What is she best known for?
The fields of study she is best known for:
Her scientific interests lie mostly in Caspase, Huntingtin, Molecular biology, Cell biology and Huntingtin Protein.
Her research integrates issues of Nuclear export signal, Proteolytic enzymes, Calpain and Neurodegeneration in her study of Huntingtin.
Her Cell biology research includes themes of Apoptosis and Programmed cell death.
Her work carried out in the field of Programmed cell death brings together such families of science as Unfolded protein response and Endoplasmic reticulum.
Her Huntingtin Protein research integrates issues from Exon, Cytoplasm, Cell nucleus and Model organism.
Her study looks at the intersection of Polyglutamine tract and topics like Cleavage with Mutant and Human brain.
Her most cited work include:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)
- Bax directly induces release of cytochrome c from isolated mitochondria (1390 citations)
- Lysosomal Protease Pathways to Apoptosis: CLEAVAGE OF Bid, NOT PRO-CASPASES, IS THE MOST LIKELY ROUTE * (608 citations)
What are the main themes of her work throughout her whole career to date?
Cell biology, Huntingtin, Huntington's disease, Molecular biology and Biochemistry are her primary areas of study.
Her biological study spans a wide range of topics, including Caspase, Apoptosis, Programmed cell death and Spinocerebellar ataxia.
Her work deals with themes such as Proteases, Cleavage and Proteolysis, which intersect with Caspase.
Lisa M. Ellerby specializes in Huntingtin, namely Huntingtin Protein.
The concepts of her Huntington's disease study are interwoven with issues in Stem cell, Neuroscience, Neuroprotection and Induced pluripotent stem cell.
Her Molecular biology research incorporates elements of Mutant, Neurodegeneration, Calpain, Polyglutamine tract and Genetically modified mouse.
She most often published in these fields:
- Cell biology (37.74%)
- Huntingtin (31.13%)
- Huntington's disease (25.47%)
What were the highlights of her more recent work (between 2017-2021)?
- Cell biology (37.74%)
- Huntington's disease (25.47%)
- Neuroscience (14.15%)
In recent papers she was focusing on the following fields of study:
Lisa M. Ellerby mainly focuses on Cell biology, Huntington's disease, Neuroscience, Huntingtin and Disease.
As part of her studies on Cell biology, Lisa M. Ellerby often connects relevant subjects like GABAergic.
Her studies deal with areas such as Neurodegeneration and Neural stem cell as well as Huntington's disease.
Her Neuroscience study combines topics in areas such as Enhancer and Transcription factor.
Her Huntingtin research includes elements of Transcription and DNA repair.
Lisa M. Ellerby has included themes like Phenotype, Induced pluripotent stem cell and Organoid in her Disease study.
Between 2017 and 2021, her most popular works were:
- Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription (33 citations)
- Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates (12 citations)
- Modeling Polyglutamine Expansion Diseases with Induced Pluripotent Stem Cells. (12 citations)
In her most recent research, the most cited papers focused on:
Her primary areas of investigation include Cell biology, Huntington's disease, Huntingtin, Neurodegeneration and Cell function.
The Signal transduction research Lisa M. Ellerby does as part of her general Cell biology study is frequently linked to other disciplines of science, such as Striosome, therefore creating a link between diverse domains of science.
Her Huntington's disease study combines topics from a wide range of disciplines, such as Neurotoxicity, Neuroprotection, Stem cell, Matrix metalloproteinase and Transforming growth factor beta.
Her Huntingtin study integrates concerns from other disciplines, such as Ubiquitin, DNA, DNA damage, DNA repair and CREB.
Her Neurodegeneration study incorporates themes from Unfolded protein response, Proteostasis, Protein aggregation and Proteasome.
Her study in Cell function is interdisciplinary in nature, drawing from both Selective vulnerability, Neuroscience, Phenotype, Disease and Induced pluripotent stem cell.
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