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D-Index
88
Citations
33896
World Ranking
13019
National Ranking
6654

Overview

Leslie J. Crofford is affiliated with Vanderbilt University Medical Center in the United States. Their research primarily focuses on the field of Medicine, with notable contributions across several subfields including Psychiatry and Mental Health, Pharmacology, Immunology, Rheumatology, and Epidemiology.

The main topics covered in Crofford's work include:

  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Musculoskeletal pain and rehabilitation
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Inflammatory Myopathies and Dermatomyositis
  • Systemic Sclerosis and Related Diseases
  • Pain Mechanisms and Treatments
  • Osteoarthritis Treatment and Mechanisms

Among the frequent coauthors collaborating with Crofford are Kathleen A. Sluka, Carol Vance, Dana L. Dailey, Ruth L. Chimenti, and Emine O. Bayman, indicating a network of active partnerships in related research domains.

Crofford has published extensively in several venues, including:

  • Journal of Pain
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of the Rheumatic Diseases
  • Arthritis Care & Research
  • Nature Reviews Rheumatology

Representative recent papers authored or coauthored by Crofford include:

  • Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage, 2021, Nature Biomedical Engineering
  • Emotion regulation and the salience network: a hypothetical integrative model of fibromyalgia, 2022, Nature Reviews Rheumatology
  • Using TENS for Pain Control: Update on the State of the Evidence, 2022, Medicina
  • Machine learning predicts stem cell transplant response in severe scleroderma, 2020, Annals of the Rheumatic Diseases
  • Recent Advances in Clinical Translation of Intra-Articular Osteoarthritis Drug Delivery Systems, 2020, Advanced Therapeutics

The research contributions span topics related to pain management, autoimmune and inflammatory diseases, and advanced therapeutic delivery systems, reflecting a multifaceted approach to clinical and translational medicine.

Best Publications

  • Cyclooxygenase in biology and disease

    Raymond N. Dubois;Steven B. Abramson;Leslie Crofford;Rajnish A. Gupta

  • Management of Fibromyalgia Syndrome

    Don L. Goldenberg;Carol Burckhardt;Leslie Crofford

  • COX-1 and COX-2 tissue expression: implications and predictions.

    Crofford Lj

  • Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.

    Leslie J. Crofford;Ronald L. Wilder;Ari P. Ristimaki;Hajime Sano

  • Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial.

    Leslie J. Crofford;Michael C. Rowbotham;Philip J. Mease;I. Jon Russell

  • A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder.

    Lesley M. Arnold;Yili Lu;Leslie J. Crofford;Madelaine Wohlreich

  • Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin‐1: a potential mechanism for inflammatory angiogenesis

    Pazit Ben-Av;Leslie J. Crofford;Ronald L. Wilder;Timothy Hla

  • Hypothalamic-pituitary-adrenal axis perturbations in patients with fibromyalgia.

    Leslie J. Crofford;Stanley R. Pillemer;Konstantine T. Kalogeras;Joseph M. Cash

  • Use of NSAIDs in treating patients with arthritis.

    Leslie J Crofford

  • Patient Perspectives on the Impact of Fibromyalgia

    Lesley M. Arnold;Leslie J. Crofford;Philip J. Mease;Somali Misra Burgess

  • Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.

    K. M. Sullivan;E. A. Goldmuntz;L. Keyes-Elstein;P. A. McSweeney

  • Chronic widespread pain and fibromyalgia: what we know, and what we need to know

    Daniel J. Clauw;Leslie J. Crofford

  • Cognitive function in fibromyalgia patients

    Denise C. Park;Jennifer M. Glass;Meredith Minear;Leslie J. Crofford

  • Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.

    Jerome Wilborn;Leslie J. Crofford;Marie D. Burdick;Steven L. Kunkel

  • In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis.

    H Sano;T Hla;J A Maier;L J Crofford

  • Basic biology and clinical application of specific cyclooxygenase-2 inhibitors

    Leslie J. Crofford;Peter E. Lipsky;Peter Brooks;Steven B. Abramson

  • Involvement of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes.

    Leslie J. Crofford;Bing Tan;Conor J. McCarthy;Timothy Hla

  • Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells.

    Dirk O. Stichtenoth;Staffan Thorén;Huimin Bian;Marc Peters-Golden

  • Fibromyalgia relapse evaluation and efficacy for durability of meaningful relief (FREEDOM): A 6-month, double-blind, placebo-controlled trial with pregabalin

    Leslie J. Crofford;Philip J. Mease;Susan L. Simpson;James P. Young

  • Circadian Relationships between Interleukin (IL)-6 and Hypothalamic-Pituitary-Adrenal Axis Hormones: Failure of IL-6 to Cause Sustained Hypercortisolism in Patients with Early Untreated Rheumatoid Arthritis

    Leslie J. Crofford;Konstantine T. Kalogeras;George Mastorakos;Maria-Alexandra Magiakou

Frequent Co-Authors

Ronald L. Wilder
Ronald L. Wilder National Institutes of Health
Richard A. Nash
Richard A. Nash Fred Hutchinson Cancer Research Center
Elaine F. Remmers
Elaine F. Remmers National Institutes of Health
Keith M. Sullivan
Keith M. Sullivan Duke University
Daniel E. Furst
Daniel E. Furst University of California, Los Angeles
Kathleen A. Sluka
Kathleen A. Sluka University of Iowa
Daniel J. Clauw
Daniel J. Clauw University of Michigan–Ann Arbor
Maureen D. Mayes
Maureen D. Mayes The University of Texas at Austin
Suzanne C. Segerstrom
Suzanne C. Segerstrom University of Kentucky
David A. Williams
David A. Williams Boston Children's Hospital

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