Her scientific interests lie mostly in Caspase, Huntingtin, Molecular biology, Cell biology and Huntingtin Protein. Her research integrates issues of Nuclear export signal, Proteolytic enzymes, Calpain and Neurodegeneration in her study of Huntingtin. Her Cell biology research includes themes of Apoptosis and Programmed cell death.
Her work carried out in the field of Programmed cell death brings together such families of science as Unfolded protein response and Endoplasmic reticulum. Her Huntingtin Protein research integrates issues from Exon, Cytoplasm, Cell nucleus and Model organism. Her study looks at the intersection of Polyglutamine tract and topics like Cleavage with Mutant and Human brain.
Cell biology, Huntingtin, Huntington's disease, Molecular biology and Biochemistry are her primary areas of study. Her biological study spans a wide range of topics, including Caspase, Apoptosis, Programmed cell death and Spinocerebellar ataxia. Her work deals with themes such as Proteases, Cleavage and Proteolysis, which intersect with Caspase.
Lisa M. Ellerby specializes in Huntingtin, namely Huntingtin Protein. The concepts of her Huntington's disease study are interwoven with issues in Stem cell, Neuroscience, Neuroprotection and Induced pluripotent stem cell. Her Molecular biology research incorporates elements of Mutant, Neurodegeneration, Calpain, Polyglutamine tract and Genetically modified mouse.
Lisa M. Ellerby mainly focuses on Cell biology, Huntington's disease, Neuroscience, Huntingtin and Disease. As part of her studies on Cell biology, Lisa M. Ellerby often connects relevant subjects like GABAergic. Her studies deal with areas such as Neurodegeneration and Neural stem cell as well as Huntington's disease.
Her Neuroscience study combines topics in areas such as Enhancer and Transcription factor. Her Huntingtin research includes elements of Transcription and DNA repair. Lisa M. Ellerby has included themes like Phenotype, Induced pluripotent stem cell and Organoid in her Disease study.
Her primary areas of investigation include Cell biology, Huntington's disease, Huntingtin, Neurodegeneration and Cell function. The Signal transduction research Lisa M. Ellerby does as part of her general Cell biology study is frequently linked to other disciplines of science, such as Striosome, therefore creating a link between diverse domains of science. Her Huntington's disease study combines topics from a wide range of disciplines, such as Neurotoxicity, Neuroprotection, Stem cell, Matrix metalloproteinase and Transforming growth factor beta.
Her Huntingtin study integrates concerns from other disciplines, such as Ubiquitin, DNA, DNA damage, DNA repair and CREB. Her Neurodegeneration study incorporates themes from Unfolded protein response, Proteostasis, Protein aggregation and Proteasome. Her study in Cell function is interdisciplinary in nature, drawing from both Selective vulnerability, Neuroscience, Phenotype, Disease and Induced pluripotent stem cell.
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Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Bax directly induces release of cytochrome c from isolated mitochondria
Juliane M. Jürgensmeier;Zhihua Xie;Quinn Deveraux;Lisa Ellerby.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Lysosomal Protease Pathways to Apoptosis: CLEAVAGE OF Bid, NOT PRO-CASPASES, IS THE MOST LIKELY ROUTE *
Veronika Stoka;Veronika Stoka;Boris Turk;Sharon L. Schendel;Tae Hyoung Kim.
Journal of Biological Chemistry (2001)
Coupling Endoplasmic Reticulum Stress to the Cell Death Program MECHANISM OF CASPASE ACTIVATION
Rammohan V. Rao;Evan Hermel;Susana Castro-Obregon;Gabriel del Rio.
Journal of Biological Chemistry (2001)
Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo: A Novel Therapy for Parkinson's Disease
Deepinder Kaur;Ferda Yantiri;Subramanian Rajagopalan;Jyothi Kumar.
Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78
Rammohan V. Rao;Alyson Peel;Anna Logvinova;Gabriel del Rio.
FEBS Letters (2002)
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia
Stanislaw Krajewski;Maryla Krajewska;Lisa M. Ellerby;Kate Welsh.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
Linda S. Kaltenbach;Eliana Romero;Robert R. Becklin;Rakesh Chettier.
PLOS Genetics (2007)
Caspase Cleavage of Mutant Huntingtin Precedes Neurodegeneration in Huntington's Disease
Cheryl L. Wellington;Lisa M. Ellerby;Claire-Anne Gutekunst;Danny Rogers.
The Journal of Neuroscience (2002)
Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells.
Cheryl L. Wellington;Roshni Singaraja;Lisa Ellerby;Jane Savill.
Journal of Biological Chemistry (2000)
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