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Biology and Biochemistry

D-Index
47
Citations
10152
World Ranking
18623
National Ranking
7616

Overview

Toshio Tsukiyama is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research predominantly lies within the field of Biochemistry, Genetics and Molecular Biology, with a focused expertise in Molecular Biology. Additional subfields of study include Plant Science, Cancer Research, Genetics, and Biophysics.

The scientist's work covers a range of topics, notably:

  • Genomics and Chromatin Dynamics
  • Fungal and yeast genetics research
  • Epigenetics and DNA Methylation
  • RNA and protein synthesis mechanisms
  • Chromosomal and Genetic Variations
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer

Toshio Tsukiyama has contributed to multiple publications across several notable venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • BIO-PROTOCOL
  • Annual Review of Genetics
  • Molecular Biology and Evolution

Some recent research papers authored include:

  • "H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress" (2020) published in Nature Communications
  • "Novel Classes and Evolutionary Turnover of Histone H2B Variants in the Mammalian Germline" (2022) published in Molecular Biology and Evolution
  • "Quiescence in Saccharomyces cerevisiae" (2022) published in Annual Review of Genetics
  • "RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry" (2021) published in eLife
  • "Inhibition of transcription leads to rewiring of locus-specific chromatin proteomes" (2020) published in Genome Research

The scientist has collaborated frequently with several colleagues, including Christine E. Cucinotta, Rachel Dell, Kris G. Alavattam, Anca B. Mihalas, and Sonali Arora.

Best Publications

  • ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

    Toshio Tsukiyama;Peter B. Becker;Peter B. Becker;Carl Wu

  • Purification and properties of an ATP-dependent nucleosome remodeling factor.

    Toshio Tsukiyama;Carl Wu

  • Chromatin remodelling at promoters suppresses antisense transcription

    Iestyn Whitehouse;Oliver J. Rando;Jeff Delrow;Toshio Tsukiyama

  • ISWI, a member of the SWl2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor

    Toshio Tsukiyama;Carla Daniel;John Tamkun;Carl Wu

  • CHARACTERIZATION OF THE IMITATION SWITCH SUBFAMILY OF ATP-DEPENDENT CHROMATIN-REMODELING FACTORS IN SACCHAROMYCES CEREVISIAE

    Toshio Tsukiyama;Jeffrey Palmer;Carolyn C. Landel;Joseph Shiloach

  • The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo.

    Renate Deuring;Laura Fanti;Laura Fanti;Jennifer A Armstrong;Melinda Sarte

  • The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p.

    Jesse P Goldmark;Thomas G Fazzio;Thomas G Fazzio;Pete W Estep;George M Church

  • Chromatin remodeling and transcription.

    Toshio Tsukiyama;Carl Wu

  • Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression.

    Thomas G. Fazzio;Charles Kooperberg;Jesse P. Goldmark;Cassandra Neal

  • Dynamic changes in histone acetylation regulate origins of DNA replication

    Ashwin Unnikrishnan;Philip R Gafken;Toshio Tsukiyama

  • Drosophila NURF-55, a WD repeat protein involved in histone metabolism.

    Marian A. Martínez-Balbás;Toshio Tsukiyama;David Gdula;Carl Wu

  • Interactions of Isw2 Chromatin Remodeling Complex with Nucleosomal Arrays: Analyses Using Recombinant Yeast Histones and Immobilized Templates

    Marnie E. Gelbart;Thomas Rechsteiner;Timothy J. Richmond;Toshio Tsukiyama

  • The in vivo functions of ATP-dependent chromatin-remodelling factors

    Toshio Tsukiyama

  • Improved background correction for spotted DNA microarrays.

    Charles L. Kooperberg;Thomas G. Fazzio;Jeffrey J. Delrow;Toshio Tsukiyama

  • ATP-dependent chromatin remodeling shapes the DNA replication landscape

    Jack A Vincent;Tracey J Kwong;Toshio Tsukiyama

  • Role of Nucleosome Remodeling Factor NURF in Transcriptional Activation of Chromatin

    Gaku Mizuguchi;Toshio Tsukiyama;Jan Wisniewski;Carl Wu

  • Yeast Isw1p forms two separable complexes in vivo.

    Jay C. Vary;Vamsi K. Gangaraju;Jun Qin;Jun Qin;Carolyn Church Landel

  • Role of histone tails in nucleosome remodeling by Drosophila NURF

    Philippe T. Georgel;Toshio Tsukiyama;Carl Wu

  • Functional difference between Ad4BP and ELP, and their distributions in steroidogenic tissues.

    K Morohashi;H Iida;M Nomura;O Hatano

  • Chromatin Remodeling In Vivo: Evidence for a Nucleosome Sliding Mechanism

    Thomas G Fazzio;Toshio Tsukiyama

Frequent Co-Authors

Carl Wu
Carl Wu Johns Hopkins University
Jeffrey J. Delrow
Jeffrey J. Delrow Fred Hutchinson Cancer Research Center
Tamar Schlick
Tamar Schlick New York University
Charles Kooperberg
Charles Kooperberg Fred Hutchinson Cancer Research Center
William Stafford Noble
William Stafford Noble University of Washington
Jun Qin
Jun Qin Cleveland Clinic Lerner College of Medicine
Peter B. Becker
Peter B. Becker Ludwig-Maximilians-Universität München
Sue Biggins
Sue Biggins Fred Hutchinson Cancer Research Center
Oliver J. Rando
Oliver J. Rando University of Massachusetts Chan Medical School
Jef D. Boeke
Jef D. Boeke New York University

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