Wojciech J. Stec

Research.com Recognitions

• 2007 - Polish Academy of Science
• 2004 - Prize of the Foundation for Polish Science - Nagroda Fundacji na rzecz Nauki Polskiej for obtaining new biologically active compounds with a high treatment potential, using his own innovative method for the synthesis of thiophosphate DNA analogues

Overview

Best Publications

• Inner-orbital binding-energy shifts of antimony and bismuth compounds

  Wayne E. Morgan;Wojciech J. Stec;John R. Van Wazer

  576
  Citations

• Inner-orbital photoelectron spectroscopy of the alkali metal halides, perchlorates, phosphates, and pyrophosphates

  Wayne E. Morgan;John R. Van Wazer;Wojciech J. Stec

  514
  Citations

• Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogs of oligodeoxyribonucleotides

  Wojciech J. Stec;Gerald Zon;William Egan

  486
  Citations

• Cryo-EM structure of the human α1β3γ2 GABA A receptor in a lipid bilayer.

  Laverty D;Desai R;Uchański T;Masiulis S

  342
  Citations

• Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

  Jeremy L. Clark;Laurent Hollecker;J. Christian Mason;Lieven J. Stuyver

  341
  Citations

• Novel route to oligo(deoxyribonucleoside phosphorothioates). Stereocontrolled synthesis of P-chiral oligo(deoxyribonucleoside phosphorothioates)

  Wojciech J. Stec;Andrzej Grajkowski;Maria Koziolkiewicz;Bogdan Uznanski

  254
  Citations

• Competitive cAMP antagonists for cAMP-receptor proteins.

  P J Van Haastert;R Van Driel;B Jastorff;J Baraniak

  246
  Citations

• Phosphorothioate-modified oligodeoxyribonucleotides. III. NMR and UV spectroscopic studies of the Rp-Rp, Sp-Sp, and Rp-Sp duplexes, [d(GGSAATTCC)]2, derived from diastereomeric O-ethyl phosphorothioates.

  L A LaPlanche;T L James;C Powell;W D Wilson

  205
  Citations

• Diastereomers of Nucleoside 3'-O-(2-Thio-1,3,2-oxathia(selena)phospholanes): Building Blocks for Stereocontrolled Synthesis of Oligo(nucleoside phosphorothioate)s

  Wojciech J. Stec;Andrzej Grajkowski;Anna Kobylanska;Boleslaw Karwowski

  192
  Citations

• Deoxyribonucleoside 3‘-O-(2-Thio- and 2-Oxo-“spiro”-4,4-pentamethylene-1,3,2-oxathiaphospholane)s: Monomers for Stereocontrolled Synthesis of Oligo(deoxyribonucleoside phosphorothioate)s and Chimeric PS/PO Oligonucleotides§

  Wojciech J. Stec;Bolesław Karwowski;Małgorzata Boczkowska;Piotr Guga

  185
  Citations

• Reversed-phase high-performance liquid chromatographic separation of diastereomeric phosphorothioate analogues of oligodeoxyribonucleotides and other backbone-modified congeners of dna

  Wojciech J. Stec;Gerald Zon;Bogdan Uznaǹski

  183
  Citations

• Inhibitory action of certain cyclophosphate derivatives of cAMP on cAMP-dependent protein kinases

  René J.W. de Wit;Doeke Hekstra;Bernd Jastorff;Wojciech J. Stec

  181
  Citations

• SURVEY AND SUMMARY Recent advances in the elucidation of the mechanisms of action of ribozymes

  Yasuomi Takagi;Masaki Warashina;Wojciech J. Stec;Koichi Yoshinari

  181
  Citations

• Measured binding energy shifts of "3p" and "3d" electrons in arsenic compounds

  Wojciech J. Stec;Wayne E. Morgan;Royal G. Albridge;John R. Van Wazer

  171
  Citations

• Octa(thymidine methanephosphonates) of partially defined stereochemistry: synthesis and effect of chirality at phosphorus on binding to pentadecadeoxyriboadenylic acid

  Zbigniew J. Lesnikowski;Maria Jaworska;Wojciech J. Stec

  164
  Citations

• Stereocontrolled Synthesis of Oligo(nucleoside phosphorothioate)s

  Wojciech J. Stec;Andrzej Wilk

  163
  Citations

• Interaction of cAMP Derivatives with the ‘Stable’ CAMP-Binding Site in the CAMP-Dependent Protein Kinase Type I

  Renè J. W. de Wit;Jürgen Hoppe;Wojciech J. Stec;Janina Baraniak

  159
  Citations

• Inhibition of glycogenolysis in isolated rat hepatocytes by the Rp diastereomer of adenosine cyclic 3',5'-phosphorothioate.

  J D Rothermel;W J Stec;J Baraniak;B Jastorff

  155
  Citations

• Structure and dynamics of a DNA.RNA hybrid duplex with a chiral phosphorothioate moiety: NMR and molecular dynamics with conventional and time-averaged restraints.

  Carlos Gonzalez;Wojciech Stec;Mark A. Reynolds;Thomas L. James

  154
  Citations

• Stereodifferentiation—the effect of P chirality of oligo (nucleoside phosphorothioates) on the activity of bacterial RNase H

  Maria Koziolkiewicz;Agnieszka Krakowiak;Marek Kwinkowski;Malgorzata Boczkowska

  144
  Citations