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2025
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Molecular Biology
USA
2026

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Best Female Scientists

D-Index
135
Citations
69976
World Ranking
282
National Ranking
175

Molecular Biology

D-Index
134
Citations
69479
World Ranking
158
National Ranking
101

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award

Overview

Joan A. Steitz is affiliated with Yale University in the United States and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology. Their research predominantly focuses on Molecular Biology, specifically RNA and protein synthesis mechanisms, RNA research and splicing, and RNA modifications related to cancer. Additional research interests include Genomics and Chromatin Dynamics, Infectious Diseases, and Cancer Research.

Steitz's recent publications demonstrate engagement with various molecular and infectious disease topics. Notable papers include:

  • "Hyperosmotic stress alters the RNA polymerase II interactome and induces readthrough transcription despite widespread transcriptional repression," 2021, published in Molecular Cell
  • "SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes," 2021, Proceedings of the National Academy of Sciences
  • "Who let the DoGs out? - biogenesis of stress-induced readthrough transcripts," 2021, Trends in Biochemical Sciences
  • "RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction," 2021, Science
  • "STL-seq reveals pause-release and termination kinetics for promoter-proximal paused RNA polymerase II transcripts," 2021, Molecular Cell

Frequent co-authors collaborating with Steitz include Nicolle A. Rosa-Mercado, Joshua T. Zimmer, Matthew D. Simon, Seyed-Fakhreddin Torabi, and Suzanne J. DeGregorio. These collaborators have co-authored multiple papers, indicating consistent research partnerships.

The scientist's research has been published in several key venues beyond Molecular Cell and Proceedings of the National Academy of Sciences, such as bioRxiv (Cold Spring Harbor Laboratory), Trends in Biochemical Sciences, and Science. Molecular Cell and Proceedings of the National Academy of Sciences are the most frequent publication venues.

Main research topics covered in Steitz's work include:

  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • SARS-CoV-2 and COVID-19 Research
  • Cancer-related molecular mechanisms research
  • Animal Virus Infections Studies

Best Publications

  • Switching from repression to activation: microRNAs can up-regulate translation.

    Shobha Vasudevan;Yingchun Tong;Joan A. Steitz

  • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

    C.M. Counter;A.A. Avilion;C.E. LeFeuvre;N.G. Stewart

  • The noncoding RNA revolution-trashing old rules to forge new ones.

    Thomas R. Cech;Thomas R. Cech;Joan A. Steitz

  • Are snRNPs involved in splicing

    Michael R. Lerner;John A. Boyle;Stephen M. Mount;Sandra L. Wolin

  • Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR.

    J. Robin Lytle;Therese A. Yario;Joan A. Steitz

  • Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

    Michael Rush Lerner;Joan Argetsinger Steitz

  • A general two-metal-ion mechanism for catalytic RNA

    Thomas A. Steitz;Joan A. Steitz

  • HuR and mRNA stability

    C. M. Brennan;J. A. Steitz

  • OVEREXPRESSION OF HUR, A NUCLEAR-CYTOPLASMIC SHUTTLING PROTEIN, INCREASES THE IN VIVO STABILITY OF ARE-CONTAINING MRNAS

    Xinhao Cynthia Fan;Joan A. Steitz

  • How ribosomes select initiator regions in mRNA: base pair formation between the 3' terminus of 16S rRNA and the mRNA during initiation of protein synthesis in Escherichia coli.

    Joan Argetsinger Steitz;Karen Jakes

  • Identification of a sex-factor-affinity site in E. coli as gamma delta

    M. S. Guyer;R. R. Reed;J. A. Steitz;K. B. Low

  • Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease

    Ethan A. Lerner;Michael R. Lerner;Charles A. Janeway;Joan A. Steitz

  • AU-Rich-Element-Mediated Upregulation of Translation by FXR1 and Argonaute 2

    Shobha Vasudevan;Joan A. Steitz

  • Polypeptide Chain Initiation: Nucleotide Sequences of the Three Ribosomal Binding Sites in Bacteriophage R17 RNA

    Joan Argetsinger Steitz

  • Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus.

    Michael R. Lerner;Nancy C. Andrews;George Miller;Joan A. Steitz

  • U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing

    Douglas L. Black;Benoit Chabot;Joan A. Steitz

  • The U1 small nuclear RNA-protein complex selectively binds a 5' splice site in vitro.

    Stephen M. Mount;Ingvar Pettersson;Monique Hinterberger;Aavo Karmas

  • HNS, a nuclear-cytoplasmic shuttling sequence in HuR

    Xinhao Cynthia Fan;Joan A. Steitz

  • Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon.

    Jens Lykke-Andersen;Mei-Di Shu;Joan A. Steitz

  • 遺伝子の分子生物学 = Molecular biology of the gene

    James Dewey Watson;Nancy Hopkins;Jeffrey W Roberts;Joan Argetsinger Steitz

Frequent Co-Authors

Sandra L. Wolin
Sandra L. Wolin National Cancer Institute
John A. Hardin
John A. Hardin Albert Einstein College of Medicine
Thomas A. Steitz
Thomas A. Steitz Yale University
Tetsuro Hirose
Tetsuro Hirose Osaka University
Benoit Chabot
Benoit Chabot Université de Sherbrooke
Daniel DiMaio
Daniel DiMaio Yale University
Jimin Wang
Jimin Wang Yale University
Erik J. Sontheimer
Erik J. Sontheimer University of Massachusetts Chan Medical School

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