What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Biochemistry, Molecular biology, Metallothionein, In vitro and Cancer research.
John S. Lazo combines subjects such as Bleomycin hydrolase and In vivo with his study of Biochemistry.
His work deals with themes such as Cell culture, Cell growth, Chelerythrine, Protein kinase A and Sanguinarine, which intersect with Molecular biology.
His research in Metallothionein intersects with topics in Lipid peroxidation, Antioxidant, Transfection, Intracellular and Drug resistance.
The concepts of his In vitro study are interwoven with issues in Pharmacokinetics and Metabolism.
John S. Lazo has researched Cancer research in several fields, including Cancer, Cell cycle, Cell cycle checkpoint, Diallyl trisulfide and Melphalan.
His most cited work include:
- Overexpression of metallothionein confers resistance to anticancer drugs. (544 citations)
- Classification of Antineoplastic Agents by their Selective Toxicities toward Oxygenated and Hypoxic Tumor Cells (513 citations)
- Chemical genetics of Plasmodium falciparum. (442 citations)
What are the main themes of his work throughout his whole career to date?
John S. Lazo focuses on Biochemistry, Molecular biology, Cell biology, In vitro and Phosphatase.
Biochemistry is represented through his Enzyme, Kinase, Dual-specificity phosphatase, Protein tyrosine phosphatase and Cdc25 research.
His Molecular biology research includes elements of Cell culture, Transfection, Bleomycin hydrolase, Bleomycin and Metallothionein.
John S. Lazo interconnects Apoptosis and Cell in the investigation of issues within Cell biology.
His study looks at the intersection of In vitro and topics like In vivo with Cancer research.
His Phosphatase study incorporates themes from CDC25A, Small molecule, Enzyme inhibitor and Protein kinase A.
He most often published in these fields:
- Biochemistry (33.56%)
- Molecular biology (24.32%)
- Cell biology (13.01%)
What were the highlights of his more recent work (between 2009-2018)?
- Biochemistry (33.56%)
- Drug discovery (5.82%)
- Computational biology (4.11%)
In recent papers he was focusing on the following fields of study:
Biochemistry, Drug discovery, Computational biology, Small molecule and Cancer are his primary areas of study.
His research ties Pharmacokinetics and Biochemistry together.
The various areas that he examines in his Drug discovery study include Carcinogenesis, RNA interference, Immunology and Drug.
His Drug research focuses on Cancer drug discovery and how it connects with Molecular biology.
His Cancer research incorporates elements of Protein kinase C, Kinase, MAPK/ERK pathway and Pharmacology.
His Kinase research is multidisciplinary, relying on both Cancer research, G protein-coupled receptor and Motility.
Between 2009 and 2018, his most popular works were:
- Chemical genetics of Plasmodium falciparum. (442 citations)
- Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z. (141 citations)
- Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments. (83 citations)
In his most recent research, the most cited papers focused on:
John S. Lazo mainly investigates Biochemistry, Drug discovery, Computational biology, Small molecule and Bioinformatics.
His biological study spans a wide range of topics, including Antiparasitic and In vivo.
Neglected Disease and Drug resistance is closely connected to Immunology in his research, which is encompassed under the umbrella topic of Drug discovery.
His studies in Computational biology integrate themes in fields like Parasitology, Chemical genetics, Drug development, Malaria and Cell based assays.
His research integrates issues of Rottlerin, Cancer stem cell, Stem cell, Carcinoma and Pharmacology in his study of Small molecule.
His Transfection research integrates issues from Cancer cell and Cancer.
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