What is he best known for?
The fields of study he is best known for:
Yasuo Ihara spends much of his time researching Biochemistry, Senile plaques, Molecular biology, Alzheimer's disease and Amyloid.
His studies link Amyloid precursor protein secretase with Biochemistry.
Yasuo Ihara has included themes like Cerebral cortex, Beta, Brefeldin A, Intracellular and Secretory pathway in his Senile plaques study.
His research integrates issues of Microtubule-associated protein, Complementary DNA, Phosphorylation, Neurofibrillary tangle and Antibody in his study of Molecular biology.
His Alzheimer's disease research is multidisciplinary, relying on both Endocrinology, Pathogenesis and Degenerative disease.
His study on Amyloid also encompasses disciplines like
- Amyloid beta, which have a strong connection to Oligopeptide and Tripeptide,
- Amyloid precursor protein together with Presenilin.
His most cited work include:
- Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43) (1477 citations)
- Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease (1153 citations)
- Ubiquitin is a component of paired helical filaments in Alzheimer's disease (743 citations)
What are the main themes of his work throughout his whole career to date?
Yasuo Ihara mainly focuses on Pathology, Biochemistry, Alzheimer's disease, Molecular biology and Cell biology.
His research investigates the connection between Biochemistry and topics such as Presenilin that intersect with problems in Mutant, Amyloid precursor protein and Transmembrane domain.
His Alzheimer's disease research includes themes of Degenerative disease, Endocrinology, Apolipoprotein E and Amyloid.
Yasuo Ihara combines subjects such as P3 peptide, Complementary DNA, Phosphorylation and Antibody, Monoclonal antibody with his study of Molecular biology.
His Cell biology research incorporates themes from Paired helical filaments, Pathogenesis and Tauopathy.
His study in Senile plaques is interdisciplinary in nature, drawing from both Cerebral cortex, Amyloid beta, Beta and Cerebral amyloid angiopathy.
He most often published in these fields:
- Pathology (26.30%)
- Biochemistry (24.07%)
- Alzheimer's disease (22.22%)
What were the highlights of his more recent work (between 2011-2021)?
- Cell biology (16.30%)
- Pathology (26.30%)
- Alzheimer's disease (22.22%)
In recent papers he was focusing on the following fields of study:
Yasuo Ihara focuses on Cell biology, Pathology, Alzheimer's disease, Biochemistry and Disease.
The Cell biology study combines topics in areas such as Pathogenesis and Tauopathy.
His work on Amyloid and Amyloid precursor protein secretase as part of general Pathology study is frequently linked to Mass spectrometry imaging, therefore connecting diverse disciplines of science.
The study incorporates disciplines such as Molecular biology and Parenchyma in addition to Amyloid.
His work carried out in the field of Alzheimer's disease brings together such families of science as Microtubule-associated protein 2 and Microtubule-associated protein.
His Peptide sequence, Cleavage, Amino acid and Adrenergic receptor study in the realm of Biochemistry connects with subjects such as Brain dysfunction.
Between 2011 and 2021, his most popular works were:
- SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians (128 citations)
- The Ubiquitin–Proteasome System and the Autophagic–Lysosomal System in Alzheimer Disease (119 citations)
- γ-Secretase Modulators and Presenilin 1 Mutants Act Differently on Presenilin/γ-Secretase Function to Cleave Aβ42 and Aβ43 (78 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Pathology, Alzheimer's disease, Biochemistry, Amyloid precursor protein secretase and SNP.
Specifically, his work in Pathology is concerned with the study of Amyloid.
His study on Cerebral amyloid angiopathy and Senile plaques is often connected to Mass spectrometry imaging and MALDI imaging as part of broader study in Amyloid.
His Alzheimer's disease study integrates concerns from other disciplines, such as Endocrinology, Control subjects, Cerebrospinal fluid and Cognitive impairment.
His study in Cell biology extends to Biochemistry with its themes.
As part of the same scientific family, Yasuo Ihara usually focuses on Amyloid precursor protein secretase, concentrating on γ secretase and intersecting with Loss function, Protein precursor, Semagacestat, Intracellular and Pharmacology.
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