His scientific interests lie mostly in Biochemistry, Cell biology, N-Ethylmaleimide-Sensitive Proteins, Lipid bilayer fusion and N-ethylmaleimide sensitive fusion protein. As a part of the same scientific study, Sidney W. Whiteheart usually deals with the Biochemistry, concentrating on Biophysics and frequently concerns with Lipid bilayer. His research in Cell biology intersects with topics in Exocytosis, Secretion, Vesicle docking, Synaptic vesicle docking and Membrane protein.
Sidney W. Whiteheart works mostly in the field of N-Ethylmaleimide-Sensitive Proteins, limiting it down to topics relating to Binding site and, in certain cases, SNARE complex disassembly. Fusion protein and Soluble NSF attachment protein are the subject areas of his N-ethylmaleimide sensitive fusion protein study. In Soluble NSF attachment protein, Sidney W. Whiteheart works on issues like Vesicle-associated membrane protein, which are connected to Complexin, Synaptotagmin 1, Synaptic vesicle membrane, Kiss-and-run fusion and Vesicle fusion.
His main research concerns Cell biology, Platelet, Biochemistry, Platelet activation and Secretion. His research integrates issues of Lipid bilayer fusion, Soluble NSF attachment protein, Exocytosis, Membrane protein and Syntaxin in his study of Cell biology. His work in Lipid bilayer fusion tackles topics such as Vesicle which are related to areas like Neurotransmitter.
His studies in Soluble NSF attachment protein integrate themes in fields like AAA proteins, N-Ethylmaleimide-Sensitive Proteins and Vesicle-associated membrane protein. The concepts of his Platelet study are interwoven with issues in Hemostasis and Granule. The various areas that Sidney W. Whiteheart examines in his Biochemistry study include Biophysics and Fusion protein.
His primary areas of investigation include Platelet, Cell biology, Platelet activation, Hemostasis and Granule. His Platelet research is multidisciplinary, incorporating perspectives in Thrombosis, Endocytosis and Secretion. His study in Cell biology is interdisciplinary in nature, drawing from both Receptor and Platelet exocytosis.
His Granule study integrates concerns from other disciplines, such as Biophysics and Alpha Granule. Sidney W. Whiteheart usually deals with Hematology and limits it to topics linked to Platelet secretion and Biochemistry. His study in the field of Soluble NSF attachment protein is also linked to topics like Tubulin.
Sidney W. Whiteheart mainly focuses on Platelet, Endocytosis, Receptor, Cell biology and Endocytic cycle. The Platelet study combines topics in areas such as Hemostasis, Secretion, Integrin and In vivo. His Secretion research incorporates themes from Rab and Phosphorylation.
His Endocytosis research includes elements of Inflammation, Immunology and Viremia. His work deals with themes such as Clot retraction, P2Y12, Purinergic receptor and Signal transduction, which intersect with Endocytic cycle. Sidney W. Whiteheart works in the field of Lipid bilayer fusion, namely Soluble NSF attachment protein.
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SNAP receptors implicated in vesicle targeting and fusion
Thomas Söllner;Sidney W. Whiteheart;Michael Brunner;Hediye Erdjument-Bromage.
Nature (1993)
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
Thomas Söllner;Mark K. Bennett;Sidney W. Whiteheart;Richard H. Scheller.
Cell (1993)
AAA+ proteins: have engine, will work.
Phyllis I. Hanson;Sidney W. Whiteheart.
Nature Reviews Molecular Cell Biology (2005)
N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion.
S W Whiteheart;K Rossnagel;S A Buhrow;M Brunner.
Journal of Cell Biology (1994)
Crystal structure of the hexamerization domain of N-ethylmaleimide-sensitive fusion protein.
Christian U. Lenzen;Diana Steinmann;Sidney W. Whiteheart;William I. Weis.
Cell (1998)
A multisubunit particle implicated in membrane fusion.
D W Wilson;S W Whiteheart;M Wiedmann;M Brunner.
Journal of Cell Biology (1992)
Conserved arginine residues implicated in ATP hydrolysis, nucleotide-sensing, and inter-subunit interactions in AAA and AAA+ ATPases
Teru Ogura;Sidney W Whiteheart;Anthony J Wilkinson.
Journal of Structural Biology (2004)
SNAP family of NSF attachment proteins includes a brain-specific isoform
Sidney W. Whiteheart;Irene C. Griff;Michael Brunner;Douglas O. Clary;Douglas O. Clary.
Nature (1993)
TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation
Priyanka Nair-Gupta;Alessia Baccarini;Navpreet Tung;Fabian Seyffer.
Cell (2014)
The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells.
Seng Hui Low;Steven J. Chapin;Christian Wimmer;Sidney W. Whiteheart.
Journal of Cell Biology (1998)
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