World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
10280
World Ranking
17948
National Ranking
1235

Overview

Roland K. Hartmann is affiliated with Philipp University of Marburg in Germany and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology. Their research encompasses multiple subfields including Molecular Biology, Infectious Diseases, Genetics, Ecology, and Plant Science.

The scientist has authored numerous papers, focusing particularly on mechanisms involving RNA and protein synthesis, bacterial genetics and biotechnology, RNA modifications and cancer, bacterial-phage interactions, viral infections, genomics, and RNA splicing. Hartmann's frequent coauthors include Arnold Grünweller, Marcus Lechner, Wiebke Obermann, John Ziebuhr, and Markus Gößringer.

Their frequent publication venues reveal a preference for journals specializing in RNA and molecular biology, including the following:

  • RNA
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • RNA Biology
  • Antiviral Research

Some of the recent papers authored or co-authored by Roland K. Hartmann illustrate the trajectory of their research interests. These works include:

  • Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (−) and the eIF4A-inhibitor Silvestrol, 2020, published in Antiviral Research
  • The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo, 2021, published in Antiviral Research
  • Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates-A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics, 2021, published in Microorganisms
  • Structure and mechanistic features of the prokaryotic minimal RNase P, 2021, published in eLife
  • Cleavage kinetics of human mitochondrial RNase P and contribution of its non-nuclease subunits, 2023, published in Nucleic Acids Research

Hartmann's main research topics can be grouped as follows:

  • RNA and protein synthesis mechanisms
  • Bacterial Genetics and Biotechnology
  • RNA modifications and cancer
  • Bacteriophages and microbial interactions
  • Viral Infections and Outbreaks Research
  • Genomics and Phylogenetic Studies
  • RNA Research and Splicing

This body of work reflects a consistent focus on understanding RNA-related mechanisms and their applications in biology and disease research. The scientist's collaborations and choices of publication venues show an active engagement with contemporary molecular biology discourse.

Best Publications

  • Diverse Applications of Nanomedicine

    Beatriz Pelaz;Christoph Alexiou;Ramon A. Alvarez-Puebla;Frauke Alves;Frauke Alves

  • tRNAdb 2009: compilation of tRNA sequences and tRNA genes

    Frank Jühling;Mario Mörl;Roland K. Hartmann;Mathias Sprinzl

  • MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma

    Ahmed Fawzy Ibrahim;Ulrike Weirauch;Maren Thomas;Arnold Grünweller

  • Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites

    Andreas H. Ratje;Andreas H. Ratje;Justus Loerke;Aleksandra Mikolajka;Matthias Brünner

  • A single Arabidopsis organellar protein has RNase P activity.

    Anthony Gobert;Bernard Gutmann;Andreas Taschner;Markus Gößringer

  • Locked nucleic acid oligonucleotides: the next generation of antisense agents?

    Arnold Grünweller;Roland K Hartmann

  • Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses.

    Christin Müller;Falk W. Schulte;Kerstin Lange-Grünweller;Wiebke Obermann

  • The enigma of ribonuclease P evolution.

    Enno Hartmann;Roland K Hartmann

  • The making of tRNAs and more - RNase P and tRNase Z.

    Roland K Hartmann;Markus Gössringer;Bettina Späth;Susan Fischer

  • Ribonuclease P (RNase P) RNA is converted to a Cd(2+)-ribozyme by a single Rp-phosphorothioate modification in the precursor tRNA at the RNase P cleavage site.

    Jens M. Warnecke;Jens Peter Furste;Wolf-Dietrich Hardt;Volker A. Erdmann

  • Orthology detection combining clustering and synteny for very large datasets.

    Marcus Lechner;Maribel Hernandez-Rosales;Daniel Doerr;Nicolas Wieseke

  • The proto-oncogene Pim-1 is a target of miR-33a

    M Thomas;K Lange-Grünweller;U Weirauch;D Gutsch

  • Handbook of RNA biochemistry

    Roland K. Hartmann

  • Tissue-specific genes code for polypeptide VIa of bovine liver and heart cytochrome c oxidase

    B. Kadenbach;R. Hartmann;R. Glanville;G. Buse

  • Role of metal ions in the hydrolysis reaction catalyzed by RNase P RNA from Bacillus subtilis.

    Jens M Warnecke;Rita Held;Silke Busch;Roland K Hartmann

  • Polymer-related off-target effects in non-viral siRNA delivery.

    Olivia M. Merkel;Andrea Beyerle;Benedikt M. Beckmann;Mengyao Zheng

  • Functional role and therapeutic potential of the pim-1 kinase in colon carcinoma.

    Ulrike Weirauch;Ulrike Weirauch;Nadine Beckmann;Nadine Beckmann;Maren Thomas;Arnold Grünweller

  • Lead‐ion‐induced cleavage of RNase P RNA

    Jerzy Ciesiolka;Wolf-Dietrich Hardt;Judith Schlegl;Volker A. Erdmann

  • Rp-phosphorothioate modifications in RNase P RNA that interfere with tRNA binding.

    W.D. Hardt;J.M. Warnecke;V.A. Erdmann;R.K. Hartmann

  • tRNAdb 2009: compilation of tRNA sequences and tRNA genes

    Frank Jühling;Mario Mörl;Roland K Hartmann;Peter Stadler

Frequent Co-Authors

Volker A. Erdmann
Volker A. Erdmann Freie Universität Berlin
John Ziebuhr
John Ziebuhr University of Giessen
Achim Aigner
Achim Aigner Leipzig University
Stephan Becker
Stephan Becker Philipp University of Marburg
Gabriele Klug
Gabriele Klug University of Giessen
Stephan Pleschka
Stephan Pleschka University of Giessen
Peter F. Stadler
Peter F. Stadler Leipzig University
Andre G. Skirtach
Andre G. Skirtach Ghent University
Maurizio Prato
Maurizio Prato University of Trieste

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