World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
45
Citations
11151
World Ranking
2839
National Ranking
211

Overview

Akila Mayeda is affiliated with Fujita Health University in Japan and works primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their research expertise includes Molecular Biology, Oncology, Cancer Research, Pulmonary and Respiratory Medicine, and Infectious Diseases.

The scientist's research covers topics such as RNA modifications and cancer, RNA research and splicing, RNA and protein synthesis mechanisms, microRNA in disease regulation, cancer immunotherapy and biomarkers, lung cancer treatments and mutations, and circular RNAs in diseases.

Recent publications by Akila Mayeda include the following:

  • Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats, 2020, iScience
  • SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns, 2021, Nature Communications
  • Novel LAMC2 fusion protein has tumor-promoting properties in ovarian carcinoma, 2021, Cancer Science
  • Spliceostatin A interaction with SF3B limits U1 snRNP availability and causes premature cleavage and polyadenylation, 2021, Cell chemical biology
  • The Exon Junction Complex Core Represses Cancer-Specific Mature mRNA Re-splicing: A Potential Key Role in Terminating Splicing, 2021, International Journal of Molecular Sciences

Frequent coauthors collaborating with Akila Mayeda include:

  • Kazuhiro Fukumura
  • Rei Yoshimoto
  • Ken-ichi Fujita
  • Luca Sperotto
  • Hyun-Seo Kang

The scientist's work has been published repeatedly in the following venues:

  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • iScience
  • Nature Communications
  • Research Square (Research Square)

Best Publications

  • Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2

    Akila Mayeda;Adrian R. Krainer

  • Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

    Adrian R. Krainer;Akila Mayeda;Diane Kozak;Georgia Binns

  • Characterization of RNase R-digested cellular RNA source that consists of lariat and circular RNAs from pre-mRNA splicing

    Hitoshi Suzuki;Yuhong Zuo;Jinhua Wang;Michael Q. Zhang

  • Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins.

    Jun Zhu;Akila Mayeda;Adrian R. Krainer

  • Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.

    A Hanamura;J F Cáceres;A Mayeda;B R Franza

  • Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins.

    Akila Mayeda;Stephen H. Munroe;Javier F. Cáceres;Adrian R. Krainer

  • General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer.

    Qiang Sun;A. Mayeda;R. K. Hampson;A. R. Krainer

  • hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing.

    Massimo Caputi;Akila Mayeda;Adrian R. Krainer;Alan M. Zahler

  • Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.

    Gavin R. Screaton;Javier F. Cáceres;Akila Mayeda;Martyn V. Bell

  • Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF.

    Akila Mayeda;D. M. Helfman;A. R. Krainer

  • General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection.

    Xiang-Dong Fu;Akila Mayeda;Tom Maniatis;Adrian R. Krainer

  • Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF

    I.C. Eperon;D.C. Ireland;R.A. Smith;A. Mayeda

  • Selection of alternative 5' splice sites: role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1.

    Ian C. Eperon;Olga V. Makarova;Akila Mayeda;Akila Mayeda;Stephen H. Munroe

  • MALAT1 long non-coding RNA in cancer

    Rei Yoshimoto;Akila Mayeda;Minoru Yoshida;Shinichi Nakagawa

  • Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles

    Ryu Miyagawa;Keiko Tano;R. I.E. Mizuno;Y. O. Nakamura

  • Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors

    Raymond T. O'Keefe;Akila Mayeda;Cynthia L. Sadowski;Adrian R. Krainer

  • Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements.

    Akila Mayeda;Gavin R. Screaton;Sharon D. Chandler;Xiang Dong Fu

  • Purification and characterization of human RNPS1: a general activator of pre‐mRNA splicing

    Akila Mayeda;Joseph Badolato;Joseph Badolato;Ryuji Kobayashi;Michael Q. Zhang

  • The Subcellular Localization of SF2/ASF Is Regulated by Direct Interaction with SR Protein Kinases (SRPKs)

    Jun Koizumi;Yoshichika Okamoto;Hiroshi Onogi;Akila Mayeda

  • RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins.

    Sharon D. Chandler;Akila Mayeda;Joanne M. Yeakley;Adrian R. Krainer

Frequent Co-Authors

Adrian R. Krainer
Adrian R. Krainer Cold Spring Harbor Laboratory
Tetsuro Hirose
Tetsuro Hirose Osaka University
Jørgen Kjems
Jørgen Kjems Aarhus University
Javier F. Cáceres
Javier F. Cáceres University of Edinburgh
Kazunori Imaizumi
Kazunori Imaizumi Hiroshima University
Masaya Tohyama
Masaya Tohyama Kindai University
Taiichi Katayama
Taiichi Katayama Osaka University
Gavin R. Screaton
Gavin R. Screaton University of Oxford
Kinji Ohno
Kinji Ohno Nagoya University
Michael Q. Zhang
Michael Q. Zhang The University of Texas at Dallas

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