2026 Masato Hasegawa: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	104	1242	1110	70	62	371	44973

Research.com Recognitions

2026 - Research.com Biology and Biochemistry in Japan Leader Award
2025 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Masato Hasegawa is affiliated with the Tokyo Metropolitan Institute of Medical Science in Japan. Their research primarily focuses on the fields of Medicine and Neuroscience, with significant contributions to subfields such as Neurology, Physiology, Molecular Biology, Cellular and Molecular Neuroscience, and Psychiatry and Mental Health.

Their scholarly work addresses several main topics, including:

Alzheimer's disease research and treatments
Parkinson's Disease Mechanisms and Treatments
Neurological diseases and metabolism
Amyotrophic Lateral Sclerosis Research
Prion Diseases and Protein Misfolding
Neurological disorders and treatments
Dementia and Cognitive Impairment Research

Masato Hasegawa has published numerous papers in notable scientific venues. Frequent publication outlets include:

Neuropathology (18 publications)
bioRxiv (Cold Spring Harbor Laboratory) (17 publications)
Nature (9 publications)
Acta Neuropathologica Communications (8 publications)
Acta Neuropathologica (7 publications)

Among their recent papers are:

Structure-based classification of tauopathies, 2021, Nature
Structures of α-synuclein filaments from multiple system atrophy, 2020, Nature
Novel tau filament fold in corticobasal degeneration, 2020, Nature
Structures of α-synuclein filaments from human brains with Lewy pathology, 2022, Nature
Structure of pathological TDP-43 filaments from ALS with FTLD, 2021, Nature

They have collaborated frequently with co-authors such as Shigeo Murayama, Mari Yoshida, Airi Tarutani, Yuko Saito, and Michel Goedert, with collaboration counts ranging from 25 to 44 publications per co-author.

Hasegawa's academic contributions also include book publications with publishers such as Springer Nature and Cornell University Press eBooks. Notable books include Frontotemporal Dementias published in 2021 and Imperial Gateway published in 2022.

Best Publications

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

M G Spillantini;R A Crowther;R Jakes;M Hasegawa

3895
Citations
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai;Masato Hasegawa;Haruhiko Akiyama;Kenji Ikeda

3532
Citations
|[alpha]|-Synuclein is phosphorylated in synucleinopathy lesions

Hideo Fujiwara;Masato Hasegawa;Naoshi Dohmae;Akiko Kawashima

2527
Citations
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

M. Goedert;R. Jakes;M. G. Spillantini;M. G. Spillantini;M. Hasegawa

1264
Citations
Structure-based classification of tauopathies

Yang Shi;Wenjuan Zhang;Yang Yang;Alexey G. Murzin

882
Citations
Prion-like spreading of pathological α-synuclein in brain

Masami Masuda-Suzukake;Takashi Nonaka;Masato Hosokawa;Takayuki Oikawa

868
Citations
Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease

Fuyuki Kametani;Masato Hasegawa

863
Citations
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

Masato Hasegawa;Tetsuaki Arai;Takashi Nonaka;Fuyuki Kametani

778
Citations
PROLINE-DIRECTED AND NON-PROLINE-DIRECTED PHOSPHORYLATION OF PHF-TAU

Maho Morishima-Kawashima;Masato Hasegawa;Koji Takio;Masami Suzuki

715
Citations
Drug screening for ALS using patient-specific induced pluripotent stem cells.

Naohiro Egawa;Shiho Kitaoka;Kayoko Tsukita;Motoko Naitoh

661
Citations
Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly

Masato Hasegawa;Michael J Smith;Michel Goedert

660
Citations
Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins

Sayuri Taniguchi;Nobuyuki Suzuki;Masami Masuda;Shin-ichi Hisanaga

637
Citations
Structures of α-synuclein filaments from multiple system atrophy

Manuel Schweighauser;Yang Shi;Airi Tarutani;Airi Tarutani;Fuyuki Kametani

560
Citations
High Prevalence of Mutations in the Microtubule-Associated Protein Tau in a Population Study of Frontotemporal Dementia in the Netherlands

Patrizia Rizzu;John C. Van Swieten;Marijke Joosse;Masato Hasegawa

518
Citations
Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains

Takashi Nonaka;Masami Masuda-Suzukake;Tetsuaki Arai;Tetsuaki Arai;Yoko Hasegawa

517
Citations
Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.

Orso Bugiani;Jill R. Murrell;Giorgio Giaccone;Masato Hasegawa

510
Citations
Small Molecule Inhibitors of α-Synuclein Filament Assembly†

Masami Masuda;Nobuyuki Suzuki;Sayuri Taniguchi;Takayuki Oikawa

509
Citations
Phosphorylated α-Synuclein Is Ubiquitinated in α-Synucleinopathy Lesions

Masato Hasegawa;Hideo Fujiwara;Takashi Nonaka;Koichi Wakabayashi

477
Citations
Novel tau filament fold in corticobasal degeneration

Wenjuan Zhang;Airi Tarutani;Kathy L. Newell;Alexey G. Murzin

457
Citations
Seeded Aggregation and Toxicity of α-Synuclein and Tau: CELLULAR MODELS OF NEURODEGENERATIVE DISEASES*

Takashi Nonaka;Sayuri T. Watanabe;Takeshi Iwatsubo;Masato Hasegawa

437
Citations