Michael J. MacCoss mostly deals with Proteomics, Computational biology, Biochemistry, Tandem mass spectrometry and Shotgun proteomics. His Proteomics study combines topics from a wide range of disciplines, such as Integral membrane protein, Proteome, Bioinformatics, Vesicle-associated membrane protein 8 and Chromatography. His Computational biology research is multidisciplinary, incorporating perspectives in Genetics, Genome, Human genome, ENCODE and DNase-Seq.
As part of one scientific family, he deals mainly with the area of Biochemistry, narrowing it down to issues related to the Cell biology, and often Mitochondrial Degradation and PINK1. His work on Peptide spectral library as part of general Tandem mass spectrometry study is frequently connected to Data acquisition, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His work in Shotgun proteomics addresses subjects such as Mass spectrum, which are connected to disciplines such as Fourier transform ion cyclotron resonance, Data reduction and Protein mass spectrometry.
His main research concerns Proteomics, Mass spectrometry, Cell biology, Computational biology and Biochemistry. The Proteomics study combines topics in areas such as Proteome, Chromatography and Tandem mass spectrometry. His Mass spectrometry study combines topics in areas such as Biological system and Data-independent acquisition.
While the research belongs to areas of Cell biology, Michael J. MacCoss spends his time largely on the problem of Transcription factor, intersecting his research to questions surrounding Identification and Green fluorescent protein. The study incorporates disciplines such as Molecular biology, Targeted proteomics and Genome, Gene in addition to Computational biology. His is doing research in Ubiquitin and Protein turnover, both of which are found in Biochemistry.
His primary scientific interests are in Cell biology, Proteomics, Computational biology, Proteome and Mass spectrometry. The concepts of his Cell biology study are interwoven with issues in Mutant, Giardia lamblia, Innate immune system, Protein turnover and Potato leafroll virus. His Proteomics research includes elements of Evolutionary biology, Field, Mating system, Diaphorina citri and Data science.
His Computational biology study incorporates themes from De novo sequencing and Sequence database, Genome, Gene. Michael J. MacCoss has researched Proteome in several fields, including Tandem mass spectrometry, Chromatin, Nuclear protein, Bromodomain and Peptide. He combines subjects such as Quantitative proteomics and Data-independent acquisition with his study of Mass spectrometry.
Michael J. MacCoss focuses on Cell biology, Proteomics, Skyline, Data science and Mutation. His Cell biology research is multidisciplinary, relying on both Protein turnover and Biofilm. His research on Proteomics often connects related areas such as Orbitrap.
His study in Skyline is interdisciplinary in nature, drawing from both Data visualization, Data processing, Small molecule and Metabolomics. As a member of one scientific family, Michael J. MacCoss mostly works in the field of Data science, focusing on Field and, on occasion, Group method of data handling. His studies in Mutation integrate themes in fields like Protein aggregation, Microautophagy, Mutant, Glucocerebrosidase and Kinetochore.
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Skyline: an open source document editor for creating and analyzing targeted proteomics experiments
Brendan MacLean;Daniela M. Tomazela;Nicholas Shulman;Matthew Chambers.
Bioinformatics (2010)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins.
PMC (2012)
A cross-platform toolkit for mass spectrometry and proteomics
Matthew C Chambers;Brendan Maclean;Robert Burke;Dario Amodei.
Nature Biotechnology (2012)
Semi-supervised learning for peptide identification from shotgun proteomics datasets
Lukas Käll;Jesse D Canterbury;Jason Weston;William Stafford Noble.
Nature Methods (2007)
Aminoglycoside antibiotics induce bacterial biofilm formation
Lucas R. Hoffman;David A. D'Argenio;Michael J. MacCoss;Zhaoying Zhang.
Nature (2005)
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project
Mark B. Gerstein;Zhi John Lu;Eric L. Van Nostrand;Chao Cheng.
Science (2010)
An expansive human regulatory lexicon encoded in transcription factor footprints
Shane Neph;Jeff Vierstra;Andrew B. Stergachis;Alex P. Reynolds.
Nature (2012)
A METHOD FOR THE COMPREHENSIVE PROTEOMIC ANALYSIS OF MEMBRANE PROTEINS
Christine C. Wu;Michael J. MacCoss;Kathryn E. Howell;John R. Yates.
Nature Biotechnology (2003)
Shotgun identification of protein modifications from protein complexes and lens tissue
Michael J. MacCoss;W. Hayes McDonald;Anita Saraf;Rovshan Sadygov.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Assigning significance to peptides identified by tandem mass spectrometry using decoy databases.
Lukas Käll;John D. Storey;Michael J. MacCoss;William Stafford Noble.
Journal of Proteome Research (2008)
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