Alan C. Sartorelli

Research.com Recognitions

• 1990 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood- cerebrospinal-fluid drug-permeability barrier

  Vallabhaneni V. Rao;Julie L. Dahlheimer;Mark E. Bardgett;Abraham Z. Snyder

  771
  Citations

• Classification of Antineoplastic Agents by their Selective Toxicities toward Oxygenated and Hypoxic Tumor Cells

  Beverly A. Teicher;John S. Lazo;Alan C. Sartorelli

  719
  Citations

• The Leukotriene C4 Transporter MRP1 Regulates CCL19 (MIP-3β, ELC)–Dependent Mobilization of Dendritic Cells to Lymph Nodes

  Davide F Robbiani;Rick A Finch;Dirk Jäger;William A Muller

  586
  Citations

• Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity

  Rick Avery Finch;Mao Chin Liu;Susan P. Grill;William C. Rose

  453
  Citations

• The hypoxic tumor cell: a target for selective cancer chemotherapy.

  Katherine A. Kennedy;Beverly A. Teicher;Sara Rockwell;Alan C. Sartorelli

  416
  Citations

• Differentiation of immortal cells inhibits telomerase activity.

  Harsh W. Sharma;John A. Sokoloski;Jose R. Perez;Jean Yves Maltese

  400
  Citations

• Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins.

  Germana Rappa;Aurelio Lorico;Richard A. Flavell;Alan C. Sartorelli

  375
  Citations

• Therapeutic attack of hypoxic cells of solid tumors: presidential address

  Alan C. Sartorelli

  362
  Citations

• Preferential Activation of Mitomycin C to Cytotoxic Metabolites by Hypoxic Tumor Cells

  Katherine A. Kennedy;Sara Rockwell;Alan C. Sartorelli

  319
  Citations

• Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione.

  Aurelio Lorico;Germana Rappa;Rick A. Finch;Di Yang

  314
  Citations

• Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity.

  Rick A. Finch;Mao Chin Liu;Ann H. Cory;Joseph G. Cory

  293
  Citations

• Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer.

  Joseph B. Weissberg;Yung H. Son;Rose J. Papac;Clarence Sasaki

  288
  Citations

• Potential bioreductive alkylating agents. 1. Benzoquinone derivatives.

  Ai Jeng Lin;Lucille A. Cosby;Charles W. Shansky;Alan C. Sartorelli

  281
  Citations

• Antineoplastic and immunosuppressive agents

  Alan C. Sartorelli;David G. Johns

  251
  Citations

• Role of NADPH:Cytochrome c Reductase and DT-Diaphorase in the Biotransformation of Mitomycin C

  Susan R. Keyes;Paula M. Fracasso;David C. Heimbrook;Sara Rockwell

  247
  Citations

• Enhancement by hyperthermia of the in vitro cytotoxicity of mitomycin C toward hypoxic tumor cells

  Beverly A. Teicher;Charles D. Kowal;Katherine A. Kennedy;Alan C. Sartorelli

  226
  Citations

• Molecular Actions and Targets for Cancer Chemotherapeutic Agents

  Alan C. Sartorelli;John S. Lazo;Joseph R. Bertino

  223
  Citations

• Synthesis and antitumor activity of amino derivatives of pyridine-2-carboxaldehyde thiosemicarbazone

  Mao Chin Liu;Tai Chun Lin;Alan C. Sartorelli

  223
  Citations

• STUDIES ON THE INHIBITION OF DIHYDROFOLATE REDUCTASE BY THE FOLATE ANTAGONISTS.

  Joseph R. Bertino;Barbara A. Booth;Allan L. Bieber;Arlene Cashmore

  221
  Citations

• Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis.

  Jana S. Eaton;Z. Ping Lin;Alan C. Sartorelli;Nicholas D. Bonawitz

  208
  Citations