Dennis E. Hruby

Overview

Best Publications

• An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

  Guang Yang;Daniel C. Pevear;Marc H. Davies;Marc S. Collett

  526
  Citations

• Severe Eczema Vaccinatum in a Household Contact of a Smallpox Vaccinee

  Surabhi Vora;Inger Damon;Vincent Fulginiti;Vincent Fulginiti;Stephen G. Weber

  258
  Citations

• Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells

  Gary Thomas;Barbara A. Thorne;Laurel Thomas;Richard G. Allen

  249
  Citations

• Nonhuman Primates Are Protected from Smallpox Virus or Monkeypox Virus Challenges by the Antiviral Drug ST-246

  John Huggins;Arthur Goff;Lisa Hensley;Eric Mucker

  206
  Citations

• Neomycin resistance as a dominant selectable marker for selection and isolation of vaccinia virus recombinants.

  Christine A. Franke;Charles M. Rice;James H. Strauss;Dennis E. Hruby

  196
  Citations

• Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector.

  R H Edwards;M J Selby;W C Mobley;S L Weinrich

  175
  Citations

• Inactivation of the srtA Gene in Streptococcus gordonii Inhibits Cell Wall Anchoring of Surface Proteins and Decreases In Vitro and In Vivo Adhesion

  Tové C. Bolken;Christine A. Franke;Kevin F. Jones;Gloria O. Zeller

  151
  Citations

• Chlamydia psittaci IncA is phosphorylated by the host cell and is exposed on the cytoplasmic face of the developing inclusion

  D. D. Rockey;D. Grosenbach;D. E. Hruby;M. G. Peacock

  147
  Citations

• Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions.

  Charles M. Rice;Christine A. Franke;James H. Strauss;Dennis E. Hruby

  144
  Citations

• Pox proteomics: mass spectrometry analysis and identification of Vaccinia virion proteins

  Jennifer D Yoder;Tsefang S Chen;Cliff R Gagnier;Srilakshmi Vemulapalli

  141
  Citations

• Insertional inactivation of the large subunit of ribonucleotide reductase encoded by vaccinia virus is associated with reduced virulence in vivo

  S. J. Child;G. J. Palumbo;R. M. L. Buller;D. E. Hruby

  134
  Citations

• Conditional lethal expression of the vaccinia virus L1R myristylated protein reveals a role in virion assembly.

  M P Ravanello;D E Hruby

  132
  Citations

• Progressive Vaccinia: Case Description and Laboratory-Guided Therapy With Vaccinia Immune Globulin, ST-246, and CMX001

  Edith R. Lederman;Edith R. Lederman;Whitni Davidson;Harold L. Groff;Scott K. Smith

  128
  Citations

• The multistep proteolytic maturation pathway utilized by vaccinia virus P4a protein: a degenerate conserved cleavage motif within core proteins.

  Judy K. Vanslyke;Stephen S. Whitehead;Elizabeth M. Wilson;Dennis E. Hruby

  117
  Citations

• Development of the small-molecule antiviral ST-246 as a smallpox therapeutic.

  Douglas W Grosenbach;Robert Jordan;Dennis E Hruby

  115
  Citations

• Expression and cell type--specific processing of human preproenkephalin with a vaccinia recombinant.

  Gary Thomas;Edward Herbert;Dennis E. Hruby

  112
  Citations

• Development of ST-246® for Treatment of Poxvirus Infections.

  Robert Jordan;Janet M. Leeds;Shanthakumar Tyavanagimatt;Dennis E. Hruby

  109
  Citations

• The Vaccinia Virus I7L Gene Product Is The Core Protein Proteinase

  Chelsea M. Byrd;Tove' C. Bolken;Dennis E. Hruby;Dennis E. Hruby

  108
  Citations

• Conserved DegP Protease in Gram-Positive Bacteria Is Essential for Thermal and Oxidative Tolerance and Full Virulence in Streptococcus pyogenes

  C. Hal Jones;Tove' C. Bolken;Kevin F. Jones;Gloria O. Zeller

  108
  Citations

• Interaction of GRASP, a Protein encoded by a Novel Retinoic Acid-induced Gene, with Members of the Cytohesin Family of Guanine Nucleotide Exchange Factors

  Daniel J. Nevrivy;Valerie J. Peterson;Dorina Avram;Jane E. Ishmael

  106
  Citations