Robert E. Handschumacher

Research.com Recognitions

• 1982 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A

  Robert E. Handschumacher;Matthew W. Harding;Jeffrey Rice;Rhett J. Drugge

  2364
  Citations

• Isolation and amino acid sequence of cyclophilin

  M W Harding;R E Handschumacher;D W Speicher

  384
  Citations

• Cyclophilin: distribution and variant properties in normal and neoplastic tissues.

  A J Koletsky;M W Harding;R E Handschumacher

  286
  Citations

• Orotidylic Acid Decarboxylase: Inhibition Studies with Azauridine 5'-Phosphate

  R.E. Handschumacher

  253
  Citations

• The Cyclosporin A-binding Immunophilin CyP-40 and the FK506-binding Immunophilin hsp56 Bind to a Common Site on hsp90 and Exist in Independent Cytosolic Heterocomplexes with the Untransformed Glucocorticoid Receptor

  Janet K. Owens-Grillo;Kai Hoffmann;Kevin A. Hutchison;Anthony W. Yem

  246
  Citations

• A rapid quantitative determination of deoxyribonucleoside triphosphates based on the enzymatic synthesis of DNA.

  Alan W. Solter;R.E. Handschumacher

  212
  Citations

• The biochemical activity of 6-azauridine: interference with pyrimidine metabolism in transplantable mouse tumors.

  C.A. Pasternak;R.E. Handschumacher

  185
  Citations

• Novel Single-Pass Exchange of Circulating Uridine in Rat Liver

  Thomas Gasser;James D. Moyer;Robert E. Handschumacher

  172
  Citations

• Partial Purification of Human Lymphocyte-Activating Factor (LAF) by Ultrafiltration and Electrophoretic Techniques

  Lawrence B. Lachman;Miles P. Hacker;Robert E. Handschumacher

  167
  Citations

• Cyclophilin-40, a protein with homology to the P59 component of the steroid receptor complex. Cloning of the cDNA and further characterization.

  L. J. Kieffer;T. W. Seng;Wei Li;D. G. Osterman

  166
  Citations

• Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update.

  Giuseppe Pizzorno;Deliang Cao;Janine J Leffert;Rosalind L Russell

  162
  Citations

• Potentiation of the T lymphocyte response to mitogens. III. Properties of the mediator(s) from adherent cells.

  Igal Gery;Robert E. Handschumacher

  162
  Citations

• Preparation of lymphocyte-activating factor from continuous murine macrophage cell lines☆

  Lawrence B. Lachman;Miles P. Hacker;Gershwin T. Blyden;Robert E. Handschumacher

  162
  Citations

• Salvage of Circulating Pyrimidine Nucleosides in the Rat

  James D. Moyer;James T. Oliver;Robert E. Handschumacher

  152
  Citations

• Isolation and characterization of a 40-kDa cyclophilin-related protein.

  L J Kieffer;T Thalhammer;R E Handschumacher

  152
  Citations

• Clinical, Biological, and Biochemical Effects of Pyrazofurin

  Edwin C. Cadman;Douglas E. Dix;Robert E. Handschumacher

  149
  Citations

• Cyclosporin A potentiates the dexamethasone-induced mouse mammary tumor virus-chloramphenicol acetyltransferase activity in LMCAT cells: a possible role for different heat shock protein-binding immunophilins in glucocorticosteroid receptor-mediated gene expression

  J.-M. Renoir;C. Mercier-Bodard;K. Hoffmann;S. Le Bihan

  137
  Citations

• Fatty livers induced by orotic acid. II. Changes in nucleotide metabolism.

  Leo H. von Euler;Robert J. Rubin;R. E. Handschumacher

  131
  Citations

• Cyclophilin, a primary molecular target for cyclosporine. Structural and functional implications.

  Matthew W. Harding;Robert E. Handschumacher

  117
  Citations

• Fatty livers induced by orotic acid. I. Accumulation and metabolism of lipids.

  W.A. Creasey;L. Hankin;R.E. Handschumacher

  114
  Citations