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Biology and Biochemistry

D-Index
49
Citations
8794
World Ranking
18015
National Ranking
7370

Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Eric Wickstrom is affiliated with Thomas Jefferson University in the United States and contributes to the fields of Biochemistry, Genetics, and Molecular Biology. Their research focuses primarily on Molecular Biology and Cancer Research, with significant work relating to RNA modifications and cancer, microRNA in disease regulation, DNA and nucleic acid chemistry, and cancer-related molecular mechanisms research.

They have authored several research papers, including:

  • Interactions of antisense DNA oligonucleotide analogs with phospholipid membranes (liposomes), 2020, UNC Libraries
  • Effect of microRNA-21 blockade in human triple negative breast cancer allografts on progression and immune checkpoint proteins, 2023, Journal of Clinical Oncology
  • IGF1R-Targeted Delivery of a Bridged Nucleic Acid Oligonucleotide-Peptide Conjugate for MicroRNA 21 Inhibition in Triple-Negative Breast Cancer, 2025, bioRxiv (Cold Spring Harbor Laboratory)

Their frequent co-authors include Vilas Desai, Saghir Akhtar, Soumitra Basu, R. L. Juliano, and Yuanyuan Jin.

Their work has appeared in several publication venues, notably UNC Libraries, Journal of Clinical Oncology, and bioRxiv (Cold Spring Harbor Laboratory).

Eric Wickstrom was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2010.

Best Publications

  • A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

    Reino Heikkila;Gisela Schwab;Eric Wickstrom;Shee Loong Loke

  • Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA

    Erica L. Wickstrom;Thomas A. Bacon;Audrey Gonzalez;Dennis L. Freeman

  • Oligodeoxynucleotide stability in subcellular extracts and culture media.

    Thomas A. Bacon;Francois Morvan;Bernard Rayner;Jean-Louis Imbach

  • Oligodeoxynucleoside phosphorothioate stability in subcellular extracts, culture media, sera and cerebrospinal fluid.

    Jeannette M. Campbell;Thomas A. Bacon;Eric Wickstrom

  • The inhibition of Staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection.

    Valentin Antoci;Christopher S. Adams;Javad Parvizi;Helen M. Davidson

  • Vancomycin Covalently Bonded to Titanium Beads Kills Staphylococcus aureus

    Binoy Jose;Valentin Antoci;Allen R. Zeiger;Eric Wickstrom

  • Prospects for antisense nucleic acid therapy of cancer and AIDS

    Eric Wickstrom

  • Interactions of antisense DNa oliginucletide analogs with phospholid membranes (liposomes)

    Saghir akhtar;Soumitra Basu;Eric Wickstrom;R.L. Juliano

  • Vancomycin covalently bonded to titanium alloy prevents bacterial colonization.

    Valentin Antoci;Samuel B. King;Binoy Jose;Javad Parvizi

  • Integrated molecular targeting of IGF1R and HER2 surface receptors and destruction of breast cancer cells using single wall carbon nanotubes

    Ning Shao;Shaoxin Lu;Eric Wickstrom;Balaji Panchapakesan

  • Synthesis and Characterization of a Peptide Nucleic Acid Conjugated to a d-Peptide Analog of Insulin-like Growth Factor 1 for Increased Cellular Uptake

    Soumitra Basu;Eric Wickstrom

  • Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA.

    Marc T. Abrams;Noreen M. Robertson;Kyonggeun Yoon;Eric Wickstrom

  • Transformed and immortalized cellular uptake of oligodeoxynucleoside phosphorothioates, 3′-Alkylamino oligodeoxynucleotides, 2′-o-methyl oligoribonucleotides, oligodeoxynucleoside methylphosphonates, and peptide nucleic acids

    Gary D. Gray;Soumitra Basu;Eric Wickstrom

  • Walking along human c-myc mRNA with antisense oligodeoxynucleotides: maximum efficacy at the 5' cap region.

    Bacon Ta;Wickstrom E

  • Single-wall carbon nanotube nanobomb agents for killing breast cancer cells

    Balaji Panchapakesan;Shaoxin Lu;Kousik Sivakumar;Kasif Taker

  • Antisense c-myc and immunostimulatory oligonucleotide inhibition of tumorigenesis in a murine B-cell lymphoma transplant model.

    Janet B. Smith;Eric Wickstrom

  • Antisense DNA inhibition of tumor growth induced by c-Ha-ras oncogene in nude mice.

    Gary D. Gray;Olga M. Hernandez;Denise Hebel;Malcolm Root

  • Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant IRS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1.

    Gregory Cesarone;Om Prakash Edupuganti;Chang-Po Chen;Eric Wickstrom

  • Nanotube–antibody biosensor arrays for the detection of circulating breast cancer cells

    Ning Shao;Eric Wickstrom;Balaji Panchapakesan;Balaji Panchapakesan

  • PET Imaging of Oncogene Overexpression Using 64Cu-Vasoactive Intestinal Peptide (VIP) Analog: Comparison with 99mTc-VIP Analog

    Mathew L Thakur;Mohan R Aruva;Jean Gariepy;Paul Acton

Frequent Co-Authors

Leonard G. Gomella
Leonard G. Gomella Thomas Jefferson University
Irving M. Shapiro
Irving M. Shapiro Thomas Jefferson University
Norman J. Wagner
Norman J. Wagner University of Delaware
Bo Lu
Bo Lu The Ohio State University
Javad Parvizi
Javad Parvizi Acıbadem Mehmet Ali Aydınlar University
Ulrich Rodeck
Ulrich Rodeck Thomas Jefferson University
Rudy L. Juliano
Rudy L. Juliano University of North Carolina at Chapel Hill
William R. Davidson
William R. Davidson University of Georgia
Paul Ducheyne
Paul Ducheyne University of Pennsylvania
Russell J. Composto
Russell J. Composto University of Pennsylvania

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