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Biology and Biochemistry

D-Index
62
Citations
18631
World Ranking
10593
National Ranking
807

Overview

David Allsop is affiliated with Lancaster University in the United Kingdom and conducts research primarily within the field of Medicine. Their work is strongly focused on Alzheimer's disease and related neurodegenerative conditions, with significant contributions to areas including Physiology, Health, Toxicology and Mutagenesis, Neurology, Molecular Biology, and Biomaterials.

Their research covers a variety of topics such as:

  • Alzheimer's disease research and treatments
  • Cholinesterase and Neurodegenerative Diseases
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Salivary Gland Disorders and Functions
  • Oral microbiology and periodontitis research
  • Trace Elements in Health
  • Heavy Metal Exposure and Toxicity

Notable recent publications by David Allsop include:

  • "Diagnostic Biomarkers for Alzheimer's Disease Using Non-Invasive Specimens," 2020, Journal of Clinical Medicine
  • "Variation in the concentration and regional distribution of magnetic nanoparticles in human brains, with and without Alzheimer's disease, from the UK," 2021, Scientific Reports
  • "Amyotrophic lateral sclerosis: Correlations between fluid biomarkers of NfL, TDP-43, and tau, and clinical characteristics," 2021, PLoS ONE
  • "Oxidative Stress, Cytotoxic and Inflammatory Effects of Urban Ultrafine Road-Deposited Dust from the UK and Mexico in Human Epithelial Lung (Calu-3) Cells," 2022, Antioxidants
  • "A novel peptide-based tau aggregation inhibitor as a potential therapeutic for Alzheimer's disease and other tauopathies," 2024, Alzheimer's & Dementia

Frequent collaborators include Takashi Kasai, Takuma Ohmichi, Harutsugu Tatebe, Fukiko Kitani-Morii, and Makiko Shinomoto, each having coauthored multiple works with Allsop.

David Allsop's work has appeared in several key scientific journals, notably:

  • Scientific Reports
  • Journal of Clinical Medicine
  • PLoS ONE
  • Antioxidants
  • Alzheimer's & Dementia

Best Publications

  • Amyloid deposition as the central event in the aetiology of Alzheimer's disease

    John Hardy;David Allsop

  • Magnetite pollution nanoparticles in the human brain.

    Barbara A. Maher;Imad A. M. Ahmed;Vassil Karloukovski;Donald A. MacLaren

  • Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

    Tobias Hartmann;Sophie C. Bieger;Babara Brühl;Pentti J. Tienari

  • Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease

    Omar M. A. El-Agnaf;Sultan A. Salem;Katerina E. Paleologou;Martin D. Curran

  • The occult aftermath of boxing.

    G W Roberts;D Allsop;C Bruton

  • α-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma

    Omar M. A. El-Agnaf;Sultan A. Salem;Katerina E. Paleologou;Leanne J. Cooper

  • Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson’s disease.

    Takahiko Tokuda;Sultan A. Salem;David Allsop;Toshiki Mizuno

  • High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

    Hiroaki Fukumoto;Takahiko Tokuda;Takashi Kasai;Noriko Ishigami

  • Inflammatory mechanisms in Alzheimer's disease

    P. Eikelenboom;Shan-Shan Zhan;W. A. Van Gool;D. Allsop

  • Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease.

    Brian J. Tabner;Stuart Turnbull;Omar M.A. El-Agnaf;David Allsop

  • Hydrogen Peroxide Is Generated during the Very Early Stages of Aggregation of the Amyloid Peptides Implicated in Alzheimer Disease and Familial British Dementia

    Brian J. Tabner;Omar M.A. El-Agnaf;Omar M.A. El-Agnaf;Stuart Turnbull;Matthew J. German

  • Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease and down syndrome.

    Harutsugu Tatebe;Takashi Kasai;Takuma Ohmichi;Yusuke Kishi

  • Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis.

    Takashi Kasai;Takahiko Tokuda;Noriko Ishigami;Hiroshi Sasayama

  • Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

    Penelope G. Foulds;J. Douglas Mitchell;Angela Parker;Roisin Turner

  • Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases.

    Brian J. Tabner;Stuart Turnbull;Omar M.A. El-Agnaf;David Allsop

  • Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies

    Katerina E Paleologou;Christine L Kragh;David M A Mann;Sultan A Salem

  • α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro.

    Stuart Turnbull;Brian J Tabner;Omar M.A El-Agnaf;Susan Moore

  • A strategy for designing inhibitors of α -synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders

    Omar M. A. El-Agnaf;Katerina E. Paleologou;Brett Greer;Abdulmawala M. Abogrein

  • Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

    D. Allsop;M. Landon;M. Kidd;J.S. Lowe

  • TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration.

    Penelope Foulds;Erica McAuley;Linda Gibbons;Yvonne Davidson

Frequent Co-Authors

Omar M. A. El-Agnaf
Omar M. A. El-Agnaf Hamad bin Khalifa University
David M. A. Mann
David M. A. Mann University of Manchester
Dominic M. Walsh
Dominic M. Walsh Brigham and Women's Hospital
Francis Martin
Francis Martin University of Lorraine
Konrad Beyreuther
Konrad Beyreuther Heidelberg University
Tobias Hartmann
Tobias Hartmann Saarland University
Stefan F. Lichtenthaler
Stefan F. Lichtenthaler German Center for Neurodegenerative Diseases
Genevieve Evin
Genevieve Evin University of Melbourne
Masato Hasegawa
Masato Hasegawa Tokyo Metropolitan Institute of Medical Science
Julie S. Snowden
Julie S. Snowden University of Manchester

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