World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
86
Citations
26280
World Ranking
14159
National Ranking
7173

Overview

Karen E. Knudsen is affiliated with Thomas Jefferson University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology.

The main subfields of study include Pulmonary and Respiratory Medicine, Molecular Biology, Oncology, Cancer Research, and Economics and Econometrics. Their research topics focus significantly on Prostate Cancer Treatment and Research, Cancer, Lipids, and Metabolism, Cancer Genomics and Diagnostics, Cancer-related Molecular Pathways, PARP inhibition in cancer therapy, Prostate Cancer Diagnosis and Treatment, as well as Epigenetics and DNA Methylation.

Knudsen's recent papers demonstrate involvement in various aspects of cancer biology and clinical oncology. Notable publications include:

  • Prostate cancer, 2021, Nature Reviews Disease Primers
  • The DNA methylation landscape of advanced prostate cancer, 2020, Nature Genetics
  • Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019, 2020, Journal of Clinical Oncology
  • Targeting the p300/CBP Axis in Lethal Prostate Cancer, 2021, Cancer Discovery
  • The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair, 2021, Nature Communications

Frequent co-authors include Christopher McNair, Matthew J. Schiewer, Ayesha A. Shafi, Johann S. de Bono, and Denisa Bogdan.

Knudsen has published multiple studies in several key journals and venues such as The Prostate, Journal of Clinical Oncology, Clinical Cancer Research, Cancer Research, and UNC Libraries. The counts of publications in these venues are highest for The Prostate and Journal of Clinical Oncology.

Best Publications

  • DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.

    Joaquin Mateo;Suzanne Carreira;Shahneen Sandhu;Susana Miranda

  • Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure.

    Frederick S. vom Saal;Benson T Akingbemi;Scott M Belcher;Linda S. Birnbaum

  • Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

    David A. Quigley;Ha X. Dang;Shuang G. Zhao;Paul Lloyd

  • Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs

    Eric Londina;Phillipe Lohera;Aristeidis G. Telonis;Kevin Quann

  • Tailoring to RB: tumour suppressor status and therapeutic response.

    Erik S. Knudsen;Karen E. Knudsen

  • Cyclin D1: polymorphism, aberrant splicing and cancer risk

    K E Knudsen;J Alan Diehl;C A Haiman;E S Knudsen

  • Dual Roles of PARP-1 Promote Cancer Growth and Progression

    Matthew J. Schiewer;Jonathan F. Goodwin;Sumin Han;J. Chad Brenner

  • AR, the cell cycle, and prostate cancer

    Steven Paul Balk;Karen E. Knudsen

  • Starving the Addiction: New Opportunities for Durable Suppression of AR Signaling in Prostate Cancer

    Karen E. Knudsen;Howard I. Scher

  • An evaluation of evidence for the carcinogenic activity of bisphenol A.

    Ruth A. Keri;Shuk Mei Ho;Patricia A. Hunt;Karen E. Knudsen

  • The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

    Ankur Sharma;Wen Shuz Yeow;Adam Ertel;Ilsa Coleman

  • A hormone-DNA repair circuit governs the response to genotoxic insult

    Jonathan F. Goodwin;Matthew J. Schiewer;Jeffry L. Dean;Randy S. Schrecengost

  • Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer

    Karen E. Knudsen;Trevor M. Penning

  • BRG-1 is required for RB-mediated cell cycle arrest

    Matthew W. Strobeck;Karen E. Knudsen;Anne F. Fribourg;Marc F. DeCristofaro

  • Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer

    Chellappagounder Thangavel;Jeffry L Dean;Adam Ertel;Karen E Knudsen

  • RB-dependent S-phase response to DNA damage.

    Karen E. Knudsen;Dana Booth;Soheil Naderi;Zvjezdana Sever-Chroneos

  • The meaning of p16(ink4a) expression in tumors: functional significance, clinical associations and future developments.

    Agnieszka K. Witkiewicz;Karen E. Knudsen;Adam P. Dicker;Erik S. Knudsen

  • Beyond DNA Repair: DNA-PK Function in Cancer

    Jonathan F. Goodwin;Karen E. Knudsen

  • Multiple G1 Regulatory Elements Control the Androgen-dependent Proliferation of Prostatic Carcinoma Cells

    Karen E. Knudsen;Karen C. Arden;Webster K. Cavenee

  • The role of lineage plasticity in prostate cancer therapy resistance

    Himisha Beltran;Andrew Hruszkewycz;Howard I. Scher;Jeffrey Hildesheim

Frequent Co-Authors

Adam P. Dicker
Adam P. Dicker Thomas Jefferson University
Leonard G. Gomella
Leonard G. Gomella Thomas Jefferson University
Felix Y. Feng
Felix Y. Feng University of California, San Francisco
Scott A. Tomlins
Scott A. Tomlins University of Michigan–Ann Arbor
Arul M. Chinnaiyan
Arul M. Chinnaiyan University of Michigan–Ann Arbor
Johann S. de Bono
Johann S. de Bono Institute of Cancer Research
Mark A. Rubin
Mark A. Rubin University of Bern
Maha Hussain
Maha Hussain Northwestern University
Tapio Visakorpi
Tapio Visakorpi Tampere University
Lisa M. Butler
Lisa M. Butler University of Adelaide

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