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Tetsuro Hirose

Tetsuro Hirose

D-Index & Metrics

Molecular Biology

D-Index
61
Citations
16496
World Ranking
1892
National Ranking
154

Overview

Tetsuro Hirose is affiliated with Osaka University in Japan, specializing in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research output encompasses a significant focus on Molecular Biology, Cancer Research, and Surgery, with additional interests in Pulmonary and Respiratory Medicine and Genetics.

The scientist's research topics include:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • RNA and protein synthesis mechanisms
  • RNA regulation and disease
  • Gastrointestinal disorders and treatments
  • Genetic Neurodegenerative Diseases

They have co-authored frequently with several researchers, including:

  • Shinichi Nakagawa
  • Tomohiro Yamazaki
  • Kensuke Ninomiya
  • Tetsuya Yamamoto
  • Kazuhiko Kitaguchi

Key venues where Tetsuro Hirose has published multiple times include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
  • The EMBO Journal
  • Suizo
  • Nature Reviews Molecular Cell Biology

Notable recent papers authored or co-authored by Tetsuro Hirose are:

  • "A guide to membraneless organelles and their various roles in gene regulation" (2022, Nature Reviews Molecular Cell Biology)
  • "Long non-coding RNAs: definitions, functions, challenges and recommendations" (2023, Nature Reviews Molecular Cell Biology) - authored by John S. Mattick but relevant to their field
  • "Functional annotation of human long noncoding RNAs via molecular phenotyping" (2020, Genome Research)
  • "NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis" (2021, Cell Metabolism)
  • "Paraspeckles are constructed as block copolymer micelles" (2021, The EMBO Journal)

Their research emphasizes the molecular mechanisms of RNA, with significant contributions to understanding long non-coding RNAs and subcellular structures such as membraneless organelles and paraspeckles. Cancer-related molecular pathways, especially those involving RNA modifications, are central to their investigations.

Best Publications

  • MENε/β noncoding RNAs are essential for structural integrity of nuclear paraspeckles

    Yasnory T. F. Sasaki;Takashi Ideue;Miho Sano;Toutai Mituyama

  • The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer

    Dimple Chakravarty;Andrea Sboner;Sujit S. Nair;Eugenia Giannopoulou

  • Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation.

    Tomohiro Yamazaki;Sylvie Souquere;Takeshi Chujo;Simon Kobelke

  • NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

    Tetsuro Hirose;Giorgio Virnicchi;Akie Tanigawa;Takao Naganuma

  • p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity

    Carmen Adriaens;Laura Standaert;Jasmine Barra;Mathilde Latil

  • Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspeckles.

    Takao Naganuma;Shinichi Nakagawa;Akie Tanigawa;Yasnory F Sasaki

  • Paraspeckles: Where Long Noncoding RNA Meets Phase Separation.

    Archa H. Fox;Archa H. Fox;Shinichi Nakagawa;Tetsuro Hirose;Charles S. Bond

  • Malat1 is not an essential component of nuclear speckles in mice.

    Shinichi Nakagawa;Joanna Y. Ip;Go Shioi;Vidisha Tripathi

  • Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization

    Jason A. West;Mari Mito;Satoshi Kurosaka;Toru Takumi

  • Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles

    Sven Hennig;Sven Hennig;Geraldine Kong;Taro Mannen;Agata Sadowska

  • Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice.

    Shinichi Nakagawa;Takao Naganuma;Go Shioi;Tetsuro Hirose

  • The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis

    Yoshinori Nishimoto;Shinichi Nakagawa;Tetsuro Hirose;Hirotaka James Okano;Hirotaka James Okano

  • EVOLUTION AND MECHANISM OF TRANSLATION IN CHLOROPLASTS

    Masahiro Sugiura;Tetsuro Hirose;Mamoru Sugita

  • The lncRNA Neat1 is required for corpus luteum formation and the establishment of pregnancy in a subpopulation of mice.

    Shinichi Nakagawa;Masayuki Shimada;Kaori Yanaka;Mari Mito

  • Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles

    Ryu Miyagawa;Keiko Tano;R. I.E. Mizuno;Y. O. Nakamura

  • Paraspeckle formation during the biogenesis of long non-coding RNAs.

    Takao Naganuma;Tetsuro Hirose

  • Involvement of a site-specific trans-acting factor and a common RNA-binding protein in the editing of chloroplast mRNAs: development of a chloroplast in vitro RNA editing system.

    Tetsuro Hirose;Masahiro Sugiura;Masahiro Sugiura

  • Cis-acting elements and trans-acting factors for accurate translation of chloroplast psbA mRNAs: development of an in vitro translation system from tobacco chloroplasts.

    T Hirose;M Sugiura

  • Both RNA editing and RNA cleavage are required for translation of tobacco chloroplast ndhD mRNA : a possible regulatory mechanism for the expression of a chloroplast operon consisting of functionally unrelated genes

    Tetsuro Hirose;Masahiro Sugiura

  • Neat1 is a p53-inducible lincRNA essential for transformation suppression.

    Stephano S. Mello;Carolyn Sinow;Nitin Raj;Pawel K. Mazur

Frequent Co-Authors

Shinichi Nakagawa
Shinichi Nakagawa University of New South Wales
Masahiro Sugiura
Masahiro Sugiura Nagoya University
Mamoru Sugita
Mamoru Sugita Nagoya University
Kiyoshi Asai
Kiyoshi Asai University of Tokyo
Akila Mayeda
Akila Mayeda Fujita Health University
Charles S. Bond
Charles S. Bond University of Western Australia
Gérard Pierron
Gérard Pierron Centre national de la recherche scientifique, CNRS

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