John S. Lazo

Research.com Recognitions

• 1997 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Overexpression of metallothionein confers resistance to anticancer drugs.

  Susan L. Kelley;Alakananda Basu;Beverly A. Teicher;Miles P. Hacker

  850
  Citations

• Classification of Antineoplastic Agents by their Selective Toxicities toward Oxygenated and Hypoxic Tumor Cells

  Beverly A. Teicher;John S. Lazo;Alan C. Sartorelli

  719
  Citations

• Chemical genetics of Plasmodium falciparum.

  W. Armand Guiguemde;Anang A. Shelat;David Bouck;Sandra Duffy

  667
  Citations

• Low molecular weight inhibitors of Myc-Max interaction and function.

  Xiaoying Yin;Christine Giap;John S Lazo;Edward V Prochownik;Edward V Prochownik

  477
  Citations

• microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells

  Peng Wang;Fangdong Zou;Xiaodong Zhang;Hua Li

  375
  Citations

• Enhanced Sensitivity to Oxidative Stress in Cultured Embryonic Cells from Transgenic Mice Deficient in Metallothionein I and II Genes

  J. S. Lazo;Y. Kondo;D. Dellapiazza;A. E. Michalska

  357
  Citations

• The Liver X Receptor Ligand T0901317 Decreases Amyloid β Production in Vitro and in a Mouse Model of Alzheimer's Disease

  Radosveta P. Koldamova;Iliya M. Lefterov;Matthias Staufenbiel;Darren Wolfe

  326
  Citations

• Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide

  MA Schwarz;JS Lazo;JC Yalowich;WP Allen

  317
  Citations

• Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages

  Gabriela Molina;Andreas Vogt;Ahmet Bakan;Weixiang Dai

  295
  Citations

• 22R-Hydroxycholesterol and 9-cis-Retinoic Acid Induce ATP-binding Cassette Transporter A1 Expression and Cholesterol Efflux in Brain Cells and Decrease Amyloid β Secretion

  Radosveta P. Koldamova;Iliya M. Lefterov;Milos D. Ikonomovic;John Skoko

  294
  Citations

• Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-beta precede bleomycin-induced pulmonary fibrosis in mice.

  D G Hoyt;J S Lazo

  280
  Citations

• Diallyl trisulfide-induced G2–M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc25C

  Dong Xiao;Anna Herman-Antosiewicz;Jedrzej Antosiewicz;Hui Xiao

  256
  Citations

• Enhanced Apoptosis in Metallothionein Null Cells

  Yukihiro Kondo;James M. Rusnak;Dale G. Hoyt;Catherine E. Settineri

  231
  Citations

• Identification of a Potent and Selective Pharmacophore for Cdc25 Dual Specificity Phosphatase Inhibitors.

  John S. Lazo;Kaoru Nemoto;Katharine E. Pestell;Kathleen Cooley

  229
  Citations

• The Benzo[c]phenanthridine Alkaloid, Sanguinarine, Is a Selective, Cell-active Inhibitor of Mitogen-activated Protein Kinase Phosphatase-1

  Andreas Vogt;Aletheia Tamewitz;John Skoko;Rachel P. Sikorski

  223
  Citations

• Role of metallothionein in carcinogenesis.

  M G Cherian;S B Howell;N Imura;C D Klaassen

  206
  Citations

• Cytoplasmic metallothionein overexpression protects NIH 3T3 cells from tert-butyl hydroperoxide toxicity.

  Margaret A. Schwarz;John S. Lazo;Jack C. Yalowich;Ian Reynolds

  202
  Citations

• Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z.

  Sager J. Gosai;Joon Hyeok Kwak;Cliff J. Luke;Olivia S. Long

  199
  Citations

• Cationic liposomes for direct gene transfer in therapy of cancer and other diseases.

  Hassan Farhood;Xiang Gao;Kyonghee Son;John S. Lazo

  180
  Citations

• 22R-Hydroxycholesterol and 9-cis-Retinoic Acid Induce ATP-binding Cassette Transporter A1 Expression and Cholesterol Efflux in Brain Cells and Decrease Amyloid Secretion*

  Radosveta P. Koldamova;Iliya M. Lefterov;Milos D. Ikonomovic;John Skoko

  10
  Citations