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D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
28672
World Ranking
6143
National Ranking
2883

Overview

Richard K. Assoian is affiliated with the University of Pennsylvania in the United States. Their research spans several fields within the biological sciences, focusing primarily on biochemistry, genetics, and molecular biology, with additional work in medicine.

The main fields of study reflecting their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

More specifically, their subfields of study comprise:

  • Molecular Biology
  • Cell Biology
  • Surgery
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

The core topics addressed in their research cover diverse areas such as:

  • Cellular Mechanics and Interactions
  • Cell Adhesion Molecules Research
  • Mitochondrial Function and Pathology
  • RNA Research and Splicing
  • Metabolomics and Mass Spectrometry Studies
  • Nuclear Structure and Function
  • Pediatric Hepatobiliary Diseases and Treatments

Assoian has contributed to several recent publications, including:

  • Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure (2022, Cell Metabolism)
  • Endothelial lipid droplets suppress eNOS to link high fat consumption to blood pressure elevation (2023, Journal of Clinical Investigation)
  • Mechanosensitive smooth muscle cell phenotypic plasticity emerging from a null state and the balance between Rac and Rho (2021, Cell Reports)
  • Arterial stiffness and cardiac dysfunction in Hutchinson-Gilford Progeria Syndrome corrected by inhibition of lysyl oxidase (2021, Life Science Alliance)
  • Fibroblast Activation Protein Regulates Lesion Burden and the Fibroinflammatory Response in Apoe-Deficient Mice in a Sexually Dimorphic Manner (2020, American Journal Of Pathology)

Their work has been published frequently in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Cell Metabolism
  • Journal of Clinical Investigation
  • Cell Reports

Richard K. Assoian collaborates regularly with several researchers, including:

  • Emilia Roberts
  • Tina Xu
  • Michael G. Levin
  • Boa Kim
  • Zoltàn Arany

Best Publications

  • Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

    A B Roberts;M B Sporn;R K Assoian;J M Smith

  • Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells.

    Rik Derynck;Julie A. Jarrett;Ellson Y. Chen;Dennis H. Eaton

  • Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

    R K Assoian;A Komoriya;C A Meyers;D M Miller

  • Transforming growth factor-beta: biological function and chemical structure

    Michael B. Sporn;Anita B. Roberts;Lalage M. Wakefield;Richard K. Assoian

  • Expression and secretion of type beta transforming growth factor by activated human macrophages

    Richard K. Assoian;Barbara E. Fleurdelys;Henry C. Stevenson;Paul J. Miller

  • Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells.

    Richard K. Assoian;Michael B. Sporn

  • Integrins and cell proliferation: regulation of cyclin-dependent kinases via cytoplasmic signaling pathways.

    Martin Alexander Schwartz;Richard K. Assoian

  • Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes.

    M P Stoppelli;A Corti;A Soffientini;G Cassani

  • Integrating the MAP kinase signal into the G1 phase cell cycle machinery.

    Kristin Roovers;Richard K. Assoian

  • Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein.

    X Zhu;M Ohtsubo;R M Böhmer;J M Roberts

  • Cellular transformation by coordinated action of three peptide growth factors from human platelets

    Richard K. Assoian;Gary R. Grotendorst;Dorothea M. Miller;Michael B. Sporn

  • Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation.

    Xiaoyun Zhu;R. K. Assoian

  • A link between cyclin A expression and adhesion-dependent cell cycle progression

    Thomas M. Guadagno;Motoaki Ohtsubo;James M. Roberts;Richard K. Assoian

  • Anchorage-dependent Cell Cycle Progression

    Richard K. Assoian

  • Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

    Eric A. Klein;Liqun Yin;Devashish Kothapalli;Paola Castagnino

  • Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression

    Richard K Assoian;Martin A Schwartz

  • Induction of transforming growth factor-α in activated human alveolar macrophages

    David K. Madtes;Elaine W. Raines;Kjell S. Sakariassen;Richard K. Assoian

  • Transcriptional regulation of the cyclin D1 gene at a glance

    Eric A. Klein;Richard K. Assoian

  • Timing of cyclin D1 expression within G1 phase is controlled by Rho

    Catherine F. Welsh;Kristin Roovers;Jessie Villanueva;Yun Qi Liu

  • The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation

    Carolyn A. Cuff;Devashish Kothapalli;Ijeoma Azonobi;Sam Chun

Frequent Co-Authors

Ellen Puré
Ellen Puré University of Pennsylvania
Michael B. Sporn
Michael B. Sporn Dartmouth College
Kathleen J. Stebe
Kathleen J. Stebe University of Pennsylvania
Christopher S. Chen
Christopher S. Chen Boston University
Daniel J. Rader
Daniel J. Rader University of Pennsylvania
Paul A. Janmey
Paul A. Janmey University of Pennsylvania
Maria Elena Bottazzi
Maria Elena Bottazzi Baylor College of Medicine
Garret A. FitzGerald
Garret A. FitzGerald University of Pennsylvania
Anita B. Roberts
Anita B. Roberts National Institutes of Health
Marcelo G. Kazanietz
Marcelo G. Kazanietz University of Pennsylvania

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