Juan Botas

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

  Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  10661
  Citations

• Identification of genes that modify ataxin-1-induced neurodegeneration

  Pedro Fernandez-Funez;Maria Laura Nino-Rosales;Beatrice De Gouyon;Wei Chi She

  778
  Citations

• Huntingtin interacting proteins are genetic modifiers of neurodegeneration.

  Linda S. Kaltenbach;Eliana Romero;Robert R. Becklin;Rakesh Chettier

  514
  Citations

• Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates Neurodegeneration in Spinocerebellar Ataxia Type 1

  Hung Kai Chen;Hung Kai Chen;Pedro Fernandez-Funez;Summer F. Acevedo;Yung C. Lam

  509
  Citations

• Homeotic genes of the bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less

  Gilles Vachon;Barbara Cohen;Christine Pfeifle;M.Elaine McGuffin

  508
  Citations

• The DNA binding specificity of ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein

  Siu-Kwong Chan;Leah Jaffe;Maria Capovilla;Juan Botas

  473
  Citations

• RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS

  Oyinkan A. Sofola;Peng Jin;Yunlong Qin;Ranhui Duan

  379
  Citations

• Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice

  Peter Langfelder;Jeffrey P Cantle;Jeffrey P Cantle;Doxa Chatzopoulou;Nan Wang;Nan Wang

  377
  Citations

• ATAXIN-1 Interacts with the Repressor Capicua in Its Native Complex to Cause SCA1 Neuropathology

  Yung C. Lam;Aaron B. Bowman;Paymaan Jafar-Nejad;Janghoo Lim

  334
  Citations

• Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain

  Dyna I. Shirasaki;Dyna I. Shirasaki;Erin R. Greiner;Erin R. Greiner;Ismael Al-Ramahi;Michelle Gray;Michelle Gray

  320
  Citations

• Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy

  Jerrah K. Holth;Valerie C. Bomben;J. Graham Reed;Taeko Inoue

  245
  Citations

• Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis.

  Maria Capovilla;Mary Brandt;Juan Botas

  223
  Citations

• The AXH Domain of Ataxin-1 Mediates Neurodegeneration through Its Interaction with Gfi-1/Senseless Proteins

  Hiroshi Tsuda;Hamed Jafar-Nejad;Akash J. Patel;Yaling Sun

  215
  Citations

• The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll

  Elizabeth Eldon;Sandra Kooyer;Diana D'Evelyn;Molly Duman

  209
  Citations

• CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation.

  Ismael Al-Ramahi;Ismael Al-Ramahi;Yung C. Lam;Hung Kai Chen;Beatrice De Gouyon

  208
  Citations

• Matrix Metalloproteinases Are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington's Disease

  John P. Miller;Jennifer Holcomb;Ismael Al-Ramahi;Maria de Haro

  201
  Citations

• MBNL1 and CUGBP1 modify expanded CUG-induced toxicity in a Drosophila model of myotonic dystrophy type 1.

  María de Haro;Ismael Al-Ramahi;Beatrice De Gouyon;Lubna Ukani

  193
  Citations

• Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm.

  Eliana Romero;Guang-Ho Cha;Patrik Verstreken;Cindy V. Ly

  192
  Citations

• Gene-dose titration analysis in the search of trans-regulatory genes in Drosophila.

  J. Botas;J. Moscoso del Prado;Antonio García-Bellido

  174
  Citations

• Control of morphogenesis and differentiation by HOM/Hox genes

  Juan Botas

  174
  Citations