What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Alzheimer's disease
His primary scientific interests are in Pathology, Frontotemporal lobar degeneration, Frontotemporal dementia, Alzheimer's disease and Dementia.
His studies in Pathology integrate themes in fields like Cerebral cortex and Down syndrome.
His Frontotemporal lobar degeneration study combines topics in areas such as Genetics, White matter, Subependymal zone, Charged multivesicular body protein 2B and Cytoplasmic inclusion.
The Frontotemporal dementia study combines topics in areas such as Progressive supranuclear palsy and Corticobasal degeneration.
His Alzheimer's disease research includes elements of Molecular biology, Apolipoprotein E and Degenerative disease.
His study in Dementia is interdisciplinary in nature, drawing from both Psychiatry, Cognition, Neuroscience and Amyotrophic lateral sclerosis.
His most cited work include:
- A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD (2859 citations)
- Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 (2839 citations)
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (2556 citations)
What are the main themes of his work throughout his whole career to date?
David M. A. Mann mainly focuses on Pathology, Frontotemporal lobar degeneration, Alzheimer's disease, Disease and Frontotemporal dementia.
Pathology is represented through his Dementia, Neuropathology, C9orf72, Senile plaques and Pathological research.
His Dementia study combines topics from a wide range of disciplines, such as Tau protein, Neuroscience and Cohort study.
His research integrates issues of Cytoplasmic inclusion, Amyotrophic lateral sclerosis, Motor neurone disease and Immunostaining in his study of Frontotemporal lobar degeneration.
His research in Alzheimer's disease intersects with topics in Apolipoprotein E, Amyloid, Endocrinology and Degenerative disease.
His studies deal with areas such as Progressive supranuclear palsy, Genetics and Psychiatry, Aphasia as well as Frontotemporal dementia.
He most often published in these fields:
- Pathology (51.90%)
- Frontotemporal lobar degeneration (28.80%)
- Alzheimer's disease (25.27%)
What were the highlights of his more recent work (between 2014-2021)?
- Pathology (51.90%)
- Frontotemporal lobar degeneration (28.80%)
- Disease (23.37%)
In recent papers he was focusing on the following fields of study:
David M. A. Mann spends much of his time researching Pathology, Frontotemporal lobar degeneration, Disease, Frontotemporal dementia and C9orf72.
He interconnects Dentate gyrus and Temporal cortex in the investigation of issues within Pathology.
His research in Frontotemporal lobar degeneration tackles topics such as Cerebellum which are related to areas like Hippocampal formation.
David M. A. Mann has researched Disease in several fields, including Odds ratio, Differential diagnosis and Cohort.
His Frontotemporal dementia research integrates issues from Progressive supranuclear palsy, Psychiatry, Aphasia and Amyotrophic lateral sclerosis.
The concepts of his C9orf72 study are interwoven with issues in C9orf72 Protein and DNA Repeat Expansion.
Between 2014 and 2021, his most popular works were:
- Magnetite pollution nanoparticles in the human brain. (381 citations)
- Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy (225 citations)
- Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study (105 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Alzheimer's disease
David M. A. Mann focuses on Pathology, Frontotemporal lobar degeneration, Frontotemporal dementia, Disease and Alzheimer's disease.
C9orf72 is the focus of his Pathology research.
David M. A. Mann combines subjects such as Progressive supranuclear palsy, Psychiatry, Cognition, Amyotrophic lateral sclerosis and Tauopathy with his study of Frontotemporal dementia.
His Amyotrophic lateral sclerosis research incorporates elements of Genetics and Aphasia.
His Disease research includes themes of Differential diagnosis, Genome-wide association study and Odds ratio.
His Internal medicine research is multidisciplinary, relying on both Oncology and Gene mutation.
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