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D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
19968
World Ranking
5592
National Ranking
404

Overview

Robert Feil is a researcher affiliated with the University of Tübingen in Germany. Their work spans multiple interconnected fields within biomedical science, focusing primarily on mechanisms relevant to cardiovascular and molecular biology.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader areas, Robert Feil's research delves into several subfields such as:

  • Molecular Biology
  • Cardiology and Cardiovascular Medicine
  • Immunology
  • Physiology
  • Hematology

The scientist's work particularly concentrates on key topics like:

  • Phosphodiesterase function and regulation
  • Nitric Oxide and Endothelin Effects
  • Receptor Mechanisms and Signaling
  • Platelet Disorders and Treatments
  • Atherosclerosis and Cardiovascular Diseases
  • Complement system in diseases
  • Renin-Angiotensin System Studies

Recent publications highlight their contributions to pharmacology and cardiovascular research. Notable papers include:

  • "Visualising and understanding cGMP signals in the cardiovascular system" (2021), published in British Journal of Pharmacology
  • "The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets" (2021), published in Nature Communications
  • "Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney" (2021), published in British Journal of Pharmacology
  • "Olinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso-occlusion and nephropathy in mouse models of sickle cell disease" (2021), published in British Journal of Pharmacology
  • "Heterogeneity of cGMP signalling in tumour cells and the tumour microenvironment: Challenges and chances for cancer pharmacology and therapeutics" (2023), published in Pharmacology & Therapeutics

Robert Feil's frequent co-authors include:

  • Susanne Feil
  • Daniel Stehle
  • Moritz Lehners
  • Tilman E. Schäffer
  • Manuela Sauter

Their contributions have been published mainly in venues such as:

  • British Journal of Pharmacology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Circulation Research
  • Blood

Best Publications

  • Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains.

    Robert Feil;Jürgen Wagner;Daniel Metzger;Pierre Chambon

  • LIGAND-ACTIVATED SITE-SPECIFIC RECOMBINATION IN MICE

    R Feil;J Brocard;B Mascrez;M LeMeur

  • Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

    Andreas Ludwig;Thomas Budde;Juliane Stieber;Sven Moosmang

  • Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis

    Susanne Feil;Birgit Fehrenbacher;Robert Lukowski;Frank Essmann

  • The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart

    Juliane Stieber;Stefan Herrmann;Susanne Feil;Jana Löster

  • Function of cGMP-Dependent Protein Kinases as Revealed by Gene Deletion

    F. Hofmann;R. Feil;T. Kleppisch;Jens Schlossmann

  • Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency

    M. Sausbier;H. Hu;C. Arntz;S. Feil

  • Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

    Kamran Ghoreschi;Jürgen Brück;Christina Kellerer;Caishu Deng

  • Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging

    Petra Füger;Petra Füger;Jasmin K Hefendehl;Jasmin K Hefendehl;Karthik Veeraraghavalu;Ann-Christin Wendeln;Ann-Christin Wendeln

  • TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling.

    Brian C. Cooley;Jose Nevado;Jose Nevado;Jason Mellad;Dan Yang

  • Inducible Cre Mice

    Susanne Feil;Nadejda Valtcheva;Robert Feil

  • Cyclic GMP-Dependent Protein Kinases and the Cardiovascular System Insights From Genetically Modified Mice

    Robert Feil;Suzanne M. Lohmann;Hugo de Jonge;Ulrich Walter

  • Dominant role of smooth muscle L-type calcium channel Cav1.2 for blood pressure regulation.

    Sven Moosmang;Verena Schulla;Andrea Welling;Robert Feil

  • Functional embryonic cardiomyocytes after disruption of the L-type alpha1C (Cav1.2) calcium channel gene in the mouse.

    Claudia Seisenberger;Verena Specht;Andrea Welling;Josef Platzer

  • Physiology and Pathophysiology of Vascular Signaling Controlled by Cyclic Guanosine 3′,5′-Cyclic Monophosphate–Dependent Protein Kinase

    Thomas Münzel;Robert Feil;Alexander Mülsch;Suzanne M. Lohmann

  • Platelet-derived HMGB1 is a critical mediator of thrombosis.

    Sebastian Vogel;Sebastian Vogel;Rebecca Bodenstein;Qiwei Chen;Susanne Feil

  • A stimulatory role for cGMP-dependent protein kinase in platelet activation.

    Zhenyu Li;Xiaodong Xi;Minyi Gu;Robert Feil

  • Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice.

    Verena Schulla;Erik Renström;Robert Feil;Susanne Feil

  • Elevated Blood Pressure Linked to Primary Hyperaldosteronism and Impaired Vasodilation in BK Channel–Deficient Mice

    Matthias Sausbier;Claudia Arntz;Iancu Bucurenciu;Hong Zhao

  • Regulation of cGMP-specific phosphodiesterase (PDE5) phosphorylation in smooth muscle cells

    Sergei D. Rybalkin;Irina G. Rybalkina;Robert Feil;Franz Hofmann

Frequent Co-Authors

Franz Hofmann
Franz Hofmann Technical University of Munich
Peter Ruth
Peter Ruth University of Tübingen
Fritz G. Rathjen
Fritz G. Rathjen Max Delbrück Center for Molecular Medicine
Laurinda A. Jaffe
Laurinda A. Jaffe University of Connecticut Health Center
Urs Albrecht
Urs Albrecht University of Fribourg
Lukas Rüttiger
Lukas Rüttiger University of Tübingen
Viacheslav O. Nikolaev
Viacheslav O. Nikolaev Universität Hamburg
Marlies Knipper
Marlies Knipper University of Tübingen
Martin Biel
Martin Biel Ludwig-Maximilians-Universität München
Meinrad Gawaz
Meinrad Gawaz University of Tübingen

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