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Molecular Biology

D-Index
57
Citations
11624
World Ranking
2147
National Ranking
1066

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Sandra L. Wolin is affiliated with the National Cancer Institute in the United States. Their research focuses extensively on the biochemistry, genetics, and molecular biology fields, with significant contributions to molecular biology, immunology, genetics, cancer research, and radiology, nuclear medicine, and imaging subfields.

The primary topics of Sandra L. Wolin's work include:

  • RNA and protein synthesis mechanisms
  • RNA research and splicing
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases
  • Bacterial genetics and biotechnology
  • CRISPR and genetic engineering

Their recent publications cover a range of topics connected to RNA biology and repair mechanisms. These include:

  • "A guide to naming human non-coding RNA genes," 2020, The EMBO Journal
  • "An RNA Repair Operon Regulated by Damaged tRNAs," 2020, Cell Reports
  • "Transfer RNA halves are found as nicked tRNAs in cells: evidence that nicked tRNAs regulate expression of an RNA repair operon," 2023, RNA
  • "The Bacterial Ro60 Protein and Its Noncoding Y RNA Regulators," 2020, Annual Review of Microbiology
  • "Noncoding Y RNAs regulate the levels, subcellular distribution and protein interactions of their Ro60 autoantigen partner," 2020, Nucleic Acids Research

Sandra collaborates frequently with several coauthors, including Xinguo Chen, Soyeong Sim, Kevin J. Hughes, Yuanyuan Leng, and J. Alberto Ortega. These repeated collaborations indicate a sustained engagement with partners working in related research areas.

The scientist's work has been published several times in key venues such as RNA, bioRxiv (Cold Spring Harbor Laboratory), Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, The EMBO Journal, and Cell Reports.

In recognition of their contributions, Sandra L. Wolin was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2013.

Best Publications

  • Are snRNPs involved in splicing

    Michael R. Lerner;John A. Boyle;Stephen M. Mount;Sandra L. Wolin

  • THE LA PROTEIN

    Sandra L. Wolin;Tommy Cedervall

  • Ribosome pausing and stacking during translation of a eukaryotic mRNA.

    S L Wolin;P Walter

  • Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells.

    J P Hendrick;S L Wolin;J Rinke;M R Lerner

  • The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs

    Sandra L. Wolin;Joan A. Steitz

  • Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle.

    Anita G. Seto;Arthur J. Zaug;Suzanne G. Sobel;Sandra L. Wolin

  • The yeast La protein is required for the 3' endonucleolytic cleavage that matures tRNA precursors.

    Christopher J Yoo;Sandra L Wolin

  • RNA under attack: cellular handling of RNA damage.

    Elisabeth J. Wurtmann;Sandra L. Wolin

  • A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcripts.

    Barbara K. Pannone;Dahai Xue;Sandra L. Wolin

  • A possible role for the 60-kD Ro autoantigen in a discard pathway for defective 5S rRNA precursors.

    C A O'Brien;S L Wolin

  • A perinucleolar compartment contains several RNA polymerase III transcripts as well as the polypyrimidine tract-binding protein, hnRNP I.

    A G Matera;M R Frey;K Margelot;S L Wolin

  • Genes for two small cytoplasmic Ro RNAs are adjacent and appear to be single-copy in the human genome

    Sandra L. Wolin;Joan A. Steitz

  • Structural Insights into RNA Quality Control: The Ro Autoantigen Binds Misfolded RNAs via Its Central Cavity

    Adam J. Stein;Gabriele Fuchs;Chunmei Fu;Sandra L. Wolin

  • The trials and travels of tRNA

    S L Wolin;A G Matera

  • Signal recognition particle mediates a transient elongation arrest of preprolactin in reticulocyte lysate.

    S L Wolin;P Walter

  • La proteins from Drosophila melanogaster and Saccharomyces cerevisiae: a yeast homolog of the La autoantigen is dispensable for growth.

    C J Yoo;S L Wolin

  • A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen

    Dahai Xue;Hong Shi;James D. Smith;Xinguo Chen

  • The RtcB RNA ligase is an essential component of the metazoan unfolded protein response

    Sara Guckian Kosmaczewski;Tyson James Edwards;Sung Min Han;Matthew J Eckwahl

  • Nuclear lamin LI of Xenopus laevis: cDNA cloning, amino acid sequence and binding specificity of a member of the lamin B subfamily.

    G. Krohne;S. L. Wolin;F. D. McKeon;Werner W. Franke

  • Antibodies from patients with connective tissue diseases bind specific subsets of cellular RNA-protein particles.

    John A. Hardin;Daniel R. Rahn;Calvin Shen;Michael R. Lerner

Frequent Co-Authors

Joan A. Steitz
Joan A. Steitz Yale University
Andrew L. Goodman
Andrew L. Goodman Yale University
Paul D. Bieniasz
Paul D. Bieniasz Rockefeller University
Peter Walter
Peter Walter University of California, San Francisco
Elspeth A. Bruford
Elspeth A. Bruford University of Cambridge
Yong Xiong
Yong Xiong Yale University
Marc W. Kirschner
Marc W. Kirschner Harvard University
Hong-Wei Wang
Hong-Wei Wang Tsinghua University
John A. Hardin
John A. Hardin Albert Einstein College of Medicine
Richard A. Flavell
Richard A. Flavell Yale University

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