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D-Index & Metrics

Genetics

D-Index
45
Citations
10326
World Ranking
4211
National Ranking
1815

Research.com Recognitions

  • 2018 - Fellow of the American Academy of Arts and Sciences
  • 2015 - Member of the National Academy of Sciences

Overview

Sue Biggins is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research portfolio encompasses multiple areas within biochemistry, genetics, and molecular biology, with a significant focus on molecular biology and cell biology. Their work also touches on agricultural and biological sciences, particularly plant science, and genetics.

The scientist's research topics include:

  • Microtubule and mitosis dynamics
  • Genomics and chromatin dynamics
  • Chromosomal and genetic variations
  • Photosynthetic processes and mechanisms
  • Fungal and yeast genetics research
  • RNA and protein synthesis mechanisms
  • Plant nutrient uptake and metabolism

Recent papers authored or co-authored by Sue Biggins are:

  • Computed structures of core eukaryotic protein complexes, 2021, Science
  • H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress, 2020, Nature Communications
  • chTOG is a conserved mitotic error correction factor, 2020, eLife
  • Kinetochore-bound Mps1 regulates kinetochore-microtubule attachments via Ndc80 phosphorylation, 2021, The Journal of Cell Biology
  • Tension can directly suppress Aurora B kinase-triggered release of kinetochore-microtubule attachments, 2022, Nature Communications

The frequent coauthors working alongside Sue Biggins include:

  • Charles L. Asbury
  • Andrew R. Popchock
  • Christian R. Nelson
  • Joshua D. Larson
  • Sabrine Hédouin

Their research is regularly published in several scientific venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Nature Communications
  • The Journal of Cell Biology
  • Current Biology

Their contributions have been recognized with memberships and fellowships, including:

  • Fellow of the American Academy of Arts and Sciences, 2018
  • Member of the National Academy of Sciences, 2015

Best Publications

  • Tension directly stabilizes reconstituted kinetochore-microtubule attachments

    Bungo Akiyoshi;Krishna K. Sarangapani;Andrew F. Powers;Christian R. Nelson

  • Histone variants: deviants?

    Rohinton T. Kamakaka;Sue Biggins

  • The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint

    Sue Biggins;Andrew W. Murray

  • The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast

    Sue Biggins;Fedor F. Severin;Needhi Bhalla;Ingrid Sassoon

  • Computed structures of core eukaryotic protein complexes.

    Ian R. Humphreys;Jimin Pei;Minkyung Baek;Aditya Krishnakumar

  • Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores.

    Nitobe London;Steven Ceto;Jeffrey A. Ranish;Sue Biggins

  • The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores.

    Benjamin A. Pinsky;Charles Kung;Kevan M. Shokat;Kevan M. Shokat;Sue Biggins

  • The spindle checkpoint: tension versus attachment.

    Benjamin A. Pinsky;Sue Biggins

  • The NoCut Pathway Links Completion of Cytokinesis to Spindle Midzone Function to Prevent Chromosome Breakage

    Caren Norden;Manuel Mendoza;Jeroen Dobbelaere;Chitra V. Kotwaliwale

  • Signalling dynamics in the spindle checkpoint response

    Nitobe London;Sue Biggins

  • Centromere identity is specified by a single centromeric nucleosome in budding yeast

    Suzanne Furuyama;Sue Biggins

  • Proteolysis Contributes to the Exclusive Centromere Localization of the Yeast Cse4/CENP-A Histone H3 Variant

    Kimberly A. Collins;Suzanne Furuyama;Sue Biggins

  • Mutation of YCS4, a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior.

    Needhi Bhalla;Sue Biggins;Andrew W. Murray;Andrew W. Murray

  • The composition, functions, and regulation of the budding yeast kinetochore.

    Sue Biggins

  • Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint

    Nitobe London;Sue Biggins

  • Yeast ubiquitin-like genes are involved in duplication of the microtubule organizing center.

    S Biggins;I Ivanovska;M D Rose

  • An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain.

    Prerana Ranjitkar;Maximilian O. Press;Xianhua Yi;Richard Baker

  • A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments

    Matthew P. Miller;Charles L. Asbury;Sue Biggins

  • The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly.

    Stéphanie Buvelot;Sean Y. Tatsutani;Danielle Vermaak;Sue Biggins

  • Genes Involved in Sister Chromatid Separation and Segregation in the Budding Yeast Saccharomyces cerevisiae

    Sue Biggins;Needhi Bhalla;Amy Chang;Dana L. Smith

Frequent Co-Authors

Andrew W. Murray
Andrew W. Murray Harvard University
Benjamin A. Pinsky
Benjamin A. Pinsky Stanford University
Jeffrey A. Ranish
Jeffrey A. Ranish University of Washington
Mark D. Rose
Mark D. Rose Princeton University
Trisha N. Davis
Trisha N. Davis University of Washington
Tamir Gonen
Tamir Gonen University of California, Los Angeles
Edward D. Salmon
Edward D. Salmon University of North Carolina at Chapel Hill
Chad A. Brautigam
Chad A. Brautigam The University of Texas Southwestern Medical Center
Scott Keeney
Scott Keeney Memorial Sloan Kettering Cancer Center
Michael J. MacCoss
Michael J. MacCoss University of Washington

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