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Biology and Biochemistry

D-Index
54
Citations
18282
World Ranking
15369
National Ranking
6416

Overview

Jeffrey A. Ranish is affiliated with the University of Washington in the United States and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, as well as Chemistry. Their research spans multiple subfields, including Molecular Biology, Spectroscopy, Physiology, Computational Mechanics, and Pathology and Forensic Medicine.

Their work focuses on a range of scientific topics such as:

  • Genomics and Chromatin Dynamics
  • Advanced Proteomics Techniques and Applications
  • Mass Spectrometry Techniques and Applications
  • Chromatin Remodeling and Cancer
  • RNA Research and Splicing
  • CRISPR and Genetic Engineering
  • Ion-surface interactions and analysis

Ranish has published research in multiple journals, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • eLife
  • Cell
  • Molecular Cell

Notable recent papers include:

  • A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms, 2020, Cell
  • Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis, 2020, Molecular Cell
  • Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism, 2020, Proceedings of the National Academy of Sciences
  • PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing, 2022, Nature Metabolism
  • Chromatin-Associated Protein Complexes Link DNA Base J and Transcription Termination in Leishmania, 2021, mSphere

Frequent co-authors collaborating with Ranish include:

  • Jie Luo
  • Marjorie Brand
  • Mark A. Gillespie
  • Carmen G. Palii
  • Mehar Un Nissa

Best Publications

  • Integrated genomic and proteomic analyses of a systematically perturbed metabolic network.

    Trey Ideker;Vesteinn Thorsson;Jeffrey A. Ranish;Rowan Christmas

  • Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy

    Cigall Kadoch;Diana C Hargreaves;Courtney Hodges;Laura Elias

  • An Essential Switch in Subunit Composition of a Chromatin Remodeling Complex during Neural Development

    Julie Lessard;Jiang I. Wu;Jeffrey A. Ranish;Mimi Wan

  • Computational prediction of proteotypic peptides for quantitative proteomics

    Parag Mallick;Markus Schirle;Sharon S Chen;Mark R Flory

  • An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.

    Lena Ho;Jehnna L. Ronan;Jiang Wu;Brett T. Staahl

  • CTCF physically links cohesin to chromatin

    Eric D. Rubio;David J. Reiss;Piri L. Welcsh;Christine M. Disteche

  • Tension directly stabilizes reconstituted kinetochore-microtubule attachments

    Bungo Akiyoshi;Krishna K. Sarangapani;Andrew F. Powers;Christian R. Nelson

  • Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes

    Nazar Mashtalir;Nazar Mashtalir;Andrew R. D’Avino;Andrew R. D’Avino;Brittany C. Michel;Brittany C. Michel;Jie Luo

  • Quantitative proteome analysis by solid-phase isotope tagging and mass spectrometry.

    Huilin Zhou;Jeffrey A. Ranish;Julian D. Watts;Ruedi Aebersold

  • A transcription reinitiation intermediate that is stabilized by activator.

    Natalya Yudkovsky;Jeffrey A. Ranish;Jeffrey A. Ranish;Steven Hahn;Steven Hahn

  • Automated statistical analysis of protein abundance ratios from data generated by stable-isotope dilution and tandem mass spectrometry.

    Xiao Jun Li;Hui Zhang;Jeffrey A. Ranish;Ruedi Aebersold

  • The study of macromolecular complexes by quantitative proteomics.

    Jeffrey A. Ranish;Eugene C. Yi;Deena M. Leslie;Samuel O. Purvine

  • Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores.

    Nitobe London;Steven Ceto;Jeffrey A. Ranish;Sue Biggins

  • A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A

    Giuseppina Giglia-Mari;Frederic Coin;Jeffrey A Ranish;Deborah Hoogstraten

  • Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry

    Frank Desiere;Eric W Deutsch;Alexey I Nesvizhskii;Parag Mallick

  • Yeast nuclear extract contains two major forms of RNA polymerase II mediator complexes.

    Ying Liu;Jeffrey A. Ranish;Ruedi Aebersold;Steven Hahn

  • Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB.

    Jeffrey A. Ranish;Natalya Yudkovsky;Steven Hahn

  • Phosphorylation of the Transcription Elongation Factor Spt5 by Yeast Bur1 Kinase Stimulates Recruitment of the PAF Complex

    Ying Liu;Linda Warfield;Chao Zhang;Jie Luo

  • Calcineurin/NFAT Signaling Is Required for Neuregulin-Regulated Schwann Cell Differentiation

    Shih Chu Kao;Hai Wu;Hai Wu;Jianming Xie;Ching-Pin Chang;Ching-Pin Chang

  • Dynamic changes in transcription factor complexes during erythroid differentiation revealed by quantitative proteomics.

    Marjorie Brand;Jeffrey A Ranish;Nicolas T Kummer;Joan Hamilton

Frequent Co-Authors

Steven Hahn
Steven Hahn Fred Hutchinson Cancer Research Center
Jimmy K. Eng
Jimmy K. Eng University of Washington
Gerald R. Crabtree
Gerald R. Crabtree Stanford University
Sue Biggins
Sue Biggins Fred Hutchinson Cancer Research Center
Marilyn Parsons
Marilyn Parsons University of Washington
Stephen D. Hauschka
Stephen D. Hauschka University of Washington
Peter J. Myler
Peter J. Myler Seattle Children's Hospital
Mark Groudine
Mark Groudine Fred Hutchinson Cancer Research Center
Leroy Hood
Leroy Hood University of Washington

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