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Mario Zoratti

Mario Zoratti

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
16904
World Ranking
7777
National Ranking
197

Overview

Mario Zoratti is affiliated with the University of Padua in Italy and has contributed extensively to biochemistry, genetics, and molecular biology as well as medicine through their research efforts.

The scientist's work spans several main topics, including:

  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Neuroscience and Neuropharmacology Research
  • Ion channel regulation and function
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • Calcium signaling and nucleotide metabolism

Zoratti has published in various subfields of study such as molecular biology, cellular and molecular neuroscience, epidemiology, physiology, and biomaterials.

The scientist's frequent co-authors include:

  • Ildikò Szabó
  • Lucia Biasutto
  • Andrea Mattarei
  • Sofia Parrasia
  • Andrea Rossa

Mario Zoratti has contributed publications to several notable venues, frequently appearing in:

  • Redox Biology
  • Molecular Pharmaceutics
  • Journal of Experimental & Clinical Cancer Research
  • Cell Death and Disease
  • Nature Communications

Selected papers authored or co-authored by Zoratti include:

  • "Targeting mitochondrial ion channels for cancer therapy," 2020, Redox Biology
  • "Peptides as Pharmacological Carriers to the Brain: Promises, Shortcomings and Challenges," 2022, Molecular Pharmaceutics
  • "Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family," 2020, Redox Biology
  • "Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model," 2022, Journal of Experimental & Clinical Cancer Research
  • "Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo," 2022, Cell Death and Disease

Best Publications

  • The mitochondrial permeability transition.

    Mario Zoratti;Ildikò Szabò

  • Dimers of mitochondrial ATP synthase form the permeability transition pore

    Valentina Giorgio;Sophia von Stockum;Manuela Antoniel;Astrid Fabbro

  • Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations.

    Paolo Bernardi;Stefano Vassanelli;Paolo Veronese;Raffaele Colonna

  • The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A.

    I Szabó;M Zoratti

  • Polyphenols and Human Health: A Prospectus

    Francesco Visioli;Catalina Alarcón De La Lastra;Cristina Andres-Lacueva;Michael Aviram

  • Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity

    Ildikò Szabò;Sandra Brutsche;Francesco Tombola;Monica Moschioni

  • Mitochondrial Channels: Ion Fluxes and More

    Ildiko Szabo;Mario Zoratti

  • The mitochondrial megachannel is the permeability transition pore.

    Ildikó Szabó;Mario Zoratti

  • Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes.

    Ildikò Szabó;Jürgen Bock;Heike Grassmé;Matthias Soddemann

  • Modulation of the mitochondrial megachannel by divalent cations and protons.

    Ildiko' Szabo';Paolo Bernardi;M. Zoratti

  • A Novel Potassium Channel in Lymphocyte Mitochondria

    Ildikò Szabò;Jurgen Bock;Andreas Jekle;Matthias Soddemann

  • Mitochondrial permeability transitions: how many doors to the house?

    Mario Zoratti;Ildikò Szabò;Umberto De Marchi

  • Tyrosine Kinase-Dependent Activation of a Chloride Channel in CD95-Induced Apoptosis in T Lymphocytes

    Ildikò Szabò;Albrecht Lepple-Wienhues;Kristen N. Kaba;Mario Zoratti

  • The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria

    Valeria Petronilli;Ildiko Szabò;Mario Zoratti

  • The mitochondrial permeability transition pore may comprise VDAC molecules: I. Binary structure and voltage dependence of the pore

    Ildikó Szabó;Mario Zoratti

  • Gadolinium ion inhibits loss of metabolites induced by osmotic shock and large stretch-activated channels in bacteria.

    Catherine Berrier;Alain Coulombe;Ildiko Szabo;Mario Zoratti

  • The mitochondrial permeability transition pore may comprise VDAC molecules. II. The electrophysiological properties of VDAC are compatible with those of the mitochondrial megachannel

    Ildikó Szabó;Vito De Pinto;Mario Zoratti

  • Electrophysiology of the inner mitochondrial membrane.

    Mario Zoratti;Ildikó Szabó

  • Helicobacter pylori Vacuolating Toxin Forms Anion-Selective Channels in Planar Lipid Bilayers: Possible Implications for the Mechanism of Cellular Vacuolation

    Francesco Tombola;Cristina Carlesso;Ildikò Szabò;Marina de Bernard

  • Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells

    Luigi Leanza;Brian Henry;Nicola Sassi;Mario Zoratti

Frequent Co-Authors

Ildikò Szabò
Ildikò Szabò University of Padua
Erich Gulbins
Erich Gulbins University of Duisburg-Essen
Valeria Petronilli
Valeria Petronilli University of Padua
Emanuele Papini
Emanuele Papini University of Padua
Spiridione Garbisa
Spiridione Garbisa University of Padua
Cesare Montecucco
Cesare Montecucco University of Padua
Paolo Bernardi
Paolo Bernardi University of Padua
Livio Trentin
Livio Trentin University of Padua
Giuseppe Del Giudice
Giuseppe Del Giudice GlaxoSmithKline (United Kingdom)
Rino Rappuoli
Rino Rappuoli Imperial College London

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