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Chemistry

D-Index
51
Citations
8786
World Ranking
14012
National Ranking
3631

Overview

Bruce A. Armitage is affiliated with Carnegie Mellon University in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology as a key subfield. The scientist's work bridges several interrelated topics, including advanced biosensing and bioanalysis techniques, DNA and nucleic acid chemistry, RNA and protein synthesis mechanisms, RNA interference and gene delivery, bacteriophages and microbial interactions, and nanopore and nanochannel transport studies.

The publication record of Bruce A. Armitage includes contributions to several scientific journals. Frequent publication venues include Biopolymers, ACS Infectious Diseases, Molecules, and Biochemistry. Notably, Biopolymers has hosted multiple publications by the scientist.

  • Targeting a Potential G-Quadruplex Forming Sequence Found in the West Nile Virus Genome by Complementary Gamma-Peptide Nucleic Acid Oligomers (2021, ACS Infectious Diseases)
  • Enhanced Hybridization Selectivity Using Structured GammaPNA Probes (2020, Molecules)
  • Targeting a KRAS i-motif forming sequence by unmodified and gamma-modified peptide nucleic acid oligomers (2022, Biopolymers)
  • Rapid, multiplexed detection of the let-7miRNA family using γPNA amphiphiles in micelle-tagging electrophoresis (2021, Biopolymers)
  • Assembly and Characterization of RNA/DNA Hetero-G-Quadruplexes (2020, Biochemistry)

Among the scientist's frequent collaborators are Srijani Sarkar, April Berlyoung, Gabriela Colón-Roura, Alexander Pearse, and Taylor D. Canady. The frequency of collaboration varies, with multiple collaborations recorded for Srijani Sarkar and April Berlyoung.

Bruce A. Armitage's research topics range widely but consistently emphasize molecular-level investigations of nucleic acids and their interactions. The focus on biosensing and bioanalysis techniques indicates a strong interest in applying biochemical principles to analytical challenges, while works centered on DNA and RNA elaborate on the molecular mechanisms underpinning genetic material behavior. Contributions related to RNA interference, gene delivery, and microbial interactions further expand the scope of their work into applied and mechanistic molecular biology.

Best Publications

  • Photocleavage of Nucleic Acids.

    Bruce Armitage

  • DNA-Templated Formation of a Helical Cyanine Dye J-Aggregate

    Miaomiao Wang;and Gloria L. Silva;Bruce A. Armitage

  • Cyanine Dye–DNA Interactions: Intercalation, Groove Binding, and Aggregation

    Bruce A. Armitage

  • DNA-templated assembly of helical cyanine dye aggregates: a supramolecular chain polymerization.

    Kristen C Hannah;Bruce A Armitage

  • Spontaneous Assembly of Helical Cyanine Dye Aggregates on DNA Nanotemplates

    Jennifer L. Seifert;Rebecca E. Connor;Stuart A. Kushon;Miaomiao Wang

  • Synthesis and Characterization of Conformationally Preorganized, (R)-Diethylene Glycol-Containing γ-Peptide Nucleic Acids with Superior Hybridization Properties and Water Solubility

    Bichismita Sahu;Iulia Sacui;Srinivas Rapireddy;Kimberly J. Zanotti

  • Experimental and computational investigation of unsymmetrical cyanine dyes: understanding torsionally responsive fluorogenic dyes.

    Gloria L. Silva;Volkan Ediz;and David Yaron;Bruce A. Armitage

  • Polymerization of Preformed Self-Organized Assemblies

    David F. O'Brien;Bruce Armitage;Alto Benedicto;Doyle E. Bennett

  • Cationic Anthraquinone Derivatives as Catalytic DNA Photonucleases: Mechanisms for DNA Damage and Quinone Recycling

    Bruce Armitage;Changjun Yu;Chelladurai Devadoss;Gary B. Schuster

  • Fluorescent DNA nanotags: supramolecular fluorescent labels based on intercalating dye arrays assembled on nanostructured DNA templates.

    Andrea L. Benvin;Yehuda Creeger;Gregory W. Fisher;Byron Ballou

  • Improved photostability and fluorescence properties through polyfluorination of a cyanine dye.

    Babu Rao Renikuntla;Heather C. Rose;Joby Eldo;Alan S. Waggoner

  • Electron-Transfer Reactions in the Marcus Inverted Region. Charge Recombination versus Charge Shift Reactions

    Ian R. Gould;Jacques E. Moser;Bruce Armitage;Samir Farid

  • Molecular Recognition of PNA-Containing Hybrids: Spontaneous Assembly of Helical Cyanine Dye Aggregates on PNA Templates

    Jeffrey O. Smith;Darren A. Olson;Bruce A. Armitage

  • Synthesis of new fluorogenic cyanine dyes and incorporation into RNA fluoromodules.

    Tudor P. Constantin;Gloria L. Silva;Kelly L. Robertson;Tamara P. Hamilton

  • Strand invasion of mixed-sequence B-DNA by acridine-linked, gamma-peptide nucleic acid (gamma-PNA).

    Srinivas Rapireddy;Gaofei He;Subhadeep Roy;Bruce A. Armitage

  • Helical Aggregation of Cyanine Dyes on DNA Templates: Effect of Dye Structure on Formation of Homo- and Heteroaggregates

    Rachel A. Garoff;Elizabeth A. Litzinger;Rebecca E. Connor;Irene Fishman

  • Fluorescent DNA Nanotags Based on a Self-Assembled DNA Tetrahedron

    Hayriye Ozhalici-Unal;Bruce A Armitage

  • Enhanced photostability of genetically encodable fluoromodules based on fluorogenic cyanine dyes and a promiscuous protein partner.

    Nathaniel I. Shank;Kimberly J. Zanotti;Frederick Lanni;Peter B. Berget

  • A rainbow of fluoromodules: a promiscuous scFv protein binds to and activates a diverse set of fluorogenic cyanine dyes.

    Hayriye Özhalici-Ünal;Crystal Lee Pow;Sarah A. Marks;Lawrence D. Jesper

  • Imaging of RNA in live cells.

    Bruce A Armitage

  • Hybridization of PNA to structured DNA targets: quadruplex invasion and the overhang effect.

    Bhaskar Datta;Bruce A Armitage

  • Formation of a PNA2-DNA2 hybrid quadruplex.

    Bhaskar Datta;Christoph Schmitt;Bruce A. Armitage

Frequent Co-Authors

David F. O'Brien
David F. O'Brien University of Arizona
Alan S. Waggoner
Alan S. Waggoner Carnegie Mellon University
Marcel P. Bruchez
Marcel P. Bruchez Carnegie Mellon University
Patricia L. Opresko
Patricia L. Opresko University of Pittsburgh
W. David Wilson
W. David Wilson Georgia State University
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Seth R. Marder
Seth R. Marder University of Colorado Boulder
Samir Farid
Samir Farid University of Rochester
Jacques-E. Moser
Jacques-E. Moser École Polytechnique Fédérale de Lausanne
Krzysztof Matyjaszewski
Krzysztof Matyjaszewski Carnegie Mellon University

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