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Overview

Leonard G. Gomella is affiliated with Thomas Jefferson University in the United States, where their research contributions primarily focus on various aspects of medicine, with a significant concentration in urology and oncology.

Their recent academic output includes several papers covering topics such as bladder cancer, prostate cancer, and related treatments. Notable publications include:

  • Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial (2020) published in The Lancet Oncology
  • Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019 (2020) published in Journal of Clinical Oncology
  • The addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy (NRG Oncology/RTOG 0534 SPPORT): an international, multicentre, randomised phase 3 trial (2022) published in The Lancet
  • When and How to Use PARP Inhibitors in Prostate Cancer: A Systematic Review of the Literature with an Update on On-Going Trials (2020) published in European Urology Oncology
  • Cellular rewiring in lethal prostate cancer: the architect of drug resistance (2020) published in Nature Reviews Urology

Their scientific collaboration network includes frequent co-authors such as Costas D. Lallas, Edouard J. Trabulsi, James Ryan Mark, Thenappan Chandrasekar, and William Kevin Kelly, indicating active participation in multidisciplinary research teams.

Leonard G. Gomella's body of work appears in several prominent publication venues, demonstrating a broad influence in urological and oncological research. These venues include:

  • Journal of Clinical Oncology
  • The Journal of Urology
  • Urology
  • European Urology
  • International Journal of Radiation Oncology*Biology*Physics

Their research fields encompass medicine at large with specific subfields that highlight expertise in pulmonary and respiratory medicine, surgery, oncology, genetics, and cancer research.

Key research topics centered on their work include:

  • Prostate Cancer Treatment and Research
  • Prostate Cancer Diagnosis and Treatment
  • Bladder and Urothelial Cancer Treatments
  • Urinary and Genital Oncology Studies
  • BRCA gene mutations in cancer
  • Renal cell carcinoma treatment
  • Urological Disorders and Treatments

Best Publications

  • Effect of dutasteride on the risk of prostate cancer.

    Gerald L. Andriole;David G. Bostwick;Otis W. Brawley;Leonard G. Gomella

  • Micro-RNA profiling in kidney and bladder cancers

    Fedra Gottardo;Chang Gong Liu;Manuela Ferracin;George A. Calin

  • MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets.

    Raffaele Baffa;Matteo Fassan;Matteo Fassan;Stefano Volinia;Brian O'Hara

  • Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs

    Eric Londina;Phillipe Lohera;Aristeidis G. Telonis;Kevin Quann

  • Detection of hematogenous micrometastasis in patients with prostate cancer

    J G Moreno;C M Croce;R Fischer;M Monne

  • Dual Roles of PARP-1 Promote Cancer Growth and Progression

    Matthew J. Schiewer;Jonathan F. Goodwin;Sumin Han;J. Chad Brenner

  • A Comparison of Hexaminolevulinate Fluorescence Cystoscopy and White Light Cystoscopy for the Detection of Carcinoma In Situ in Patients With Bladder Cancer: A Phase III, Multicenter Study

    Yves Fradet;H. Barton Grossman;Leonard Gomella;Seth Lerner

  • A Phase III, Multicenter Comparison of Hexaminolevulinate Fluorescence Cystoscopy and White Light Cystoscopy for the Detection of Superficial Papillary Lesions in Patients With Bladder Cancer

    H. Barton Grossman;Leonard Gomella;Yves Fradet;Alvaro Morales

  • The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

    Ankur Sharma;Wen Shuz Yeow;Adam Ertel;Ilsa Coleman

  • CHEMOPREVENTION OF PROSTATE CANCER IN MEN AT HIGH RISK: RATIONALE AND DESIGN OF THE REDUCTION BY DUTASTERIDE OF PROSTATE CANCER EVENTS (REDUCE) TRIAL

    Gerald Andriole;David Bostwick;Otis Brawley;Leonard Gomella

  • Utilization of polymerase chain reaction technology in the detection of solid tumors

    Ganesh V. Raj M.D.;Jose G. Moreno;Leonard G. Gomella

  • Phase II trial of 96-hour paclitaxel plus oral estramustine phosphate in metastatic hormone-refractory prostate cancer.

    Gary R. Hudes;Faith Nathan;Christina Khater;Naomi Haas

  • Inhibition of growth of prostatic cancer cell lines by peptide analogues of insulin-like growth factor 1.

    Zbigniew Pietrzkowski;Grant Mulholland;Leonard Gomella;Bradford A. Jameson

  • Circulating tumor cells predict survival in patients with metastatic prostate cancer.

    Jose G. Moreno;M. Craig Miller;Steve Gross;W. Jeffrey Allard

  • Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial

    Stephen A. Boorjian;Mehrdad Alemozaffar;Badrinath R. Konety;Neal D. Shore

  • Optimization of Initial Prostate Biopsy in Clinical Practice: Sampling, Labeling, and Specimen Processing

    Marc A. Bjurlin;H. Ballentine Carter;Paul Schellhammer;Michael S. Cookson

  • Genomic Classifier Identifies Men With Adverse Pathology After Radical Prostatectomy Who Benefit From Adjuvant Radiation Therapy

    Robert Benjamin Den;Kasra Yousefi;Edouard John Trabulsi;Firas Abdollah

  • Retroperitoneal and pelvic extraperitoneal laparoscopy: an international perspective

    Inderbir S Gill;Ralph V Clayman;David M Albala;Yoshio Aso

  • Prostate carcinoma: assessment of diagnostic criteria for capsular penetration on endorectal coil MR images.

    E K Outwater;R O Petersen;E S Siegelman;L G Gomella

  • Prostate cancer: contrast-enhanced us for detection.

    Ethan J. Halpern;Martin Rosenberg;Leonard G. Gomella

Frequent Co-Authors

Adam P. Dicker
Adam P. Dicker Thomas Jefferson University
Karen E. Knudsen
Karen E. Knudsen Thomas Jefferson University
Renato V. Iozzo
Renato V. Iozzo Thomas Jefferson University
Carlo M. Croce
Carlo M. Croce The Ohio State University
Neal D. Shore
Neal D. Shore Carolina Urologic Research Center
Matteo Fassan
Matteo Fassan University of Padua
Howard M. Sandler
Howard M. Sandler Cedars-Sinai Medical Center
Seth P. Lerner
Seth P. Lerner Baylor College of Medicine
Gerald L. Andriole
Gerald L. Andriole Washington University in St. Louis
Oliver Sartor
Oliver Sartor Tulane University

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