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Biology and Biochemistry

D-Index
58
Citations
12859
World Ranking
13122
National Ranking
5597

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Robert Flaumenhaft is affiliated with the Beth Israel Deaconess Medical Center in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a notable focus on hematology, molecular biology, cell biology, physiology, and immunology.

The scientist's work extensively covers platelet disorders and treatments, blood coagulation and thrombosis mechanisms, endoplasmic reticulum stress and disease, blood properties and coagulation, venous thromboembolism diagnosis and management, antiplatelet therapy, cardiovascular diseases, and adenosine and purinergic signaling.

Frequent publication venues for their research include Blood, Journal of Thrombosis and Haemostasis, bioRxiv (Cold Spring Harbor Laboratory), The Cambridge Structural Database, and Blood Advances.

Several recent notable papers authored or co-authored by Robert Flaumenhaft include:

  • A polymer-based systemic hemostatic agent, 2020, Science Advances
  • PIEZO1 mediates a mechanothrombotic pathway in diabetes, 2022, Science Translational Medicine
  • Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19, 2021, JCI Insight
  • Platelet Dysfunction and Thrombosis in JAK2 V617F-Mutated Primary Myelofibrotic Mice, 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • Shining a light on SSP4: A comprehensive analysis and biological applications for the detection of sulfane sulfurs, 2022, Redox Biology

Frequent co-authors collaborated with Robert Flaumenhaft include Moua Yang, Glenn Merrill-Skoloff, Christina Scartelli, Kelsey D. Sack, and Nicola Pozzi, reflecting ongoing partnerships in advancing research in related fields.

The scientist has been recognized as a member of the Association of American Physicians, denoting standing within the medical research community.

Best Publications

  • Platelet α–granules: Basic biology and clinical correlates

    Price Blair;Robert Flaumenhaft

  • Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Required for P-Selectin–Mediated but Not E-Selectin–Mediated Neutrophil Rolling and Migration

    Jing Yang;Jing Yang;Takako Hirata;Takako Hirata;Kevin Croce;Kevin Croce;Glenn Merrill-Skoloff;Glenn Merrill-Skoloff

  • Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles

    Robert Flaumenhaft;James R. Dilks;Jennifer Richardson;Eva Alden

  • Clinical relevance of microparticles from platelets and megakaryocytes.

    Joseph E. Italiano;Albert T.A. Mairuhu;Robert Flaumenhaft

  • Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor.

    R Flaumenhaft;D Moscatelli;D B Rifkin

  • Role of extracellular matrix in the action of basic fibroblast growth factor: matrix as a source of growth factor for long-term stimulation of plasminogen activator production and DNA synthesis.

    Robert Flaumenhaft;David Moscatelli;Olli Saksela;Daniel B. Rifkin

  • A journey with platelet P-selectin: the molecular basis of granule secretion, signalling and cell adhesion.

    Bruce Furie;Barbara C. Furie;Robert Flaumenhaft

  • Role of the latent TGF-beta binding protein in the activation of latent TGF-beta by co-cultures of endothelial and smooth muscle cells.

    R Flaumenhaft;M Abe;Y Sato;K Miyazono

  • Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents

    Reema Jasuja;Freda H. Passam;Daniel R. Kennedy;Sarah H. Kim

  • Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics

    A. Jain;Riccardo Barrile;Riccardo Barrile;A.D. van der Meer;A. Mammoto

  • Basic fibroblast growth factor-induced activation of latent transforming growth factor beta in endothelial cells: regulation of plasminogen activator activity.

    R Flaumenhaft;M Abe;P Mignatti;D B Rifkin

  • Molecular Basis of Platelet Granule Secretion

    Robert Flaumenhaft

  • T granules in human platelets function in TLR9 organization and signaling

    Jonathan N. Thon;Christopher G. Peters;Kellie R. Machlus;Kellie R. Machlus;Rukhsana Aslam

  • The extracellular regulation of growth factor action.

    R Flaumenhaft;D B Rifkin

  • Formation and fate of platelet microparticles

    Robert Flaumenhaft

  • The actin cytoskeleton differentially regulates platelet α-granule and dense-granule secretion

    Robert Flaumenhaft;James R. Dilks;Nataliya Rozenvayn;Rita A. Monahan-Earley

  • Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4.

    Robert Flaumenhaft;Robert Flaumenhaft;Kevin Croce;Kevin Croce;Emy Chen;Bruce Furie

  • The life cycle of platelet granules.

    Anish Sharda;Robert Flaumenhaft

  • Extracellular matrix regulation of growth factor and protease activity

    Robert Flaumenhaft;Daniel B. Rifkin

  • A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function

    Abhishek Jain;Amanda Graveline;Anna Waterhouse;Andyna Vernet

Frequent Co-Authors

Bruce Furie
Bruce Furie Beth Israel Deaconess Medical Center
Joseph E. Italiano
Joseph E. Italiano Boston Children's Hospital
Daniel B. Rifkin
Daniel B. Rifkin New York University
Donald E. Ingber
Donald E. Ingber Harvard University
Mingdong Huang
Mingdong Huang Fuzhou University
Ann M. Dvorak
Ann M. Dvorak Beth Israel Deaconess Medical Center
John V. Frangioni
John V. Frangioni Beth Israel Deaconess Medical Center
David Moscatelli
David Moscatelli New York University
Philip J. Hogg
Philip J. Hogg Centenary Institute of Cancer Medicine and Cell Biology
Donna Neuberg
Donna Neuberg Harvard University

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