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Biology and Biochemistry

D-Index
71
Citations
20138
World Ranking
6579
National Ranking
3063

Overview

Birgit Schilling is affiliated with the Buck Institute for Research on Aging in the United States. Their research spans fields including Biochemistry, Genetics and Molecular Biology, and Medicine, with a substantial publication record comprising 205 works in biochemistry-related disciplines and 168 in medical sciences.

Their subfields of focus feature Molecular Biology, Physiology, Spectroscopy, Aging, and Geriatrics and Gerontology. These areas underscore a broad engagement with biological processes at molecular and systemic levels, particularly those related to the biology of aging.

Schilling's work addresses several main topics, notably:

  • Telomeres, Telomerase, and Senescence
  • Genetics, Aging, and Longevity in Model Organisms
  • Advanced Proteomics Techniques and Applications
  • Sirtuins and Resveratrol in Medicine
  • Adipose Tissue and Metabolism
  • Mass Spectrometry Techniques and Applications
  • Mitochondrial Function and Pathology

Their frequent collaborators include Joanna Bons, Jacob Rose, Nathan Basisty, Judith Campisi, and Samah Shah, indicating active partnerships in the research community.

Schilling has published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), with 55 publications, Innovation in Aging, Aging Cell, GeroScience, and Aging. These journals reflect the focus on aging and molecular biology research.

Notable recent papers include:

  • A proteomic atlas of senescence-associated secretomes for aging biomarker development, 2020, PLoS Biology
  • MicroRNA sequence codes for small extracellular vesicle release and cellular retention, 2021, Nature
  • Skyline for Small Molecules: A Unifying Software Package for Quantitative Metabolomics, 2020, Journal of Proteome Research
  • Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages, 2020, Nature Metabolism
  • SenNet recommendations for detecting senescent cells in different tissues, 2024, Nature Reviews Molecular Cell Biology

Best Publications

  • Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

    Terri A. Addona;Susan E. Abbatiello;Birgit Schilling;Steven J. Skates

  • A proteomic atlas of senescence-associated secretomes for aging biomarker development.

    Nathan Basisty;Abhijit Kale;Ok Hee Jeon;Chisaka Kuehnemann

  • Repeatability and Reproducibility in Proteomic Identifications by Liquid Chromatography−Tandem Mass Spectrometry

    David L. Tabb;Lorenzo Vega-Montoto;Lorenzo Vega-Montoto;Paul A. Rudnick;Asokan Mulayath Variyath;Asokan Mulayath Variyath

  • Skyline for Small Molecules: A Unifying Software Package for Quantitative Metabolomics

    Kendra J. Adams;Brian Pratt;Neelanjan Bose;Laura G. Dubois

  • Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry

    Ben C. Collins;Christie L. Hunter;Yansheng Liu;Birgit Schilling

  • Platform-independent and Label-free Quantitation of Proteomic Data Using MS1 Extracted Ion Chromatograms in Skyline APPLICATION TO PROTEIN ACETYLATION AND PHOSPHORYLATION

    Birgit Schilling;Matthew J. Rardin;Brendan X. MacLean;Anna M. Zawadzka

  • Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

    Sang-Won Min;Xu Chen;Tara E Tracy;Yaqiao Li

  • Interaction with Podocin Facilitates Nephrin Signaling

    Tobias B. Huber;Michael Köttgen;Birgit Schilling;Gerd Walz

  • Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

    Matthew J. Rardin;John C. Newman;Jason M. Held;Michael P. Cusack

  • Mitochondrial oxidative stress causes hyperphosphorylation of tau.

    Simon Melov;Paul A. Adlard;Karl Morten;Felicity Johnson

  • IDPicker 2.0: Improved protein assembly with high discrimination peptide identification filtering.

    Ze Qiang Ma;Surendra Dasari;Matthew C. Chambers;Michael D. Litton

  • MS2Assign, automated assignment and nomenclature of tandem mass spectra of chemically crosslinked peptides

    Birgit Schilling;Richard H. Row;Bradford W. Gibson;Xin Guo

  • Phosphospecific proteolysis for mapping sites of protein phosphorylation

    Zachary A Knight;Birgit Schilling;Richard H Row;Denise M Kenski

  • Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.

    Misty L. Kuhn;Bozena Zemaitaitis;Linda I. Hu;Alexandria Sahu

  • Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages.

    Anthony J. Covarrubias;Anthony J. Covarrubias;Abhijit Kale;Rosalba Perrone;Jose Alberto Lopez-Dominguez

  • Panorama Public: A Public Repository for Quantitative Data Sets Processed in Skyline.

    Vagisha Sharma;Josh Eckels;Birgit Schilling;Christina Ludwig

  • Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter

    Sukkid Yasothornsrikul;Doron Greenbaum;Katalin F. Medzihradszky;Thomas Toneff

  • Panorama: a targeted proteomics knowledge base.

    Vagisha Sharma;Josh Eckels;Greg K. Taylor;Nicholas J. Shulman

  • Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss

    Tara E. Tracy;Peter Dongmin Sohn;S. Sakura Minami;Chao Wang

  • Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation

    Ulrike Bruning;Ulrike Bruning;Francisco Morales-Rodriguez;Joanna Kalucka;Jermaine Goveia

Frequent Co-Authors

Bradford W. Gibson
Bradford W. Gibson Buck Institute for Research on Aging
Christopher C. Benz
Christopher C. Benz Buck Institute for Research on Aging
Judith Campisi
Judith Campisi Buck Institute for Research on Aging
Susan J. Fisher
Susan J. Fisher University of California, San Francisco
Eric Verdin
Eric Verdin Buck Institute for Research on Aging
Brendan MacLean
Brendan MacLean University of Washington
Steven A. Carr
Steven A. Carr Broad Institute
Amanda G. Paulovich
Amanda G. Paulovich Fred Hutchinson Cancer Research Center
daniel c liebler
daniel c liebler Vanderbilt University
Michael J. MacCoss
Michael J. MacCoss University of Washington

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