2026 Gary Thomas: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	64	9627	8886	4252	3821	109	15230

Overview

Gary Thomas is affiliated with the University of Pittsburgh in the United States. Their research spans multiple areas of biochemistry, genetics, molecular biology, and medicine, focusing on subfields such as molecular biology, cell biology, genetics, physiology, and epidemiology.

The main topics addressed in Gary Thomas's work include:

Endoplasmic Reticulum Stress and Disease
Genetics and Neurodevelopmental Disorders
Mitochondrial Function and Pathology
Cellular transport and secretion
Autophagy in Disease and Therapy
SARS-CoV-2 and COVID-19 Research
Cancer-related gene regulation

Gary Thomas has published research in various scientific journals, with notable publication venues including:

Biology Direct
International Journal of Molecular Sciences
Proceedings of the National Academy of Sciences
Nature Communications
Oncogene

Selected recent papers authored or co-authored by Gary Thomas include:

"The multifunctional protein PACS-1 is required for HDAC2- and HDAC3-dependent chromatin maturation and genomic stability" (2020, Oncogene)
"Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins" (2021, Biology Direct)
"The Path to Therapeutic Furin Inhibitors: From Yeast Pheromones to SARS-CoV-2" (2022, International Journal of Molecular Sciences)
"Genome-wide kinase-MAM interactome screening reveals the role of CK2A1 in MAM Ca²⁺ dynamics linked to DEE66" (2023, Proceedings of the National Academy of Sciences)
"Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy" (2023, Nature Communications)

Frequent collaborators in their research include:

Yunhan Yang
Thomas Simmen
Laurel Thomas
Kun Chen
Jenea Barbara Lyles

Best Publications

Furin at the cutting edge: from protein traffic to embryogenesis and disease.

Gary Thomas

1668
Citations
Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin

Kurt R. Klimpel;Sean S. Molloy;Gary Thomas;Stephen H. Leppla

708
Citations
Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface.

S.S. Molloy;L. Thomas;J.K. VanSlyke;P.E. Stenberg

687
Citations
PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis.

Thomas Simmen;Joseph E. Aslan;Anastassia D. Blagoveshchenskaya;Laurel Thomas

600
Citations
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo.

Patricia A. Bresnahan;Richard Leduc;Laurel Thomas;Jeremy Thorner

491
Citations
Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis.

Sean S. Molloy;Eric D. Anderson;François Jean;Gary Thomas

468
Citations
PACS-1 Defines a Novel Gene Family of Cytosolic Sorting Proteins Required for trans-Golgi Network Localization

Lei Wan;Sean S. Molloy;Laurel Thomas;Gseping Liu

450
Citations
HIV-1 Nef Downregulates MHC-I by a PACS-1- and PI3K-Regulated ARF6 Endocytic Pathway

Anastassia D Blagoveshchenskaya;Laurel Thomas;Sylvain F Feliciangeli;Chien Hui Hung

433
Citations
KEX2-LIKE ENDOPROTEASES PC2 AND PC3 ACCURATELY CLEAVE A MODEL PROHORMONE IN MAMMALIAN CELLS : EVIDENCE FOR A COMMON CORE OF NEUROENDOCRINE PROCESSING ENZYMES

Laurel Thomas;Richard Leduc;Barbara A. Thorne;Steven P. Smeekens

424
Citations
HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

Vincent Piguet;Lei Wan;Christelle Borel;Aram Mangasarian

383
Citations
α1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: Application as an antipathogenic agent

François Jean;Kori Stella;Laurel Thomas;Gseping Liu

343
Citations
BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development

Yanzhen Cui;François Jean;Gary Thomas;Jan L. Christian

319
Citations
Activation of the furin endoprotease is a multiple‐step process: requirements for acidification and internal propeptide cleavage

Eric D. Anderson;Judy K. VanSlyke;Craig D. Thulin;François Jean

284
Citations
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.

Michael Köttgen;Thomas Benzing;Thomas Simmen;Robert Tauber

272
Citations
Trans-Golgi network sorting.

F. Gu;C.M. Crump;G. Thomas

268
Citations
Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells

Gary Thomas;Barbara A. Thorne;Laurel Thomas;Richard G. Allen

249
Citations
The Subcellular Distribution of Calnexin Is Mediated by PACS-2

Nathan Myhill;Emily M. Lynes;Jalal A. Nanji;Anastassia D. Blagoveshchenskaya

248
Citations
Interaction of furin in immature secretory granules from neuroendocrine cells with the AP-1 adaptor complex is modulated by casein kinase II phosphorylation.

Andrea S. Dittié;Laurel Thomas;Gary Thomas;Sharon A. Tooze

247
Citations
Oxidative Protein Folding in the Endoplasmic Reticulum: Tight Links to the Mitochondria-Associated Membrane (MAM)

Thomas Simmen;Emily M. Lynes;Kevin Gesson;Gary Thomas

236
Citations
PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic

Colin M. Crump;Yang Kevin Xiang;Laurel Thomas;Feng Gu

235
Citations