World's Best Scientists 2026 revealed!
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Medicine
UK
2023

D-Index & Metrics

Neuroscience

D-Index
157
Citations
101671
World Ranking
124
National Ranking
19

Research.com Recognitions

  • 2023 - Research.com Medicine in United Kingdom Leader Award

Overview

John T. O'Brien is affiliated with the University of Cambridge in the United Kingdom. Their research primarily spans the fields of Medicine and Neuroscience, with a significant focus on Neurology, Psychiatry and Mental Health, Physiology, Cognitive Neuroscience, and Radiology, Nuclear Medicine and Imaging.

The scientist's main topics of work include:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Functional Brain Connectivity Studies
  • Parkinson's Disease Mechanisms and Treatments
  • Advanced Neuroimaging Techniques and Applications
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurological Disease Mechanisms and Treatments

Frequent publication venues for their work include:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain Communications
  • Brain
  • Journal of Neurology Neurosurgery & Psychiatry

Their research output is demonstrated by recent papers such as:

  • Research criteria for the diagnosis of prodromal dementia with Lewy bodies, 2020, published in Neurology
  • Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium, 2020, Newcastle University ePrints (Newcastle University)
  • A synergistic core for human brain evolution and cognition, 2022, Nature Neuroscience
  • Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID-19 pandemic, now and in the future, 2020, Alzheimer s & Dementia
  • Drug repositioning and repurposing for Alzheimer disease, 2020, Nature Reviews Neurology

John T. O'Brien frequently collaborates with other researchers including James B. Rowe, John-Paul Taylor, Elijah Mak, Alan Thomas, and Craig Ritchie.

Best Publications

  • Diagnosis and management of dementia with Lewy bodies: Third report of the DLB Consortium

    I. G. McKeith;I. G. McKeith;D. W. Dickson;J. Lowe;M. Emre

  • Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria

    Bruno Dubois;Howard H. Feldman;Claudia Jacova;Steven T. DeKosky

  • Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

    Joanna M. Wardlaw;Eric E. Smith;Geert J Biessels;Charlotte Cordonnier

  • Diagnosis and management of dementia with Lewy bodies Fourth consensus report of the DLB Consortium

    Ian G. McKeith;Bradley F. Boeve;Dennis W. DIckson;Glenda Halliday

  • Revising the definition of Alzheimer's disease: a new lexicon.

    Bruno Dubois;Howard H. Feldman;Howard H. Feldman;Howard H. Feldman;Claudia Jacova;Jeffrey L. Cummings

  • Vascular Cognitive Impairment

    John T O'Brien;Timo Erkinjuntti;Barry Reisberg;Gustavo Roman

  • Donepezil and memantine for moderate-to-severe Alzheimer's disease.

    Robert Howard;Rupert McShane;James Lindesay;Craig Ritchie

  • Diagnostic criteria for vascular cognitive disorders: a VASCOG statement.

    Perminder Sachdev;Raj Kalaria;John O'Brien;Ingmar Skoog

  • Cerebral atrophy in Parkinson’s disease with and without dementia: a comparison with Alzheimer’s disease, dementia with Lewy bodies and controls

    Emma J Burton;Ian G McKeith;David J Burn;E David Williams

  • EFNS guidelines for the diagnosis and management of Alzheimer's disease

    J. Hort;J.T. O'Brien;G. Gainotti;T. Pirttila

  • Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: a phase III, multicentre study

    Ian McKeith;John O'Brien;Zuzana Walker;Klaus Tatsch

  • Research criteria for the diagnosis of prodromal dementia with Lewy bodies

    Ian G. McKeith;Tanis J. Ferman;Alan J. Thomas;Frédéric Blanc

  • Vascular dysfunction-The disregarded partner of Alzheimer's disease

    Melanie D. Sweeney;Axel Montagne;Abhay P. Sagare;Daniel A. Nation

  • White Matter Lesions in an Unselected Cohort of the Elderly: Molecular Pathology Suggests Origin From Chronic Hypoperfusion Injury

    Malee S. Fernando;Julie E. Simpson;Fiona Matthews;Carol Brayne

  • Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa.

    Clive G. Ballard;John T. O'Brien;Katharina Reichelt;Elaine K. Perry

  • Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial

    Sube Banerjee;Jennifer Hellier;Michael Dewey;Renee Romeo

  • Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis

    T Wise;J Radua;J Radua;E Via;N Cardoner

  • Core outcome measures for interventions to prevent or slow the progress of dementia for people living with mild to moderate dementia: Systematic review and consensus recommendations

    Lucy Webster;Derek Groskreutz;Anna Grinbergs-Saull Grinbergs-Saull;Rob Howard

  • Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms

    Diane Otterness;Carol Szumlanski;Lynne Lennard;Bjørg Klemetsdal

  • The spectrum of nonmotor symptoms in early Parkinson disease

    Tien Kheng Khoo;Alison J Yarnall;Gordon W Duncan;Shirley Coleman

  • Prospective validation of consensus criteria for the diagnosis of dementia with Lewy bodies.

    I.G. McKeith;C.G. Ballard;R.H. Perry;P.G. Ince

  • White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer’s disease, vascular dementia, and normal aging

    R. Barber;P. Scheltens;A. Gholkar;C. Ballard

  • Motor subtype and cognitive decline in Parkinson’s disease, Parkinson’s disease with dementia, and dementia with Lewy bodies

    David Burn;Elise Rowan;Louise Allan;Sophie Molloy

Frequent Co-Authors

Michael J. Firbank
Michael J. Firbank Newcastle University
Alan J. Thomas
Alan J. Thomas Newcastle University
James B. Rowe
James B. Rowe University of Cambridge
John-Paul Taylor
John-Paul Taylor Newcastle University
Sean J. Colloby
Sean J. Colloby Newcastle University
Andrew M. Blamire
Andrew M. Blamire Newcastle University
Luca Passamonti
Luca Passamonti University of Cambridge
Robert H. Perry
Robert H. Perry Newcastle University
Franklin I. Aigbirhio
Franklin I. Aigbirhio University of Cambridge
Tim D. Fryer
Tim D. Fryer University of Cambridge

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