Marzilli
Luigi G. Marzilli Louisiana State University
Gerald Zon
Gerald Zon TriLink BioTechnologies (United States)
Bruce A. Armitage
Bruce A. Armitage Carnegie Mellon University

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