Paul A. Roche

Overview

Best Publications

• The ins and outs of MHC class II-mediated antigen processing and presentation

  Paul A. Roche;Kazuyuki Furuta

  1017
  Citations

• Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

  Paul A. Roche;Peter Cresswell

  672
  Citations

• Macropinocytosis in phagocytes: regulation of MHC class-II-restricted antigen presentation in dendritic cells.

  Zhenzhen Liu;Paul A. Roche

  537
  Citations

• Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain.

  Paul A. Roche;Michael S. Marks;Michael S. Marks;Peter J. Cresswell

  439
  Citations

• Identification of a Novel Syntaxin- and Synaptobrevin/VAMP-binding Protein, SNAP-23, Expressed in Non-neuronal Tissues

  Veerasamy Ravichandran;Ashish Chawla;Paul A. Roche

  408
  Citations

• Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation.

  Howard A. Anderson;Elizabeth M. Hiltbold;Paul A. Roche

  401
  Citations

• Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients.

  Yenan T. Bryceson;Yenan T. Bryceson;Eva Rudd;Chengyun Y. Zheng;Josefine Edner

  368
  Citations

• TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation

  Priyanka Nair-Gupta;Alessia Baccarini;Navpreet Tung;Fabian Seyffer

  364
  Citations

• T cell-induced secretion of MHC class II–peptide complexes on B cell exosomes

  Aura Muntasell;Adam C Berger;Paul A Roche

  314
  Citations

• Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules.

  Paul A. Roche;Peter Cresswell

  312
  Citations

• Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization

  Paul A. Roche;Christina L. Teletski;Espen Stang;Oddmund Bakke

  296
  Citations

• Suppression of antigen presentation by IL-10.

  Sharad K Mittal;Paul A Roche

  271
  Citations

• Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms

  Niti Puri;Paul A. Roche

  246
  Citations

• A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.

  M S Marks;P A Roche;E van Donselaar;L Woodruff

  242
  Citations

• High-affinity binding of an influenza hemagglutinin-derived peptide to purified HLA-DR.

  P A Roche;P Cresswell

  201
  Citations

• Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis

  Harald F. Langer;Kyoung-Jin Chung;Kyoung-Jin Chung;Valeria V. Orlova;Eun Young Choi

  196
  Citations

• HIV-1 Tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes

  J. D. Weissman;J. A. Brown;T. K. Howcroft;Jae Hwang

  190
  Citations

• Internalization and catabolism of radiolabelled antibodies to the MHC class-II invariant chain by B-cell lymphomas.

  Hans J Hansen;Gaik Lin Ong;Habibe Diril;Anita Valdez

  187
  Citations

• Trafficking of MHC class II molecules in the late secretory pathway.

  Elizabeth M Hiltbold;Paul A Roche

  168
  Citations

• A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking

  Young Ho Suh;Akira Terashima;Ronald S Petralia;Robert J Wenthold

  165
  Citations