D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 62 Citations 15,229 171 World Ranking 6949 National Ranking 3

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Alpha-synuclein, Biochemistry, Alzheimer's disease, Amyloid and Parkinson's disease. His Alpha-synuclein research includes themes of Mutation and Neurodegeneration. In the subject of general Biochemistry, his work in Hydrogen peroxide, Programmed cell death and Protein structure is often linked to Protein quaternary structure, thereby combining diverse domains of study.

His study in Alzheimer's disease is interdisciplinary in nature, drawing from both Neurocognitive and Neuroimaging. His Amyloid research is multidisciplinary, incorporating elements of Neuroblastoma, Pathogenesis and Cell biology. Omar M. A. El-Agnaf has included themes like Dementia with Lewy bodies, Pathological, Cerebrospinal fluid and Immunology in his Parkinson's disease study.

His most cited work include:

  • Diagnosis and management of dementia with Lewy bodies Fourth consensus report of the DLB Consortium (1355 citations)
  • Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease (528 citations)
  • α-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma (463 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Alpha-synuclein, Parkinson's disease, Biochemistry, Disease and Pathology. His Alpha-synuclein research incorporates themes from Blood plasma, Neurodegeneration and Phosphorylation, Cell biology. His Parkinson's disease research integrates issues from Neuroscience and Immunology.

The various areas that Omar M. A. El-Agnaf examines in his Biochemistry study include Toxicity, Pathogenesis and Amyloid. The concepts of his Disease study are interwoven with issues in Neurology, Oncology and Bioinformatics. Dementia with Lewy bodies, Cerebrospinal fluid, Alzheimer's disease and Atrophy are the primary areas of interest in his Pathology study.

He most often published in these fields:

  • Alpha-synuclein (32.16%)
  • Parkinson's disease (28.07%)
  • Biochemistry (25.73%)

What were the highlights of his more recent work (between 2018-2021)?

  • Parkinson's disease (28.07%)
  • Cerebrospinal fluid (18.13%)
  • Alpha-synuclein (32.16%)

In recent papers he was focusing on the following fields of study:

Omar M. A. El-Agnaf spends much of his time researching Parkinson's disease, Cerebrospinal fluid, Alpha-synuclein, Synucleinopathies and Internal medicine. Within one scientific family, he focuses on topics pertaining to Movement disorders under Cerebrospinal fluid, and may sometimes address concerns connected to Gastroenterology and Alzheimer's disease. His Alpha-synuclein study combines topics in areas such as Substantia nigra, Pars compacta, Dementia with Lewy bodies and Neuroscience.

Dementia with Lewy bodies is a primary field of his research addressed under Pathology. His Synucleinopathies study incorporates themes from Biochemistry, Protein secondary structure, Phosphorylation, Antibody and Genetically modified mouse. His Antibody research is multidisciplinary, incorporating perspectives in Biomarker and Disease.

Between 2018 and 2021, his most popular works were:

  • Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases. (25 citations)
  • Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases. (25 citations)
  • Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates (20 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Omar M. A. El-Agnaf focuses on Antibody, Parkinson's disease, Biomarker, Disease and Neuroscience. The Antibody study combines topics in areas such as Dementia with Lewy bodies and Intracellular, Phosphorylation, Cell biology. His research ties Gastroenterology and Parkinson's disease together.

His research in Biomarker intersects with topics in Area under the curve, α synuclein and Pathology. His primary area of study in Disease is in the field of Synuclein. His Neuroscience research is multidisciplinary, relying on both Fibril and Alpha-synuclein.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Diagnosis and management of dementia with Lewy bodies Fourth consensus report of the DLB Consortium

Ian G. McKeith;Bradley F. Boeve;Dennis W. DIckson;Glenda Halliday.
Neurology (2017)

2253 Citations

Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases.

G. Brent Irvine;Omar M. El-Agnaf;Ganesh M. Shankar;Dominic M. Walsh;Dominic M. Walsh.
Molecular Medicine (2008)

625 Citations

α-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma

Omar M. A. El-Agnaf;Sultan A. Salem;Katerina E. Paleologou;Leanne J. Cooper.
The FASEB Journal (2003)

613 Citations

Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease

Omar M. A. El-Agnaf;Sultan A. Salem;Katerina E. Paleologou;Martin D. Curran.
The FASEB Journal (2006)

607 Citations

α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.

Bruno Fauvet;Martial Kamdem Mbefo;Mohamed-Bilal Fares;Carole Desobry.
Journal of Biological Chemistry (2012)

569 Citations

Aggregates from mutant and wild-type α-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of β-sheet and amyloid-like filaments

Omar M.A El-Agnaf;Ross Jakes;Martin D Curran;Derek Middleton;Derek Middleton.
FEBS Letters (1998)

505 Citations

Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease

T. Tokuda;M.M. Qureshi;M.T. Ardah;S. Varghese.
Neurology (2010)

471 Citations

Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson’s disease.

Takahiko Tokuda;Sultan A. Salem;David Allsop;Toshiki Mizuno.
Biochemical and Biophysical Research Communications (2006)

415 Citations

Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

Brit Mollenhauer;Valerie Cullen;Ilana Kahn;Bryan Krastins.
Experimental Neurology (2008)

415 Citations

Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease.

Brian J. Tabner;Stuart Turnbull;Omar M.A. El-Agnaf;David Allsop.
Free Radical Biology and Medicine (2002)

322 Citations

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